PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pta003283
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Pinus; Pinus
Family Dof
Protein Properties Length: 288aa    MW: 31571.7 Da    PI: 7.4422
Description Dof family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Pta#S25643854PU_unrefUnigeneView CDS
PUT-157a-Pinus_taeda-38028PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-Dof122.41.5e-382786362
     zf-Dof  3 ekalkcprCdstntkfCyynnyslsqPryfCkaCrryWtkGGalrnvPvGggrrknkkss 62
               +++lkcprCdstntkfCyynnysl+qPr+fCk+CrryWtkGG+lr vPvGgg+rkn k++
  Pta003283 27 QEILKCPRCDSTNTKFCYYNNYSLTQPRHFCKTCRRYWTKGGSLRSVPVGGGCRKNSKRN 86
               6889****************************************************9875 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
ProDomPD0074785.0E-241879IPR003851Zinc finger, Dof-type
PfamPF027019.2E-332884IPR003851Zinc finger, Dof-type
PROSITE profilePS5088429.0683084IPR003851Zinc finger, Dof-type
PROSITE patternPS0136103268IPR003851Zinc finger, Dof-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 288 aa     Download sequence    Send to blast
MEGTADMMDS YPPRQLLDRR MKPQADQEIL KCPRCDSTNT KFCYYNNYSL TQPRHFCKTC  60
RRYWTKGGSL RSVPVGGGCR KNSKRNNSNN NNGKRSSGEA CSSATGSDQL SPSLAGVSND  120
CKYYNGDGEE LIGINYVNSL RQVDHEAAFA GCSINSGVYG IQANDHQSSQ SFQPYHLPTA  180
LQSLQGSLIL GSDQAPNGFN QAANRGDLGL VQQQAAGAVP YDREAYHPYI NMSLDQSDGH  240
SRAPQQHKGN NIIEHPPQGI VYEGGYWNSG VWPDLSAYGL SNINPNSM
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Pta.66750.0needle| root| xylem
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: In embryos, present in cells relevant for root initiation and later in vascular tissues. At the globular stage, accumulates in cells adjacent to the hypophysis (extra-embryonic cell specified to become the founder cell of the primary root meristem) (PubMed:20220754). Expressed at preprocambial stages first in wide domains, and later confined to sites of vein development. In young seedlings, first observed in the central region of leaves primordia, and later strongly expressed at sites of midvein, first and second loops, and higher-order veins (PubMed:20563990). {ECO:0000269|PubMed:20220754, ECO:0000269|PubMed:20563990}.
UniprotTISSUE SPECIFICITY: The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) form a short-range concentration gradient that peaks at protophloem sieve elements (PSE) (PubMed:30626969). Accumulates in the stele (PubMed:20563990). {ECO:0000269|PubMed:20563990, ECO:0000269|PubMed:30626969}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) activate gene expression that promotes radial growth of protophloem sieve elements (PubMed:30626969). {ECO:0000250|UniProtKB:Q9M2U1, ECO:0000269|PubMed:30626969}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By cytokinin in procambium (PubMed:30626969). Induced by the transcription factor MONOPTEROS (MP) in cells relevant for root initiation, and later in vascular tissues and hypophysis (PubMed:20220754). {ECO:0000269|PubMed:20220754, ECO:0000269|PubMed:30626969}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
SwissprotQ84TE97e-33DOF53_ARATH; Dof zinc finger protein DOF5.3
TrEMBLT2B8B80.0T2B8B8_PINPS; Dof9
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60200.17e-32TARGET OF MONOPTEROS 6
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Miyashima S, et al.
    Mobile PEAR transcription factors integrate positional cues to prime cambial growth.
    Nature, 2019. 565(7740): p. 490-494
    [PMID:30626969]