PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

PEQU_29608

Organism

Phalaenopsis equestris

Taxonomic ID

78828

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; Asparagales; Orchidaceae; Epidendroideae; Vandeae; Aeridinae; Phalaenopsis

Family

LSD

Protein Properties

Length: 155aa MW: 17065.2 Da PI: 8.4912

Description

LSD family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PEQU_29608	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-LSD1	40.5	4.4e-13	7	31	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 C+gCrt+L YPrGA sV+Ca+C+ V PEQU_29608 7 CSGCRTPLLYPRGAASVCCAICNMV 31 ***********************98 PP
2	zf-LSD1	41.4	2.4e-13	44	68	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 CggC++lL+Y rGA+ VRC++C+t+ PEQU_29608 44 CGGCQILLMYARGASTVRCSCCNTI 68 ***********************97 PP
3	zf-LSD1	45.7	1.1e-14	104	126	1	23
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCd 23 Cg+Crt+L+YP+GApsV+Ca+C PEQU_29608 104 CGHCRTTLMYPYGAPSVKCAVCR 126 **********************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
TIGRFAMs	TIGR01053	5.4E-13	4	34	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	1.4E-11	7	31	IPR005735	Zinc finger, LSD1-type
TIGRFAMs	TIGR01053	1.6E-13	41	69	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	1.2E-11	44	68	IPR005735	Zinc finger, LSD1-type
TIGRFAMs	TIGR01053	7.0E-11	101	130	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	9.4E-14	104	128	IPR005735	Zinc finger, LSD1-type

Sequence ? help Back to Top
Protein Sequence Length: 155 aa Download sequence Send to blast
MQSQLICSGC RTPLLYPRGA ASVCCAICNM VTAVPSSDRA QIICGGCQIL LMYARGASTV 60 RCSCCNTINV ARAADIILIF LLAIIILSHQ ASMAQANQVA QLSCGHCRTT LMYPYGAPSV 120 KCAVCRYITN VGVCQQFYFW RHLHTYHPIF MYFHV

Functional Description ? help Back to Top
Source	Description
UniProt	Negative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269\|PubMed:10550898, ECO:0000269\|PubMed:11595797, ECO:0000269\|PubMed:11844114, ECO:0000269\|PubMed:12732715, ECO:0000269\|PubMed:15347794, ECO:0000269\|PubMed:16957775, ECO:0000269\|PubMed:18055613, ECO:0000269\|PubMed:18790826, ECO:0000269\|PubMed:20456049, ECO:0000269\|PubMed:21097903}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By methyl viologen. {ECO:0000269\|PubMed:20456049}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020597858.1	2e-69	protein LOL3
Swissprot	P94077	2e-43	LSD1_ARATH; Protein LSD1
TrEMBL	A0A2I0VE88	5e-65	A0A2I0VE88_9ASPA; Protein LOL3
STRING	Gorai.010G246900.1	1e-49	(Gossypium raimondii)
STRING	EOY25560	8e-50	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP1347	38	124

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G20380.7	8e-45	LSD family protein

Publications ? help Back to Top
Spedaletti V, et al. Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana. Biochemistry, 2008. 47(17): p. 4936-47 [PMID:18393445] Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties. Plant Cell Rep., 2016. 35(3): p. 527-39 [PMID:26754794] Czarnocka W, et al. The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator. Plant Cell Environ., 2017. 40(11): p. 2644-2662 [PMID:28555890] Bernacki MJ, et al. LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana. Physiol Plant, 2019. 165(2): p. 369-382 [PMID:30461017]