PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PSME_00036646-RA
Organism
Pseudotsuga menziesii
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Pseudotsuga
Family bHLH
Protein Properties Length: 324aa    MW: 35106.7 Da    PI: 4.726
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PSME_00036646-RAgenomePRSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH40.93.7e-13150192754
                       HHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
               HLH   7 erErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                       ++ErrRR+++N++++ Lr+++Pk       K++ a+iL  AveY+k+L
  PSME_00036646-RA 150 MAERRRRKKLNDRLFMLRSVVPKV-----SKMDRASILGDAVEYLKEL 192
                       79*********************6.....5****************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF474593.4E-16141207IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088815.377143192IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000108.6E-11149192IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003534.1E-14149198IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.35E-12150196No hitNo description
Gene3DG3DSA:4.10.280.101.1E-15150205IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS516718.91253324IPR002912ACT domain
CDDcd048731.03E-4261313No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008152Biological Processmetabolic process
GO:0016597Molecular Functionamino acid binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 324 aa     Download sequence    Send to blast
MAWTGLLDEN FSSIRAMLDG GEYDFYSTMD TNGGTLEALL GSSLICPDGS LLSNVGGSIN  60
TFQDLGCSIT TSADTLEGPE SIDELGLLQR RAGIESGFHK NGDVEKPNSV IGEREADVPH  120
AANNNNNNGY ANVATATRGR KNGLPAKNLM AERRRRKKLN DRLFMLRSVV PKVSKMDRAS  180
ILGDAVEYLK ELLQRINDLH SELMSSSSNS NPLAPTLPDF PGRMNQEYQA SLLNPEVQPA  240
RVEVSTTEGK ALNIHMFCSK KPGLLLSTIR ALDELGLDVK QAVINCLNGF ALDVFEAEKS  300
MGVDVTVEEI KALLLDTAGY QVGL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A2e-13145224682Transcription factor MYC2
5gnj_B2e-13145224682Transcription factor MYC2
5gnj_E2e-13145224682Transcription factor MYC2
5gnj_F2e-13145224682Transcription factor MYC2
5gnj_G2e-13145224682Transcription factor MYC2
5gnj_I2e-13145224682Transcription factor MYC2
5gnj_M2e-13145224682Transcription factor MYC2
5gnj_N2e-13145224682Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1151158ERRRRKKL
Functional Description ? help Back to Top
Source Description
UniProtMediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA (PubMed:18641265). Functions as a dimer with SPCH during stomatal initiation (PubMed:18641265, PubMed:28507175). {ECO:0000269|PubMed:18641265, ECO:0000269|PubMed:28507175}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT1226871e-164BT122687.1 Picea sitchensis clone WS0454_C09 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013461650.17e-83transcription factor ICE1 isoform X2
SwissprotQ9LPW32e-75SCRM2_ARATH; Transcription factor SCREAM2
TrEMBLD5A9341e-102D5A934_PICSI; Uncharacterized protein
STRINGXP_009625133.11e-79(Nicotiana tomentosiformis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G12860.11e-74bHLH family protein
Publications ? help Back to Top
  1. Tarasov VA,Khadeeva NV,Mel'nik VA,Ezhova TA,Shestakov SV
    The Atlg12860 gene of Arabidopsis thaliana determines cathelicidin-like antimicrobial activity.
    Dokl. Biol. Sci., 2009.
    [PMID:19760875]
  2. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Emmerstorfer A, et al.
    Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris.
    Biotechnol J, 2015. 10(4): p. 623-35
    [PMID:25641738]
  5. Lee HG,Seo PJ
    The MYB96-HHP module integrates cold and abscisic acid signaling to activate the CBF-COR pathway in Arabidopsis.
    Plant J., 2015. 82(6): p. 962-77
    [PMID:25912720]
  6. Raissig MT,Abrash E,Bettadapur A,Vogel JP,Bergmann DC
    Grasses use an alternatively wired bHLH transcription factor network to establish stomatal identity.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(29): p. 8326-31
    [PMID:27382177]
  7. Fu ZW,Wang YL,Lu YT,Yuan TT
    Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis.
    Plant Sci., 2016. 252: p. 282-289
    [PMID:27717464]
  8. de Marcos A, et al.
    A Mutation in the bHLH Domain of the SPCH Transcription Factor Uncovers a BR-Dependent Mechanism for Stomatal Development.
    Plant Physiol., 2017. 174(2): p. 823-842
    [PMID:28507175]