PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Phvul.003G196600.1
Common NamePHAVU_003G196600g
Organism
Phaseolus vulgaris
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Phaseolus
Family E2F/DP
Protein Properties Length: 382aa    MW: 43121.2 Da    PI: 9.1633
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Phvul.003G196600.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP75.55.3e-241681171
             E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                        rk+ksL+ll+++fl+l+++     + l+++a++L    v  +rRRiYDi+NVLe+++++++k+kn+++wkg
  Phvul.003G196600.1 16 RKQKSLGLLCTNFLSLYNRDAVHLIGLDDAATRL---GV--ERRRIYDIVNVLESIGVLSRKAKNQYTWKG 81
                        79*****************999************...**..****************************98 PP
2E2F_TDP76.92e-24152232171
             E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                         r+eksL lltq+f+kl+ +s+ + ++l+e+ak L+ +      +++k+RR+YDi+NVL+++nliek     ++k+++rw g
  Phvul.003G196600.1 152 RREKSLALLTQNFVKLFVCSNVELISLDEAAKLLLGDahntsIMRTKVRRLYDIANVLSSMNLIEKthtsdTRKPAFRWLG 232
                         689**************************************999**************************99*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.105.5E-261282IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.18E-161579IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.5E-281681IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023198.2E-211781IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.102.6E-23149234IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.7E-32152232IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467856.49E-14154233IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.4E-19154232IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 382 aa     Download sequence    Send to blast
MASSDPISSK HYTYNRKQKS LGLLCTNFLS LYNRDAVHLI GLDDAATRLG VERRRIYDIV  60
NVLESIGVLS RKAKNQYTWK GFAAIPLTLR ELKEDGQREN SNSLRGSTND DMDKVSDDED  120
DEETQSNAAT GSQNDKLNPK STQPRSLKNE NRREKSLALL TQNFVKLFVC SNVELISLDE  180
AAKLLLGDAH NTSIMRTKVR RLYDIANVLS SMNLIEKTHT SDTRKPAFRW LGPEGKTWNE  240
SLHKSNQNDS RKRAFGSDIT NISFERSKVE LFTNGDLNSN PKKLKIENDI EPGQADENNL  300
KQDTKQTSKS YQFGPFAPAC VPRVGASGKH NGKQVHDWDG LVNAHSPQYQ NEALKDLFSH  360
YMEAWKSWYS EIAAKRPLQI L*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A2e-40152243228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapPhvul.003G196600.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007155383.10.0hypothetical protein PHAVU_003G196600g
SwissprotQ8LSZ41e-127E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLV7CB150.0V7CB15_PHAVU; Uncharacterized protein
STRINGXP_007155383.10.0(Phaseolus vulgaris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36683366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-129DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]