PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

PH01000197G1460

Organism

Phyllostachys heterocycla

Taxonomic ID

38705

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Bambusoideae; Arundinarodae; Arundinarieae; Arundinariinae; Phyllostachys

Family

GRF

Protein Properties

Length: 393aa MW: 42011.7 Da PI: 7.9877

Description

GRF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PH01000197G1460	genome	ICBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRC	78	9.3e-25	120	164	1	45
WRC 1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkskee 45 d+epgrCrRtDGKkWRCs+++ +++k+CErH+hrgr+rsrk++e+ PH01000197G1460 120 DPEPGRCRRTDGKKWRCSKEAAPDSKYCERHMHRGRNRSRKPVET 164 79****************************************997 PP
2	QLQ	58.3	2.3e-20	59	94	2	37
QLQ 2 aFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37 +FTaaQ ++L++Q+l+yKyL+a++PvPp+L++ i++ PH01000197G1460 59 PFTAAQYEELEQQALIYKYLVAGVPVPPDLVLLIRR 94 9*******************************9985 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00951	7.1E-11	58	94	IPR014978	Glutamine-Leucine-Glutamine, QLQ
Pfam	PF08880	3.4E-14	59	93	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51666	22.031	59	94	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51667	25.486	120	164	IPR014977	WRC domain
Pfam	PF08879	4.0E-21	121	163	IPR014977	WRC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0048366	Biological Process	leaf development
GO:0005634	Cellular Component	nucleus
GO:0005524	Molecular Function	ATP binding

Sequence ? help Back to Top
Protein Sequence Length: 393 aa Download sequence Send to blast
MAMPYASLSP AADHRSSPTA ATVSLLPFCR SSPLSAGNGG GGLGEETQMN GRWEARPAPF 60 TAAQYEELEQ QALIYKYLVA GVPVPPDLVL LIRRGLDSLA ARFYHHPALG YGSYFGKKLD 120 PEPGRCRRTD GKKWRCSKEA APDSKYCERH MHRGRNRSRK PVETQLVPQS QPPTTAAASP 180 APPLAAVASN GSNFQNHSLY PAIAGSNGSI GGGSNMSSSF ASALGSSQLH MDNAATYAAV 240 GGGTGKDLRY AAYGIRSLAD EHSQFITEAI NTSIENPWRL LPSQNSSFPL SSYRQLGALS 300 DLGQNTVSSL PKVERQPLSF FGSDFGTVDS VKQENQTLRP FFDEWPKARD SWSDLADENA 360 NLASFSATQL SISIPMASSD FSVASSRSPN GD*

Sequence ? help Back to Top

Protein Sequence Length: 393 aa Download sequence Send to blast

MAMPYASLSP AADHRSSPTA ATVSLLPFCR SSPLSAGNGG GGLGEETQMN GRWEARPAPF  60
TAAQYEELEQ QALIYKYLVA GVPVPPDLVL LIRRGLDSLA ARFYHHPALG YGSYFGKKLD  120
PEPGRCRRTD GKKWRCSKEA APDSKYCERH MHRGRNRSRK PVETQLVPQS QPPTTAAASP  180
APPLAAVASN GSNFQNHSLY PAIAGSNGSI GGGSNMSSSF ASALGSSQLH MDNAATYAAV  240
GGGTGKDLRY AAYGIRSLAD EHSQFITEAI NTSIENPWRL LPSQNSSFPL SSYRQLGALS  300
DLGQNTVSSL PKVERQPLSF FGSDFGTVDS VKQENQTLRP FFDEWPKARD SWSDLADENA  360
NLASFSATQL SISIPMASSD FSVASSRSPN GD*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that plays a role in the regulation of meristematic function in leaves, stems and inflorescences (PubMed:24532604). Transcription activator that plays a regulatory role in grain development (PubMed:26187814, PubMed:27250747, PubMed:27250749, PubMed:26936408, PubMed:27107174). Positively regulates grain size by promoting cell division and expansion, leading to increased grain length and width (PubMed:26187814, PubMed:27250747, PubMed:27250749, PubMed:26936408, PubMed:27107174). Positively regulates the expression of genes promoting cell proliferation (PubMed:26187814, PubMed:26936408). Activates the expression of expansin genes to promote cell expansion and grain size (PubMed:27250747). May promote grain size by activating brassinosteroid responses (PubMed:27250747). Component of a network formed by the microRNA396 (miRNA396), the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation (Probable). Component of the miRNA396c-GRF4-GIF1 regulatory module that plays an important role in grain size determination (Probable) (PubMed:27250747, PubMed:27250749, PubMed:27107174). {ECO:0000269\|PubMed:24532604, ECO:0000269\|PubMed:26187814, ECO:0000269\|PubMed:26936408, ECO:0000269\|PubMed:27107174, ECO:0000269\|PubMed:27250747, ECO:0000269\|PubMed:27250749, ECO:0000305\|PubMed:26187814, ECO:0000305\|PubMed:27107174, ECO:0000305\|PubMed:27250747, ECO:0000305\|PubMed:27250749}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	PH01000197G1460

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: The microRNA396c negatively regulates GRF4 at the transcriptional level. {ECO:0000269\|PubMed:26187814, ECO:0000269\|PubMed:26936408, ECO:0000269\|PubMed:27107174, ECO:0000269\|PubMed:27250747}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006647745.1	0.0	PREDICTED: LOW QUALITY PROTEIN: growth-regulating factor 4-like
Swissprot	Q6ZIK5	0.0	GRF4_ORYSJ; Growth-regulating factor 4
TrEMBL	A0A0D3F9C7	0.0	A0A0D3F9C7_9ORYZ; Uncharacterized protein
STRING	OBART02G29160.1	0.0	(Oryza barthii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP2463	34	76

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G13960.1	9e-50	growth-regulating factor 5

Publications ? help Back to Top
Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science, 2003. 301(5631): p. 376-9 [PMID:12869764] Kuijt SJ, et al. Interaction between the GROWTH-REGULATING FACTOR and KNOTTED1-LIKE HOMEOBOX families of transcription factors. Plant Physiol., 2014. 164(4): p. 1952-66 [PMID:24532604] Hu J, et al. A Rare Allele of GS2 Enhances Grain Size and Grain Yield in Rice. Mol Plant, 2015. 8(10): p. 1455-65 [PMID:26187814] Sun P, et al. OsGRF4 controls grain shape, panicle length and seed shattering in rice. J Integr Plant Biol, 2016. 58(10): p. 836-847 [PMID:26936408] Li S, et al. The OsmiR396c-OsGRF4-OsGIF1 regulatory module determines grain size and yield in rice. Plant Biotechnol. J., 2016. 14(11): p. 2134-2146 [PMID:27107174] Che R, et al. Control of grain size and rice yield by GL2-mediated brassinosteroid responses. Nat Plants, 2015. 2: p. 15195 [PMID:27250747] Duan P, et al. Regulation of OsGRF4 by OsmiR396 controls grain size and yield in rice. Nat Plants, 2015. 2: p. 15203 [PMID:27250749]