PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Rsa1.0_00119.1_g00017.1

Organism

Raphanus sativus

Taxonomic ID

3726

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

MIKC_MADS

Protein Properties

Length: 193aa MW: 21788.4 Da PI: 8.1896

Description

MIKC_MADS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Rsa1.0_00119.1_g00017.1	genome	RGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	SRF-TF	100.4	6.7e-32	22	72	1	51
S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS SRF-TF 1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51 krien++nrqvtf+kRrng+lKKA+ELSvLCdaeva+i+fss+g+lyeys+ Rsa1.0_00119.1_g00017.1 22 KRIENTTNRQVTFCKRRNGLLKKAYELSVLCDAEVALIVFSSRGRLYEYSN 72 79***********************************************95 PP
2	K-box	21.4	1e-08	100	132	68	100
K-box 68 kKnellleqieelqkkekelqeenkaLrkklee 100 +nell+++i+++qk+e +l+++n+ Lr+k++e Rsa1.0_00119.1_g00017.1 100 AQNELLFAEIDYTQKREADLHSDNELLRAKIAE 132 589***************************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00432	3.5E-41	14	73	IPR002100	Transcription factor, MADS-box
PROSITE profile	PS50066	33.165	14	74	IPR002100	Transcription factor, MADS-box
CDD	cd00265	5.87E-48	15	88	No hit	No description
SuperFamily	SSF55455	1.44E-33	15	89	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	3.7E-33	16	36	IPR002100	Transcription factor, MADS-box
PROSITE pattern	PS00350	0	16	70	IPR002100	Transcription factor, MADS-box
Pfam	PF00319	6.1E-27	23	70	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	3.7E-33	36	51	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	3.7E-33	51	72	IPR002100	Transcription factor, MADS-box

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 193 aa Download sequence Send to blast
MELGGDFSPQ RKSGGRGKIE IKRIENTTNR QVTFCKRRNG LLKKAYELSV LCDAEVALIV 60 FSSRGRLYEY SNNSVKGTIE RYKKAISDNT NTGTVAEINA QNELLFAEID YTQKREADLH 120 SDNELLRAKI AENEGNNPSM NLMPGGYEQI MQPLQTQPQP FDSRNYFQVA ALQPNNHHYS 180 SAGRQDQTAL QLV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1egw_A	2e-20	15	82	1	68	MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE A
1egw_B	2e-20	15	82	1	68	MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE A
1egw_C	2e-20	15	82	1	68	MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE A
1egw_D	2e-20	15	82	1	68	MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE A
3kov_A	2e-20	15	82	1	68	Myocyte-specific enhancer factor 2A
3kov_B	2e-20	15	82	1	68	Myocyte-specific enhancer factor 2A
3kov_I	2e-20	15	82	1	68	Myocyte-specific enhancer factor 2A
3kov_J	2e-20	15	82	1	68	Myocyte-specific enhancer factor 2A
3mu6_A	1e-20	15	82	1	68	Myocyte-specific enhancer factor 2A
3mu6_B	1e-20	15	82	1	68	Myocyte-specific enhancer factor 2A
3mu6_C	1e-20	15	82	1	68	Myocyte-specific enhancer factor 2A
3mu6_D	1e-20	15	82	1	68	Myocyte-specific enhancer factor 2A
3p57_A	2e-20	15	82	1	68	Myocyte-specific enhancer factor 2A
3p57_B	2e-20	15	82	1	68	Myocyte-specific enhancer factor 2A
3p57_C	2e-20	15	82	1	68	Myocyte-specific enhancer factor 2A
3p57_D	2e-20	15	82	1	68	Myocyte-specific enhancer factor 2A
3p57_I	2e-20	15	82	1	68	Myocyte-specific enhancer factor 2A
3p57_J	2e-20	15	82	1	68	Myocyte-specific enhancer factor 2A
6c9l_E	2e-20	15	82	2	69	Myocyte-specific enhancer factor 2B
6c9l_F	2e-20	15	82	2	69	Myocyte-specific enhancer factor 2B
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor involved in the control of organ identity during the early development of flowers. Is required for normal development of stamens and carpels in the wild-type flower. Plays a role in maintaining the determinacy of the floral meristem. Acts as C class cadastral protein by repressing the A class floral homeotic genes like APETALA1. Forms a heterodimer via the K-box domain with either SEPALATTA1/AGL2, SEPALATTA2/AGL4, SEPALLATA3/AGL9 or AGL6 that could be involved in genes regulation during floral meristem development. Controls AHL21/GIK, a multifunctional chromatin modifier in reproductive organ patterning and differentiation (PubMed:19956801). Induces microsporogenesis through the activation of SPL/NZZ (PubMed:15254538). {ECO:0000269\|PubMed:15254538, ECO:0000269\|PubMed:19956801}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Rsa1.0_00119.1_g00017.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by the A class floral homeotic protein APETALA2 and by other repressors like LEUNIG, SEUSS, SAP or CURLY LEAF. Positively regulated by both LEAFY and APETALA1. Repressed by silencing mediated by polycomb group (PcG) protein complex containing EMF1 and EMF2. Up-regulated by HUA2. {ECO:0000269\|PubMed:10198637, ECO:0000269\|PubMed:11058164, ECO:0000269\|PubMed:1675158, ECO:0000269\|PubMed:17794879, ECO:0000269\|PubMed:18281509, ECO:0000269\|PubMed:19783648, ECO:0000269\|PubMed:9783581}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY277692	1e-125	AY277692.1 Eruca sativa AGAMOUS-like protein EsAG3 mRNA, partial cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018480894.1	1e-128	PREDICTED: floral homeotic protein AGAMOUS-like isoform X2
Refseq	XP_018480895.1	1e-128	PREDICTED: floral homeotic protein AGAMOUS-like isoform X3
Swissprot	P17839	1e-110	AG_ARATH; Floral homeotic protein AGAMOUS
TrEMBL	A0A397L4K8	1e-115	A0A397L4K8_BRACM; Uncharacterized protein
TrEMBL	M4D7V4	1e-115	M4D7V4_BRARP; Uncharacterized protein
STRING	Bra012564.1-P	1e-115	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6181	22	37

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G18960.1	1e-113	MIKC_MADS family protein

Publications ? help Back to Top
Huang Z, et al. APETALA2 antagonizes the transcriptional activity of AGAMOUS in regulating floral stem cells in Arabidopsis thaliana. New Phytol., 2017. 215(3): p. 1197-1209 [PMID:27604611] Rong XF, et al. Type-B ARRs Control Carpel Regeneration Through Mediating AGAMOUS Expression in Arabidopsis. Plant Cell Physiol., 2018. 59(4): p. 756-764 [PMID:29186581] Uemura A, et al. Regulation of floral meristem activity through the interaction of AGAMOUS, SUPERMAN, and CLAVATA3 in Arabidopsis. Plant Reprod, 2018. 31(1): p. 89-105 [PMID:29218596]