PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

PSME_00049315-RA

Organism

Pseudotsuga menziesii

Taxonomic ID

3357

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Pseudotsuga

Family

bHLH

Protein Properties

Length: 329aa MW: 35886.3 Da PI: 6.4286

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PSME_00049315-RA	genome	PRS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	40.2	6.3e-13	155	197	7	54
HHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 7 erErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ErrRR+++N++++ Lr+++Pk K++ a++L AveY+k+L PSME_00049315-RA 155 MAERRRRKKLNDRLFMLRSVVPKV-----SKMDRASTLADAVEYMKEL 197 79*******************6.....5**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	1.7E-15	146	213	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	15.104	148	197	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	2.4E-13	154	203	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	9.3E-11	154	197	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	7.24E-12	155	201	No hit	No description
Gene3D	G3DSA:4.10.280.10	4.4E-15	155	208	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 329 aa Download sequence Send to blast
METGWTGLLD ESFSSLRGVL DEGEGEGEDD FYYTIDANGG TLEDLLGYST VYQNGSLLSN 60 VTGTVNSFHH FDSSKTTSAD TPDPQGSGDL GLLQRQDGIE AGLHKNRGKQ KLNGLIGERE 120 ADAPHSGYNK NNNGYANTPS VGRGRKNGLP AKNLMAERRR RKKLNDRLFM LRSVVPKVSK 180 MDRASTLADA VEYMKELLQR INDLHTEPMS RSSKLKPLAR TLPDFSCRMN QGHQASLLSP 240 ELKTAKVDVR TREGKSLNIH MVCSRTPDLL LSTISALDGL GLELKHAAIS CLDGFALDVF 300 QAEQSSGEDV TAEDIKALLL HTGGYVTGM

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	156	163	ERRRRKKL

Functional Description ? help Back to Top
Source	Description
UniProt	Mediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA (PubMed:18641265). Functions as a dimer with SPCH during stomatal initiation (PubMed:18641265, PubMed:28507175). {ECO:0000269\|PubMed:18641265, ECO:0000269\|PubMed:28507175}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023527076.1	1e-68	transcription factor ICE1-like
Swissprot	Q9LPW3	2e-65	SCRM2_ARATH; Transcription factor SCREAM2
TrEMBL	D5A934	2e-82	D5A934_PICSI; Uncharacterized protein
STRING	GSMUA_Achr6P08070_001	3e-68	(Musa acuminata)
STRING	XP_006417184.1	2e-67	(Eutrema salsugineum)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G12860.1	1e-67	bHLH family protein

Publications ? help Back to Top
Tarasov VA,Khadeeva NV,Mel'nik VA,Ezhova TA,Shestakov SV The Atlg12860 gene of Arabidopsis thaliana determines cathelicidin-like antimicrobial activity. Dokl. Biol. Sci., 2009. [PMID:19760875] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Emmerstorfer A, et al. Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris. Biotechnol J, 2015. 10(4): p. 623-35 [PMID:25641738] Lee HG,Seo PJ The MYB96-HHP module integrates cold and abscisic acid signaling to activate the CBF-COR pathway in Arabidopsis. Plant J., 2015. 82(6): p. 962-77 [PMID:25912720] Raissig MT,Abrash E,Bettadapur A,Vogel JP,Bergmann DC Grasses use an alternatively wired bHLH transcription factor network to establish stomatal identity. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(29): p. 8326-31 [PMID:27382177] Fu ZW,Wang YL,Lu YT,Yuan TT Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis. Plant Sci., 2016. 252: p. 282-289 [PMID:27717464] de Marcos A, et al. A Mutation in the bHLH Domain of the SPCH Transcription Factor Uncovers a BR-Dependent Mechanism for Stomatal Development. Plant Physiol., 2017. 174(2): p. 823-842 [PMID:28507175]