PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PDK_30s677411g002
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Arecales; Arecaceae; Coryphoideae; Phoeniceae; Phoenix
Family MYB
Protein Properties Length: 366aa    MW: 41379.6 Da    PI: 7.4496
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PDK_30s677411g002genomePDKView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding21.74.7e-0722472248
                       T-HHHHHHHHTTTS-HHHHHHHHHHHT CS
    Myb_DNA-binding 22 gtWktIartmgkgRtlkqcksrwqkyl 48
                       ++W++Ia+ +   +t+ qc+ rw++yl
  PDK_30s677411g002 22 PRWTRIAAQFK-DKTGRQCRRRWNTYL 47
                       46********9.*************97 PP

2Myb_DNA-binding45.32e-145396146
                       TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
    Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46
                       +g W++eEd ll +a k +G++ W+ Ia+ +  gRt++ +k+r+ +
  PDK_30s677411g002 53 KGGWSPEEDRLLCEAQKVYGNR-WTEIAKVVS-GRTDNAVKNRFST 96
                       688*******************.*********.**********976 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM007170.96149IPR001005SANT/Myb domain
PROSITE profilePS500906.957147IPR017877Myb-like domain
Gene3DG3DSA:1.10.10.602.0E-132155IPR009057Homeodomain-like
PfamPF002497.4E-62247IPR001005SANT/Myb domain
CDDcd001671.13E-42347No hitNo description
SuperFamilySSF466892.18E-2527108IPR009057Homeodomain-like
PROSITE profilePS5129421.49548102IPR017930Myb domain
SMARTSM007173.4E-1552100IPR001005SANT/Myb domain
PfamPF002498.4E-135396IPR001005SANT/Myb domain
CDDcd001675.76E-115697No hitNo description
Gene3DG3DSA:1.10.10.601.9E-1956101IPR009057Homeodomain-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 366 aa     Download sequence    Send to blast
MGKSMGAAVF ETIELKVFNF SPRWTRIAAQ FKDKTGRQCR RRWNTYLNAE CKKGGWSPEE  60
DRLLCEAQKV YGNRWTEIAK VVSGRTDNAV KNRFSTLCKK RAKHEALSKE NNGSCLNPNN  120
KRVIIQNGCI TAETRELSLP TKQIRYHISD LKENKISEEY LRKHGMNKDQ LRPPLAVLAQ  180
NSNIADNKTR ATFIKKDDPK LTALLQQAEL LSSLAQKVNA ENTKESLEDA WKEIQDYVAQ  240
TEESGMLSRK ISGTDFVLDD FRDLIEELMS SDSIGSTGHS NNQGNERDHQ IDDSLFDNDP  300
EVTGPHEDAQ CLGITACQEF ASPLLTTPPF QSLAEGIATP KFTSSKQQKD VHEPFFCLKH  360
ERVVVL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A5e-251110217108B-MYB
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds to DNA in promoters cis-regulatory element 5'-GGCGCGC-3' of cell cycle genes, including cyclins, cyclin-dependent kinases (CDKs), and components of the pre-replication complex (PubMed:20675570, PubMed:24687979). Binds to DNA in promoters cis-regulatory element 5'-AGCCG-3' of auxin regulated genes (e.g. PIN3 and PIN7) (PubMed:26578169). Together with FAMA and MYB88, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Represses the expression of the mitosis-inducing factors CDKB1-1 and CDKA-1, specifically required for the last guard mother cells (GMC) symmetric divisions in the stomatal pathway (PubMed:20675570, PubMed:24687979). Represses CYCA2-3 in newly formed guard cells (PubMed:21772250). Together with MYB88, regulates stomata spacing by restricting divisions late in the stomatal cell lineage thus limiting the number of GMC divisions (PubMed:11536724, PubMed:9684356, PubMed:16155180, PubMed:24123248). In collaboration with CDKB1-1 and CDKB1-2, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage (PubMed:24123248). Also involved in the shape regulation of pavement cells (PubMed:9684356). Involved in sensing and/or transducing abiotic stress (e.g. drought and salt), probably via the positive regulation of NAC019 (PubMed:21105921). Regulates female reproduction being required for entry into megasporogenesis, probably via the regulation of cell cycle genes (PubMed:22915737). Promotes histone H3K27me3 marks and represses stem cell gene expression (PubMed:24654956). Required for lateral roots (LRs) initiation via the regulation of PIN3 expression in an auxin-dependent manner (PubMed:26578065). Involved in responses to gravity stimulation in primary roots by regulating the transcription of PIN3 and PIN7 in gravity-sensing cells, thus modulating auxin asymmetric redistribution (PubMed:26578169). {ECO:0000269|PubMed:11536724, ECO:0000269|PubMed:16155180, ECO:0000269|PubMed:20675570, ECO:0000269|PubMed:21105921, ECO:0000269|PubMed:21772250, ECO:0000269|PubMed:22915737, ECO:0000269|PubMed:24123248, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24654956, ECO:0000269|PubMed:24687979, ECO:0000269|PubMed:26578065, ECO:0000269|PubMed:26578169, ECO:0000269|PubMed:9684356}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Strongly induced by auxin in a IAA14/SLR1 and ARF7 dependent manner, especially in xylem pole pericycle cells, lateral roots initiating cells. {ECO:0000269|PubMed:26578065}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008780751.10.0transcription factor MYB124 isoform X2
SwissprotQ94FL61e-94MY124_ARATH; Transcription factor MYB124
TrEMBLA0A2H3XA570.0A0A2H3XA57_PHODC; transcription factor MYB124 isoform X2
STRINGXP_008780751.10.0(Phoenix dactylifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP89033847
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G14350.21e-84MYB family protein
Publications ? help Back to Top
  1. Yang M,Sack FD
    The too many mouths and four lips mutations affect stomatal production in Arabidopsis.
    Plant Cell, 1995. 7(12): p. 2227-39
    [PMID:11536724]
  2. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Yang K, et al.
    Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis.
    J. Exp. Bot., 2014. 65(9): p. 2449-61
    [PMID:24687979]
  5. Yang M
    The FOUR LIPS (FLP) and MYB88 genes conditionally suppress the production of nonstomatal epidermal cells in Arabidopsis cotyledons.
    Am. J. Bot., 2016. 103(9): p. 1559-66
    [PMID:27620181]
  6. Xie Y, et al.
    An atypical R2R3 MYB transcription factor increases cold hardiness by CBF-dependent and CBF-independent pathways in apple.
    New Phytol., 2018. 218(1): p. 201-218
    [PMID:29266327]