PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pp3c11_12260V3.1.p
Common NamePHYPADRAFT_175150
Organism
Physcomitrella patens
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Bryophyta; Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrella
Family LSD
Protein Properties Length: 188aa    MW: 19770 Da    PI: 8.1182
Description LSD family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pp3c11_12260V3.1.pgenomeCOSMOSSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-LSD139.59e-131943125
             zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                        C+gCrtlL YP GA++VRCalC  V
  Pp3c11_12260V3.1.p 19 CSGCRTLLVYPQGASNVRCALCSSV 43
                        **********************876 PP
2zf-LSD146.27.3e-155882125
             zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                        CggCrtlL+Y rGA+sV+C++C+tV
  Pp3c11_12260V3.1.p 58 CGGCRTLLMYMRGATSVQCSCCHTV 82
                        ************************9 PP
3zf-LSD142.11.5e-1396120125
             zf-LSD1   1 CggCrtlLsYPrGApsVRCalCdtV 25 
                         CggC+ +L+Y +GA sV+CalC++V
  Pp3c11_12260V3.1.p  96 CGGCGMTLMYAYGAQSVKCALCQFV 120
                         ***********************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
TIGRFAMsTIGR010538.6E-151646IPR005735Zinc finger, LSD1-type
PfamPF069436.5E-121943IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010533.0E-165584IPR005735Zinc finger, LSD1-type
PfamPF069431.3E-125882IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010534.8E-1193123IPR005735Zinc finger, LSD1-type
PfamPF069435.1E-1296120IPR005735Zinc finger, LSD1-type
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000006anatomyplant protoplast
PO:0025017anatomyplant spore
PO:0030003anatomyprotonema
PO:0030018anatomygametophore
Sequence ? help Back to Top
Protein Sequence    Length: 188 aa     Download sequence    Send to blast
MMPYPSMQGG QPQQGQLICS GCRTLLVYPQ GASNVRCALC SSVTQVPSHG TEMAQLVCGG  60
CRTLLMYMRG ATSVQCSCCH TVNLAMEAPQ VAHINCGGCG MTLMYAYGAQ SVKCALCQFV  120
TTITMPSMRV QLPSISQQPR PPQAHGGPPP ALTSSHTQTV VVENPMTMDE SGKLVSNVAV  180
GVSTDRR*
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Ppa.6090.0gametophore| protonema
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in cotyledons, roots, rosette leaves, stems, inflorescences and flowers. {ECO:0000269|PubMed:20456049}.
Functional Description ? help Back to Top
Source Description
UniProtNegative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269|PubMed:10550898, ECO:0000269|PubMed:11595797, ECO:0000269|PubMed:11844114, ECO:0000269|PubMed:12732715, ECO:0000269|PubMed:15347794, ECO:0000269|PubMed:16957775, ECO:0000269|PubMed:18055613, ECO:0000269|PubMed:18790826, ECO:0000269|PubMed:20456049, ECO:0000269|PubMed:21097903}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By methyl viologen. {ECO:0000269|PubMed:20456049}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024389231.11e-133protein LOL1-like
SwissprotP940774e-59LSD1_ARATH; Protein LSD1
TrEMBLA0A2K1JUH01e-131A0A2K1JUH0_PHYPA; Uncharacterized protein
STRINGPP1S11_54V6.11e-132(Physcomitrella patens)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP11461753
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G20380.73e-58LSD family protein
Publications ? help Back to Top
  1. Rensing SA, et al.
    The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants.
    Science, 2008. 319(5859): p. 64-9
    [PMID:18079367]
  2. Spedaletti V, et al.
    Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana.
    Biochemistry, 2008. 47(17): p. 4936-47
    [PMID:18393445]
  3. Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S
    PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties.
    Plant Cell Rep., 2016. 35(3): p. 527-39
    [PMID:26754794]
  4. Czarnocka W, et al.
    The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator.
    Plant Cell Environ., 2017. 40(11): p. 2644-2662
    [PMID:28555890]
  5. Bernacki MJ, et al.
    LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana.
    Physiol Plant, 2019. 165(2): p. 369-382
    [PMID:30461017]