PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Prupe.1G249600.1.p
Common NameKNOPE2
Organism
Prunus persica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Amygdaleae; Prunus
Family TALE
Protein Properties Length: 352aa    MW: 40035.6 Da    PI: 4.8571
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Prupe.1G249600.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox28.23.2e-092943282155
                         HSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
            Homeobox  21 knrypsaeereeLAkklgLterqVkvWFqNrRake 55 
                         k +yp+++++  LA+++gL++rq+ +WF N+R ++
  Prupe.1G249600.1.p 294 KWPYPTEADKIALAESTGLDQRQINNWFINQRKRH 328
                         569*****************************885 PP
2ELK26.91.1e-09248269122
                 ELK   1 ELKhqLlrKYsgyLgsLkqEFs 22 
                         +LK++L+r +++++g+Lk EFs
  Prupe.1G249600.1.p 248 DLKDRLMRRFGSHIGTLKLEFS 269
                         69*******************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM012551.3E-2094138IPR005540KNOX1
PfamPF037905.7E-2195137IPR005540KNOX1
SMARTSM012561.3E-26156207IPR005541KNOX2
PfamPF037911.8E-24161206IPR005541KNOX2
PROSITE profilePS512139.411248268IPR005539ELK domain
PfamPF037893.5E-7248269IPR005539ELK domain
SMARTSM011881.2E-4248269IPR005539ELK domain
PROSITE profilePS5007112.746268331IPR001356Homeobox domain
SuperFamilySSF466891.03E-19269343IPR009057Homeodomain-like
SMARTSM003893.2E-13270335IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.601.2E-27273332IPR009057Homeodomain-like
CDDcd000864.03E-12280332No hitNo description
PfamPF059203.5E-17288327IPR008422Homeobox KN domain
PROSITE patternPS000270306329IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010073Biological Processmeristem maintenance
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 352 aa     Download sequence    Send to blast
MEEMYGLQST AECGDKGFQS TAEYEDRALM TPENLILPLD YQSLLVSSGA FRGEHHHHRV  60
PMFGSDDVVL YSAMSEAASP TITPEFQREE DVFGAIKAKI ASHPTYPRLI HAYIECQKVG  120
APPEIASFLD EIRRESDFYN YKQQQRGSCN SNSSMSSTYL GADPELDEFM ETYCEMLVKY  180
KSDLSRPFDE ATTFLNKIEL QLSNLCTSSA NASSIRTLSD EGGASSDEDF SGGEIEVQEG  240
QQRGEDRDLK DRLMRRFGSH IGTLKLEFSK KKKKGKLPKE ARQTLFDWWS VHYKWPYPTE  300
ADKIALAEST GLDQRQINNW FINQRKRHWR PSENMQFAVM DNIAGPFFTD D*
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: First detected in torpedo stage embryos at the boundaries between the presumptive SAM and the cotyledons. Later expressed between the cotyledons and the meristem, and between the cotyledons. In seedlings, localised in stipules and at the boundaries between the SAM and the emerging primordia. Expressed at the site of lateral roots. {ECO:0000269|PubMed:16798887}.
UniprotTISSUE SPECIFICITY: Expressed predominantly in shoot apices of seedlings, and, to a lower extent, in rosette leaves. {ECO:0000269|PubMed:11311158}.
Functional Description ? help Back to Top
Source Description
UniProtPlays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269|PubMed:16798887}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPrupe.1G249600.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Seems to be repressed by AS2 and AS1 but induced by STM, CUC1 and CUC2. {ECO:0000269|PubMed:11311158, ECO:0000269|PubMed:16798887}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankEF0934910.0EF093491.1 Prunus persica knotted1-like homeobox transcription factor (KNOPE2) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007226843.20.0homeobox protein knotted-1-like 6
SwissprotQ84JS61e-139KNAT6_ARATH; Homeobox protein knotted-1-like 6
TrEMBLA0A251R3040.0A0A251R304_PRUPE; Uncharacterized protein
STRINGXP_008221855.10.0(Prunus mume)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF62034125
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G23380.11e-132KNOTTED1-like homeobox gene 6
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]