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Plant Transcription
Factor Database
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Transcription Factor Information
Basic
Information? help
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TF ID |
Psi011108 |
Organism |
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Taxonomic ID |
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Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Picea
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Family |
E2F/DP |
Protein Properties |
Length: 192aa MW: 20899.4 Da PI: 9.9915 |
Description |
E2F/DP family protein |
Gene Model |
Gene Model ID |
Type |
Source |
Coding Sequence |
gnl|UG|Psi#S55421784 | PU_ref | Unigene | View CDS |
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Signature Domain? help Back to Top |
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No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
1 | E2F_TDP | 30.1 | 7.8e-10 | 150 | 189 | 1 | 43 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkr 43
r+++sL+llt+kf++l++++++g+++ln++a++L dv++k+
Psi011108 150 RYDSSLGLLTKKFISLIKQADDGVLDLNKAADTL---DVQKKK 189
6899******************************...775554 PP
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Gene Ontology ? help Back to Top |
GO Term |
GO Category |
GO Description |
GO:0006355 | Biological Process | regulation of transcription, DNA-templated |
GO:0005667 | Cellular Component | transcription factor complex |
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
Protein Sequence Length: 192 aa
Download sequence Send
to blast |
MSGGRAGNRF QQPAGPLIQP LKRHSAFASN KPAFAASEDY HHFVVTDKAS ASGGNDDDKD 60 NGEMLLLTRF PGKRRAETEE DHEIESNEWP TSQGYVEAVN SPILTPVSGT SGRRYNRSKL 120 AKSMRTGPQT PVSNIGSPSS NVHTPVSTCR YDSSLGLLTK KFISLIKQAD DGVLDLNKAA 180 DTLDVQKKKK KK
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Expression --
Description ? help
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Source |
Description |
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}. |
Uniprot | TISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}. |
Functional Description ? help
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Source |
Description |
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |