PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PEQU_06313
Organism
Phalaenopsis equestris
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; Asparagales; Orchidaceae; Epidendroideae; Vandeae; Aeridinae; Phalaenopsis
Family GRF
Protein Properties Length: 382aa    MW: 41842.4 Da    PI: 8.1007
Description GRF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PEQU_06313genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRC79.24e-2578122145
         WRC   1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkskee 45 
                 d+epgrCrRtDGKkWRCs+++++++k+CErH+hrgr+rsrk++e+
  PEQU_06313  78 DPEPGRCRRTDGKKWRCSKDAYPDSKYCERHMHRGRNRSRKHVET 122
                 79****************************************997 PP
2QLQ61.91.7e-211752237
         QLQ  2 aFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37
                +FTa+Q+++L++Q+l++KyL+a+ PvPpeLl++i++
  PEQU_06313 17 PFTASQWEELEHQALIFKYLIAGIPVPPELLLPIRR 52
                9*********************************86 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM009512.4E-131652IPR014978Glutamine-Leucine-Glutamine, QLQ
PfamPF088804.8E-161751IPR014978Glutamine-Leucine-Glutamine, QLQ
PROSITE profilePS5166623.4771752IPR014978Glutamine-Leucine-Glutamine, QLQ
PROSITE profilePS5166725.24178122IPR014977WRC domain
PfamPF088791.4E-2079121IPR014977WRC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0048366Biological Processleaf development
GO:0005634Cellular Componentnucleus
GO:0005524Molecular FunctionATP binding
Sequence ? help Back to Top
Protein Sequence    Length: 382 aa     Download sequence    Send to blast
GQMNSTAAAV GLGCRPPFTA SQWEELEHQA LIFKYLIAGI PVPPELLLPI RRSFETMATR  60
FYQHPALGYC SYYGKKLDPE PGRCRRTDGK KWRCSKDAYP DSKYCERHMH RGRNRSRKHV  120
ETPPALSQSQ SCSTVTSLAP TSLGSSATGT GGGGAVSVAG GSCSSGSFHN LPPHSISSIY  180
HHQSTGLGAV ASSHLSIDPA SYGNFATKDF RYVHGSKTSL EERGLYSDAP ASARLLSMDS  240
SFDTSWRLLP SPATASPSSK DKDGSFLHGN YSQFQPLQQL GQVTISSFPK PNHHQHQHSF  300
FGSDYGSAES PIKTDQPLRP FFDEWPGTRD SWSDLEDDRS NRNSFSTTQL SISIPMSSSD  360
FSTTSSRSQN GELLLLIFMQ LE
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that plays a regulatory role in gibberellin-induced stem elongation. {ECO:0000250}.
UniProtTranscription activator that plays a role in the regulation of meristematic function in leaves, stems and inflorescences (PubMed:24532604). Transcription activator that plays a regulatory role in grain development (PubMed:26187814, PubMed:27250747, PubMed:27250749, PubMed:26936408, PubMed:27107174). Positively regulates grain size by promoting cell division and expansion, leading to increased grain length and width (PubMed:26187814, PubMed:27250747, PubMed:27250749, PubMed:26936408, PubMed:27107174). Positively regulates the expression of genes promoting cell proliferation (PubMed:26187814, PubMed:26936408). Activates the expression of expansin genes to promote cell expansion and grain size (PubMed:27250747). May promote grain size by activating brassinosteroid responses (PubMed:27250747). Component of a network formed by the microRNA396 (miRNA396), the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation (Probable). Component of the miRNA396c-GRF4-GIF1 regulatory module that plays an important role in grain size determination (Probable) (PubMed:27250747, PubMed:27250749, PubMed:27107174). {ECO:0000269|PubMed:24532604, ECO:0000269|PubMed:26187814, ECO:0000269|PubMed:26936408, ECO:0000269|PubMed:27107174, ECO:0000269|PubMed:27250747, ECO:0000269|PubMed:27250749, ECO:0000305|PubMed:26187814, ECO:0000305|PubMed:27107174, ECO:0000305|PubMed:27250747, ECO:0000305|PubMed:27250749}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: The microRNA396c negatively regulates GRF4 at the transcriptional level. {ECO:0000269|PubMed:26187814, ECO:0000269|PubMed:26936408, ECO:0000269|PubMed:27107174, ECO:0000269|PubMed:27250747}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020574035.10.0growth-regulating factor 4-like
RefseqXP_020574036.10.0growth-regulating factor 4-like
SwissprotQ6AWY61e-95GRF3_ORYSJ; Growth-regulating factor 3
SwissprotQ6ZIK51e-95GRF4_ORYSJ; Growth-regulating factor 4
TrEMBLA0A2I0VUZ80.0A0A2I0VUZ8_9ASPA; Growth-regulating factor 4
STRINGXP_010255823.11e-144(Nelumbo nucifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP24633476
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G13960.11e-50growth-regulating factor 5
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Kuijt SJ, et al.
    Interaction between the GROWTH-REGULATING FACTOR and KNOTTED1-LIKE HOMEOBOX families of transcription factors.
    Plant Physiol., 2014. 164(4): p. 1952-66
    [PMID:24532604]
  3. Hu J, et al.
    A Rare Allele of GS2 Enhances Grain Size and Grain Yield in Rice.
    Mol Plant, 2015. 8(10): p. 1455-65
    [PMID:26187814]
  4. Sun P, et al.
    OsGRF4 controls grain shape, panicle length and seed shattering in rice.
    J Integr Plant Biol, 2016. 58(10): p. 836-847
    [PMID:26936408]
  5. Li S, et al.
    The OsmiR396c-OsGRF4-OsGIF1 regulatory module determines grain size and yield in rice.
    Plant Biotechnol. J., 2016. 14(11): p. 2134-2146
    [PMID:27107174]
  6. Che R, et al.
    Control of grain size and rice yield by GL2-mediated brassinosteroid responses.
    Nat Plants, 2015. 2: p. 15195
    [PMID:27250747]
  7. Duan P, et al.
    Regulation of OsGRF4 by OsmiR396 controls grain size and yield in rice.
    Nat Plants, 2015. 2: p. 15203
    [PMID:27250749]