PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PH01001688G0260
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Bambusoideae; Arundinarodae; Arundinarieae; Arundinariinae; Phyllostachys
Family E2F/DP
Protein Properties Length: 389aa    MW: 42908.3 Da    PI: 4.9345
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PH01001688G0260genomeICBRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP83.51.7e-26130195171
          E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                      r+++sL+llt+kf++lle++e+g+++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn i+wkg
  PH01001688G0260 130 RYDSSLGLLTKKFINLLERAEDGTLDLNKAAETL---EV--QKRRIYDITNVLEGVDLIEKKLKNMISWKG 195
                      6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.3E-28127196IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.09E-16130193IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.5E-33130195IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023193.3E-24132195IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440743.66E-24220326No hitNo description
PfamPF164218.8E-25220324IPR032198E2F transcription factor, CC-MB domain
CDDcd146602.98E-33220327No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 389 aa     Download sequence    Send to blast
MPPPASPAPA AAVAPPRPPP QTPAAPAQLP PRPPPPSPAA AAVPSPAPKA VGRGRPKAKA  60
PKNERENVQS EVSKGETEQG HHKDSTLGLV NGIKRPRKLK GSKHTLHVPD SHGATEGDAG  120
PSLFLSNNCR YDSSLGLLTK KFINLLERAE DGTLDLNKAA ETLEVQKRRI YDITNVLEGV  180
DLIEKKLKNM ISWKGFDMSK PKEIERQTST LKVHYTTLQT EEIESLYDED SRLDDEIMEA  240
QEKLQALMVD EDKRKWLYLS KDDINKIPRF QGSTLIAINA PHGTYVEVPD PTVDLDFLKD  300
LDFQERHYQI LLRSSMGPID CYLISSDHQE ILNPDQMAQD NLDPVVTTGS SQALYQVDSD  360
PSQAPEKIDA DYWLASDVDV SMTDTWGT*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A8e-23130196774PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPH01001688G0260
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015633977.11e-158transcription factor E2FC
SwissprotQ9FV712e-71E2FB_ARATH; Transcription factor E2FB
TrEMBLB9FD291e-159B9FD29_ORYSJ; Uncharacterized protein
STRINGBRADI5G01920.11e-162(Brachypodium distachyon)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP62537148
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.22e-73E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]