PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Prupe.4G102000.1.p
Common NamePRUPE_ppa012421mg
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Amygdaleae; Prunus
Family LSD
Protein Properties Length: 171aa    MW: 17696.6 Da    PI: 8.5541
Description LSD family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Prupe.4G102000.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-LSD140.54.4e-13731125
             zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                        C+gCr +L YPrGA++V+CalC+ +
  Prupe.4G102000.1.p  7 CSGCRSILLYPRGATNVCCALCNII 31
                        **********************976 PP

2zf-LSD143.64.9e-144670125
             zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                        CggCrtlL+ +rGA+sVRC++C+tV
  Prupe.4G102000.1.p 46 CGGCRTLLMHTRGATSVRCSCCHTV 70
                        ************************9 PP

3zf-LSD147.43.1e-1584108125
             zf-LSD1   1 CggCrtlLsYPrGApsVRCalCdtV 25 
                         Cg+Crt+L+YP+GApsV+Ca+C+ V
  Prupe.4G102000.1.p  84 CGNCRTTLMYPYGAPSVKCAVCHYV 108
                         **********************987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
TIGRFAMsTIGR010531.0E-11432IPR005735Zinc finger, LSD1-type
PfamPF069435.3E-11730IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010537.0E-164372IPR005735Zinc finger, LSD1-type
PfamPF069435.2E-124670IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010537.3E-1381111IPR005735Zinc finger, LSD1-type
PfamPF069433.0E-1484108IPR005735Zinc finger, LSD1-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000303Biological Processresponse to superoxide
GO:0001666Biological Processresponse to hypoxia
GO:0002240Biological Processresponse to molecule of oomycetes origin
GO:0009626Biological Processplant-type hypersensitive response
GO:0009862Biological Processsystemic acquired resistance, salicylic acid mediated signaling pathway
GO:0010104Biological Processregulation of ethylene-activated signaling pathway
GO:0010310Biological Processregulation of hydrogen peroxide metabolic process
GO:0010602Biological Processregulation of 1-aminocyclopropane-1-carboxylate metabolic process
GO:0010618Biological Processaerenchyma formation
GO:0043069Biological Processnegative regulation of programmed cell death
Sequence ? help Back to Top
Protein Sequence    Length: 171 aa     Download sequence    Send to blast
MQSQLVCSGC RSILLYPRGA TNVCCALCNI ITPVPPPGTE MAQLICGGCR TLLMHTRGAT  60
SVRCSCCHTV NLAPASSQVA HVNCGNCRTT LMYPYGAPSV KCAVCHYVTN VGMTNMRVPI  120
PVHRPNGTAN SGTAPSTSAS QTVVVENPMS VDESGKLVSN VVVGVTTGKK *
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in cotyledons, roots, rosette leaves, stems, inflorescences and flowers. {ECO:0000269|PubMed:20456049}.
Functional Description ? help Back to Top
Source Description
UniProtNegative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269|PubMed:10550898, ECO:0000269|PubMed:11595797, ECO:0000269|PubMed:11844114, ECO:0000269|PubMed:12732715, ECO:0000269|PubMed:15347794, ECO:0000269|PubMed:16957775, ECO:0000269|PubMed:18055613, ECO:0000269|PubMed:18790826, ECO:0000269|PubMed:20456049, ECO:0000269|PubMed:21097903}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPrupe.4G102000.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By methyl viologen. {ECO:0000269|PubMed:20456049}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007212162.11e-119protein LSD1 isoform X2
RefseqXP_020417737.11e-119protein LSD1 isoform X2
SwissprotP940772e-74LSD1_ARATH; Protein LSD1
TrEMBLM5WHS31e-117M5WHS3_PRUPE; Uncharacterized protein
STRINGEMJ133621e-118(Prunus persica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF40273361
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G20380.78e-77LSD family protein
Publications ? help Back to Top
  1. Spedaletti V, et al.
    Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana.
    Biochemistry, 2008. 47(17): p. 4936-47
    [PMID:18393445]
  2. Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S
    PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties.
    Plant Cell Rep., 2016. 35(3): p. 527-39
    [PMID:26754794]
  3. Czarnocka W, et al.
    The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator.
    Plant Cell Environ., 2017. 40(11): p. 2644-2662
    [PMID:28555890]
  4. Bernacki MJ, et al.
    LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana.
    Physiol Plant, 2019. 165(2): p. 369-382
    [PMID:30461017]