PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Prupe.3G032300.3.p

Common Name

ERF2.a, PRUPE_ppa006366mg

Organism

Prunus persica

Taxonomic ID

3760

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Amygdaleae; Prunus

Family

ERF

Protein Properties

Length: 383aa MW: 42495.9 Da PI: 4.5636

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Prupe.3G032300.3.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	59.4	8.3e-19	112	161	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +y+G+r+++ +g+W+AeIrdp++ r++lg+f taeeAa+a++ +++++g Prupe.3G032300.3.p 112 QYRGIRQRP-WGKWAAEIRDPRK---GVRVWLGTFNTAEEAARAYDSEARRIRG 161 69*****.******954...4**********************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00380	8.0E-38	112	175	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	5.36E-22	112	171	IPR016177	DNA-binding domain
PROSITE profile	PS51032	23.947	112	169	IPR001471	AP2/ERF domain
CDD	cd00018	1.39E-32	112	170	No hit	No description
Gene3D	G3DSA:3.30.730.10	1.9E-32	112	171	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.1E-11	113	124	IPR001471	AP2/ERF domain
Pfam	PF00847	1.5E-11	113	161	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.1E-11	135	151	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0070483	Biological Process	detection of hypoxia
GO:0005634	Cellular Component	nucleus
GO:0005886	Cellular Component	plasma membrane
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 383 aa Download sequence Send to blast
MCGGAIISDF IAPTRSRLTA DYLWPDLKKP SSDKRFSKPL RPEIIDLDHD FEADFQEFKD 60 ESDVDEDDEM VEAKPSAFSA GKPSSARGST TVKLVEFNGQ AEKSAKRKRK NQYRGIRQRP 120 WGKWAAEIRD PRKGVRVWLG TFNTAEEAAR AYDSEARRIR GKKAKVNFPD ETPRSSAKRS 180 VKANPQKMLP KTNTNAVQPN LNQNINFVND PNQDYYNAMG FLDEKPATNN FGFMSTFPAN 240 EDVALKSSTP SDAVPLYFSS DQGSNSFDCS DFGWGEQGSK TPEISSVLSC VMEESDDSLF 300 LEDASPTKKL KSNPEDLVPV QDNAGKTLTD ELSAFEMKYF QTPYLDGSWD ASVDAFLSTD 360 ATQDGGNSVD FWSFDDLIGG GF*

Sequence ? help Back to Top

Protein Sequence Length: 383 aa Download sequence Send to blast

MCGGAIISDF IAPTRSRLTA DYLWPDLKKP SSDKRFSKPL RPEIIDLDHD FEADFQEFKD  60
ESDVDEDDEM VEAKPSAFSA GKPSSARGST TVKLVEFNGQ AEKSAKRKRK NQYRGIRQRP  120
WGKWAAEIRD PRKGVRVWLG TFNTAEEAAR AYDSEARRIR GKKAKVNFPD ETPRSSAKRS  180
VKANPQKMLP KTNTNAVQPN LNQNINFVND PNQDYYNAMG FLDEKPATNN FGFMSTFPAN  240
EDVALKSSTP SDAVPLYFSS DQGSNSFDCS DFGWGEQGSK TPEISSVLSC VMEESDDSLF  300
LEDASPTKKL KSNPEDLVPV QDNAGKTLTD ELSAFEMKYF QTPYLDGSWD ASVDAFLSTD  360
ATQDGGNSVD FWSFDDLIGG GF*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	3e-21	112	169	2	60	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
5wx9_A	6e-21	111	171	13	74	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Ppe.224	0.0	fruit\| leaf

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Highly expressed in seedlings, leaves, flowers, siliques and germinating seeds. {ECO:0000269\|PubMed:22020282}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the activation of hypoxic gene expression and in ethylene response. Partially redundant with RAP2-2. Acts as a downstream regulator in the ethylene signaling pathway. {ECO:0000269\|PubMed:22020282, ECO:0000269\|PubMed:22530619}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00204	DAP	Transfer from AT1G53910	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Prupe.3G032300.3.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by hypoxia but not by ethylene. {ECO:0000269\|PubMed:22020282}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HQ825096	0.0	HQ825096.1 Prunus persica cultivar Venture ethylene responsive factor (ERF2.a) mRNA, partial cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_007215452.1	0.0	ethylene-responsive transcription factor RAP2-12
Swissprot	Q9SSA8	2e-83	RA212_ARATH; Ethylene-responsive transcription factor RAP2-12
TrEMBL	H2BDK5	0.0	H2BDK5_PRUPE; Ethylene responsive factor (Fragment)
STRING	EMJ16652	0.0	(Prunus persica)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G53910.3	2e-83	related to AP2 12

Link Out ? help Back to Top
Phytozome	Prupe.3G032300.3.p
Entrez Gene	18783672

Publications ? help Back to Top
Sherif S,El-Sharkawy I,Paliyath G,Jayasankar S Differential expression of peach ERF transcriptional activators in response to signaling molecules and inoculation with Xanthomonas campestris pv. pruni. J. Plant Physiol., 2012. 169(7): p. 731-9 [PMID:22410465] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kosmacz M, et al. The stability and nuclear localization of the transcription factor RAP2.12 are dynamically regulated by oxygen concentration. Plant Cell Environ., 2015. 38(6): p. 1094-103 [PMID:25438831] Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana. Plant Sci., 2015. 236: p. 37-43 [PMID:26025519] Gasch P, et al. Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis. Plant Cell, 2016. 28(1): p. 160-80 [PMID:26668304] Gonzali S, et al. Universal stress protein HRU1 mediates ROS homeostasis under anoxia. Nat Plants, 2015. 1: p. 15151 [PMID:27251529] Paul MV, et al. Oxygen Sensing via the Ethylene Response Transcription Factor RAP2.12 Affects Plant Metabolism and Performance under Both Normoxia and Hypoxia. Plant Physiol., 2016. 172(1): p. 141-53 [PMID:27372243] Shahzad Z, et al. A Potassium-Dependent Oxygen Sensing Pathway Regulates Plant Root Hydraulics. Cell, 2016. 167(1): p. 87-98.e14 [PMID:27641502] Yao Y, et al. ETHYLENE RESPONSE FACTOR 74 (ERF74) plays an essential role in controlling a respiratory burst oxidase homolog D (RbohD)-dependent mechanism in response to different stresses in Arabidopsis. New Phytol., 2017. 213(4): p. 1667-1681 [PMID:28164334] Giuntoli B,Licausi F,van Veen H,Perata P Functional Balancing of the Hypoxia Regulators RAP2.12 and HRA1 Takes Place in vivo in Arabidopsis thaliana Plants. Front Plant Sci, 2017. 8: p. 591 [PMID:28487707] Yao Y,Chen X,Wu AM ERF-VII members exhibit synergistic and separate roles in Arabidopsis. Plant Signal Behav, 2017. 12(6): p. e1329073 [PMID:28537474] Eysholdt-Derzsó E,Sauter M Root Bending Is Antagonistically Affected by Hypoxia and ERF-Mediated Transcription via Auxin Signaling. Plant Physiol., 2017. 175(1): p. 412-423 [PMID:28698356] Giuntoli B, et al. Age-dependent regulation of ERF-VII transcription factor activity in Arabidopsis thaliana. Plant Cell Environ., 2017. 40(10): p. 2333-2346 [PMID:28741696]