PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | PH01002448G0160 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Bambusoideae; Arundinarodae; Arundinarieae; Arundinariinae; Phyllostachys
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Family | E2F/DP | ||||||||
Protein Properties | Length: 397aa MW: 43961.2 Da PI: 4.738 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 86.3 | 2.3e-27 | 87 | 152 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++ll+++++gi++ln++a++L +v ++RRiYDi+NVLe+++liek+ kn+irwkg PH01002448G0160 87 RYDSSLGLLTKKFINLLKQAQDGILDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIRWKG 152 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 4.9E-29 | 84 | 154 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 9.33E-18 | 87 | 150 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 2.0E-34 | 87 | 152 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 1.7E-24 | 89 | 152 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 1.27E-47 | 162 | 268 | No hit | No description |
SuperFamily | SSF144074 | 5.75E-34 | 165 | 268 | No hit | No description |
Pfam | PF16421 | 7.3E-33 | 167 | 266 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0008284 | Biological Process | positive regulation of cell proliferation | ||||
GO:0009733 | Biological Process | response to auxin | ||||
GO:0010090 | Biological Process | trichome morphogenesis | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0051302 | Biological Process | regulation of cell division | ||||
GO:0051446 | Biological Process | positive regulation of meiotic cell cycle | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0005737 | Cellular Component | cytoplasm | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 397 aa Download sequence Send to blast |
MAKSFLSAYP LFSLKRKAAS EENDAAESSE CMITSPGFTG SPLLTPVSGK AVKASKSKNK 60 NNKAGPQTPT TNVGSPLNPP TPAGTCRYDS SLGLLTKKFI NLLKQAQDGI LDLNNAAETL 120 EVQKRRIYDI TNVLEGIGLI EKTLKNRIRW KGLDDSGVEL DNGLSVLQTE VENLNLQEQA 180 LDERISDTRE RLRGLTEDEN NQRWLYVTED DIKGLPCFQN ETLIAIKAPH GTTLEVPDPD 240 EAGDYLQRRY RIVLRSTMGP IDVYLVSQFD EKFEELGGVA TPPRHPNVPR HRPVEEFNTT 300 NAGQSSTSMD VELNVQHSQR TLQDPSASHD FGGMTRIIPS DVDYLTWKIA EVQWDQMDTD 360 VFSSEEVSTP RAHNQQPATV GEPQMQVPNM DGPVRL* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 2e-24 | 82 | 153 | 1 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | PH01002448G0160 |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | AB041725 | 0.0 | AB041725.1 Oryza sativa OsE2F1 mRNA for E2F homolog, complete cds. | |||
GenBank | AK068689 | 0.0 | AK068689.1 Oryza sativa Japonica Group cDNA clone:J013161I16, full insert sequence. | |||
GenBank | HQ858830 | 0.0 | HQ858830.1 Oryza sativa Japonica Group isolate UT1329 E2F-DP transcription factor mRNA, partial cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_025798973.1 | 0.0 | transcription factor E2FA-like isoform X2 | ||||
Swissprot | Q9FV71 | 1e-112 | E2FB_ARATH; Transcription factor E2FB | ||||
TrEMBL | A0A3L6QI95 | 0.0 | A0A3L6QI95_PANMI; Transcription factor E2FA-like | ||||
STRING | Si017108m | 0.0 | (Setaria italica) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Monocots | OGMP625 | 37 | 148 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 1e-107 | E2F transcription factor 3 |
Publications ? help Back to Top | |||
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