PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pavir.1NG446300.1.p
Organism
Panicum virgatum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Panicinae; Panicum
Family E2F/DP
Protein Properties Length: 418aa    MW: 45387.1 Da    PI: 5.0845
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pavir.1NG446300.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP83.32e-26150215171
              E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                          r+++sL+llt+kf++ll+++++gi++ln +a++L   +v  ++RRiYDi+NVLe+++liek+ kn+irwkg
  Pavir.1NG446300.1.p 150 RYDSSLGLLTKKFINLLKQAPDGILDLNIAAETL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIRWKG 215
                          6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.7E-28147217IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.3E-35150215IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.16E-17150213IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023197.7E-24152215IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146607.73E-52225331No hitNo description
SuperFamilySSF1440743.4E-35227331No hitNo description
PfamPF164218.9E-35230329IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 418 aa     Download sequence    Send to blast
MSGVGSGRPP AAQKILQSLR PPIAFASPSR PPFAAPDDYH RFPTPAAAAA PAATSGGVGA  60
AGASDTIEEG LVIRTPLKRK ATSEDNDAAE SSDCIITSTG FPGSSMLTPV SGKTVKTSKS  120
KAKNNKAGPQ TPTSNVGSPL NPETPAGTCR YDSSLGLLTK KFINLLKQAP DGILDLNIAA  180
ETLEVQKRRI YDITNVLEGI GLIEKTLKNR IRWKGLDDSG VDLDNGISAL QAEVENLSLQ  240
EQALDEHIRD MREKLRGLTE DENNQRWLYV TEDDIKRLPC FQNETLIAIK APHGTTLEVP  300
DPDEVGDYLQ RRYRIVLRST MGPIDVYLVS QFDEKFEDLG GVATPTRHTN MPRRYPIEDS  360
NTTNGGQCST AMDVEQNVQQ SQRTPQDPSA LHDFGGMTRI IPSDVDVSQI FLKFILF*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A9e-25145216174PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}.
UniprotTISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPavir.1NG446300.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_025798973.10.0transcription factor E2FA-like isoform X2
SwissprotQ9FNY01e-125E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A2S3GPL90.0A0A2S3GPL9_9POAL; Uncharacterized protein
STRINGPavir.J38646.1.p0.0(Panicum virgatum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP62537148
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-114E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]