PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PH01004826G0040
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Bambusoideae; Arundinarodae; Arundinarieae; Arundinariinae; Phyllostachys
Family E2F/DP
Protein Properties Length: 432aa    MW: 47576 Da    PI: 4.9375
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PH01004826G0040genomeICBRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP69.73.5e-22116207771
          E2F_TDP   7 rlltqkflkllekseegivtlnevakeLvse...............................dvknkrRRiYDilNVLealnliekkekneirw 69 
                      +llt+kfl+ll+ ++ giv+ln++a++L  e                               +v  ++RRiYDi+NVLe+++liekk kn+irw
  PH01004826G0040 116 GLLTKKFLNLLKGAPGGIVDLNNAAETL--EkpqlqsygktnrkyemritspvtclrqsnlfEV--QKRRIYDITNVLEGIGLIEKKLKNNIRW 205
                      589*************************..447**************************97777..**************************** PP

          E2F_TDP  70 kg 71 
                      kg
  PH01004826G0040 206 KG 207
                      98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM013722.8E-23114207IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023197.1E-20116207IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.7E-21116144IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.63E-11165208IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.7E-21177208IPR011991Winged helix-turn-helix DNA-binding domain
CDDcd146601.64E-51218324No hitNo description
SuperFamilySSF1440741.1E-33219324No hitNo description
PfamPF164212.3E-34223322IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 432 aa     Download sequence    Send to blast
MAAAGGGTSE CAARVLLQRY QPFAPPPGEY HQFGVADGCG GEMTEAVVVR TPLKRKHDRE  60
DNETAGSNDW MMSPGYANTA SSPVPTPPSG KGSKISAKSK AAKGQKSCPQ TPLCSGLLTK  120
KFLNLLKGAP GGIVDLNNAA ETLEKPQLQS YGKTNRKYEM RITSPVTCLR QSNLFEVQKR  180
RIYDITNVLE GIGLIEKKLK NNIRWKGIHD SRPGEVSDDM SILQADIETL TLQEHSLDEQ  240
ISEMRGELRE LTEDENNQKW LYVTEDDIKS LPCFQNQTLI AIKAPHGTTL EVPDPDEVND  300
YPQRRYRIVL RSTMGPIDVY LVSQFEEMSG MGTPPRPTQT INMDSLEHPR TPLAAESNKA  360
AQMEPNIQEG LTMPPDAPTS SQDIGGMMKI VPSELDTDAD YWLLSDTGVS ITDMWKTACI  420
LVLTVFITLT F*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5tuu_B6e-192153245110Transcription factor E2F4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPH01004826G0040
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0417260.0AB041726.1 Oryza sativa OsE2F2 mRNA for E2F homolog, partial cds.
GenBankAK0592330.0AK059233.1 Oryza sativa Japonica Group cDNA clone:001-024-E10, full insert sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020177970.10.0transcription factor E2FA-like
SwissprotQ9FNY01e-106E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A446SWF50.0A0A446SWF5_TRITD; Uncharacterized protein
STRINGTraes_5BL_9F73E599F.10.0(Triticum aestivum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP62537148
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-102E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]