PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Rsa1.0_00308.1_g00005.1
Organism
Raphanus sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family E2F/DP
Protein Properties Length: 481aa    MW: 52420.2 Da    PI: 4.8043
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Rsa1.0_00308.1_g00005.1genomeRGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP82.24.4e-26161226171
                  E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                              r+++sL+llt+kf++l++++++g+++ln++a++L   +v  ++RRiYDi+NVLe+++liek  kn+i wkg
  Rsa1.0_00308.1_g00005.1 161 RYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETL---EV--QKRRIYDITNVLEGIDLIEKPFKNRILWKG 226
                              6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.107.3E-28157228IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.63E-16161224IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.2E-32161226IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023199.1E-23163226IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146602.05E-47239343No hitNo description
SuperFamilySSF1440746.8E-32240343No hitNo description
PfamPF164213.0E-32243341IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 481 aa     Download sequence    Send to blast
MSGGARTSPG PSQPPPPPQH PPSSSVPVVP PIRRHLAFAS TKPPFNPSDY HRFAPPHLTN  60
NDRSLVNLCG AVDREDDVVV HRSPSRKRKT TTDVVAASSN SNGFTSSGFS TISNSPCKTP  120
VSAKGGRVNT KSKAKGNQSV PQTPISNASS PPTLTPSGSC RYDSSLGLLT KKFVNLIKQA  180
KDGMLDLNKA AETLEVQKRR IYDITNVLEG IDLIEKPFKN RILWKGVDTS GPGDVDADIS  240
VVQAEIENLS LEEQALDNQI RETEERLRDL SENEKNQKWL FVTEEDIKTL PGFQNQTLIA  300
VKAPHGTTLE VPDPDEAVDS PQRRYRIILR STMGPIDVYL VSEFEKKFEE TNGTAAPAAC  360
LPIASCSGSS ENHEIEALTV DNKGTDNEHH QVSQDHAHAQ PGDASDLNYL QEQVGGMLKI  420
TPSDVENDDT DYWLLSNADI SMTDIWKTDS GIDWDYEIAD VSTPPPVMGE IAPTGIDSTP  480
R
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A3e-23156227274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
18489SRKRKT
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00293DAPTransfer from AT2G36010Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapRsa1.0_00308.1_g00005.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankJN9429840.0JN942984.1 Brassica juncea E2F transcription factor (E2Fa) mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018477559.10.0PREDICTED: transcription factor E2FA-like
RefseqXP_018477589.10.0PREDICTED: transcription factor E2FA-like
SwissprotQ9FNY00.0E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A3N6U3X70.0A0A3N6U3X7_BRACR; Uncharacterized protein
STRINGBra017268.1-P0.0(Brassica rapa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM80828121
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.10.0E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]