PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

PH01001918G0120

Organism

Phyllostachys heterocycla

Taxonomic ID

38705

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Bambusoideae; Arundinarodae; Arundinarieae; Arundinariinae; Phyllostachys

Family

E2F/DP

Protein Properties

Length: 390aa MW: 43975.9 Da PI: 5.8808

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PH01001918G0120	genome	ICBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	71	1.4e-22	95	158	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++ll+++++gi++ln++a++L ++ RiYDi+NVLe+ +liekk kn+i+wkg PH01001918G0120 95 RYDNSLGLLTKKFINLLKQAQDGILDLNKAAQTL---EM----VRIYDITNVLEGTGLIEKKLKNRIHWKG 158 689*****************************...44....4***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.1E-23	92	160	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	4.5E-25	95	158	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	1.63E-12	95	156	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	7.5E-19	97	158	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	7.99E-37	168	291	No hit	No description
SuperFamily	SSF144074	6.28E-5	170	209	No hit	No description
Pfam	PF16421	5.4E-26	173	289	IPR032198	E2F transcription factor, CC-MB domain
SuperFamily	SSF144074	1.2E-21	210	291	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 390 aa Download sequence Send to blast
MHRLLSLSLS LSLHLIVTPF FPPCLVTFSS SSRSHQSTNP TELPLYAGFL KQPRSRLAHT 60 QNLTLSCLAP CFHRRRSRGA RGSPGNPPTP ASSCRYDNSL GLLTKKFINL LKQAQDGILD 120 LNKAAQTLEM VRIYDITNVL EGTGLIEKKL KNRIHWKGLD ESGTNLDNDI SVLQTEVDNL 180 NLQEQVLDER ISEMREKVRE LTEEESNQSE MREKVRELTE EESNQRWLYL TEDDIKGLPC 240 FQNETLIAIK APHGSTLEVP DPDEAGDYLQ RRYRIVIRST MGSIDLYLVS KFEEKMEELV 300 GVATPPRHTN VAKPASMEGF RTTEAGQSSR PKEVLPNIQR IQKTPDLNAS HDFGGMTKIT 360 PDVDTDADYW LLTDGDVSIT DMWKTARIL*

Sequence ? help Back to Top

Protein Sequence Length: 390 aa Download sequence Send to blast

MHRLLSLSLS LSLHLIVTPF FPPCLVTFSS SSRSHQSTNP TELPLYAGFL KQPRSRLAHT  60
QNLTLSCLAP CFHRRRSRGA RGSPGNPPTP ASSCRYDNSL GLLTKKFINL LKQAQDGILD  120
LNKAAQTLEM VRIYDITNVL EGTGLIEKKL KNRIHWKGLD ESGTNLDNDI SVLQTEVDNL  180
NLQEQVLDER ISEMREKVRE LTEEESNQSE MREKVRELTE EESNQRWLYL TEDDIKGLPC  240
FQNETLIAIK APHGSTLEVP DPDEAGDYLQ RRYRIVIRST MGSIDLYLVS KFEEKMEELV  300
GVATPPRHTN VAKPASMEGF RTTEAGQSSR PKEVLPNIQR IQKTPDLNAS HDFGGMTKIT  360
PDVDTDADYW LLTDGDVSIT DMWKTARIL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	2e-21	90	159	2	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	PH01001918G0120

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003581217.1	1e-159	transcription factor E2FA isoform X1
Refseq	XP_010239888.1	1e-159	transcription factor E2FA isoform X2
Swissprot	Q9FNY0	1e-98	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A0A0Q3P1K0	1e-159	A0A0Q3P1K0_BRADI; Uncharacterized protein
STRING	Traes_2AL_8EC530273.1	1e-153	(Triticum aestivum)
STRING	Traes_2DL_BD8048C15.1	1e-153	(Triticum aestivum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP625	37	148

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	1e-102	E2F transcription factor 3

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]