PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Pbr041158.1

Organism

Pyrus bretschneideri

Taxonomic ID

225117

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus

Family

NAC

Protein Properties

Length: 726aa MW: 78690.8 Da PI: 6.4617

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pbr041158.1	genome	CPETR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	166.8	7.4e-52	36	163	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskk 96 l+pGfrFhPtdeelv +yLk+kv +k++++ ++i+evdiyk+ePwdL k ++k++++e+yfFs d+ky +g r nrat++gyWkatg+d++v++ + Pbr041158.1 36 LAPGFRFHPTDEELVIYYLKRKVCRKPFKF-NAISEVDIYKSEPWDLAdKsSLKSRDQEYYFFSALDRKYGNGARMNRATNQGYWKATGNDRAVKH-N 131 579************************9.89**********75347888999**********************************.9 PP NAM 97 gelvglkktLvfykgrapkgektdWvmheyrl 128 + +vg+kktLvf++grap+g++t+Wvmheyrl Pbr041158.1 132 DINVGMKKTLVFHSGRAPDGKRTNWVMHEYRL 163 99**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	1.7E-58	34	188	IPR003441	NAC domain
PROSITE profile	PS51005	55.66	36	188	IPR003441	NAC domain
Pfam	PF02365	2.7E-26	38	163	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009555	Biological Process	pollen development
GO:0010228	Biological Process	vegetative to reproductive phase transition of meristem
GO:0005730	Cellular Component	nucleolus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 726 aa Download sequence Send to blast
MGREADLQII PSAAAAVIAV AAPIDPPTPA PAPTALAPGF RFHPTDEELV IYYLKRKVCR 60 KPFKFNAISE VDIYKSEPWD LADKSSLKSR DQEYYFFSAL DRKYGNGARM NRATNQGYWK 120 ATGNDRAVKH NDINVGMKKT LVFHSGRAPD GKRTNWVMHE YRLVDEVFEK AGLGAIQDAF 180 VLCRVFHKSN IGPPNGHRYA PFVEEEWDDD DKLTLVPGQE TRSVAVVSRD AFVVGNGHAA 240 CSEQNDYAAR SEQKVHAARS EQKVHAARSE QNDYVARSEQ KVHAARSEQN DYVARSEQKV 300 HAARSEQNDY AAHSEQKVHA ARGEQNGHAA YIKGNGHATY IGGNGHAGYI GGNGHAAYIG 360 GNGHAAYIGG NGQAAYNGEN GHGTSVERNG HGISMEGIDH GTSVKGTGHG TEGNGHGTSV 420 KRYGHVTSVE GSGHVTSEGS GHVTSVEGNG QVTSVKGNGH GISVKGNVVE GIGHGTIIVV 480 DDNGTTNEGN CHETGTAGNG HSAPTAENNI EQDTQAISTA IVVVPELPTE NQTVLPPCKT 540 ERTDDYPMTC VVNREERLDD YPSPGPDDAQ PLLTLFNRQP GQLRQYKRRR HNESNSNHSN 600 ASEISSGMTH DPCSSTTTTA STEASMTTTT RNFLSALVEY QLLESLEPKD TTPAPPPELN 660 AALMESSVPT SCLKYIETLQ TEIHKISIER ETLKFEMMSA QAMINILQAR IDLLNKENED 720 LKRKV*

Sequence ? help Back to Top

Protein Sequence Length: 726 aa Download sequence Send to blast

MGREADLQII PSAAAAVIAV AAPIDPPTPA PAPTALAPGF RFHPTDEELV IYYLKRKVCR  60
KPFKFNAISE VDIYKSEPWD LADKSSLKSR DQEYYFFSAL DRKYGNGARM NRATNQGYWK  120
ATGNDRAVKH NDINVGMKKT LVFHSGRAPD GKRTNWVMHE YRLVDEVFEK AGLGAIQDAF  180
VLCRVFHKSN IGPPNGHRYA PFVEEEWDDD DKLTLVPGQE TRSVAVVSRD AFVVGNGHAA  240
CSEQNDYAAR SEQKVHAARS EQKVHAARSE QNDYVARSEQ KVHAARSEQN DYVARSEQKV  300
HAARSEQNDY AAHSEQKVHA ARGEQNGHAA YIKGNGHATY IGGNGHAGYI GGNGHAAYIG  360
GNGHAAYIGG NGQAAYNGEN GHGTSVERNG HGISMEGIDH GTSVKGTGHG TEGNGHGTSV  420
KRYGHVTSVE GSGHVTSEGS GHVTSVEGNG QVTSVKGNGH GISVKGNVVE GIGHGTIIVV  480
DDNGTTNEGN CHETGTAGNG HSAPTAENNI EQDTQAISTA IVVVPELPTE NQTVLPPCKT  540
ERTDDYPMTC VVNREERLDD YPSPGPDDAQ PLLTLFNRQP GQLRQYKRRR HNESNSNHSN  600
ASEISSGMTH DPCSSTTTTA STEASMTTTT RNFLSALVEY QLLESLEPKD TTPAPPPELN  660
AALMESSVPT SCLKYIETLQ TEIHKISIER ETLKFEMMSA QAMINILQAR IDLLNKENED  720
LKRKV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3swm_A	1e-45	35	190	19	170	NAC domain-containing protein 19
3swm_B	1e-45	35	190	19	170	NAC domain-containing protein 19
3swm_C	1e-45	35	190	19	170	NAC domain-containing protein 19
3swm_D	1e-45	35	190	19	170	NAC domain-containing protein 19
3swp_A	1e-45	35	190	19	170	NAC domain-containing protein 19
3swp_B	1e-45	35	190	19	170	NAC domain-containing protein 19
3swp_C	1e-45	35	190	19	170	NAC domain-containing protein 19
3swp_D	1e-45	35	190	19	170	NAC domain-containing protein 19
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor that binds to the motif 5'-(C/T)A(C/A)G-3' in the promoter of target genes (PubMed:25578968). Binds also to the 5'-CTTGNNNNNCAAG-3' consensus sequence in chromatin (PubMed:26617990). Can bind to the mitochondrial dysfunction motif (MDM) present in the upstream regions of mitochondrial dysfunction stimulon (MDS) genes involved in mitochondrial retrograde regulation (MRR) (PubMed:24045019). Together with NAC050 and JMJ14, regulates gene expression and flowering time by associating with the histone demethylase JMJ14, probably by the promotion of RNA-mediated gene silencing (PubMed:25578968, PubMed:26617990). Regulates siRNA-dependent post-transcriptional gene silencing (PTGS) through SGS3 expression modulation (PubMed:28207953). Required during pollen development (PubMed:19237690). {ECO:0000269\|PubMed:19237690, ECO:0000269\|PubMed:24045019, ECO:0000269\|PubMed:25578968, ECO:0000269\|PubMed:26617990, ECO:0000269\|PubMed:28207953}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00612	ChIP-seq	Transfer from AT3G10490	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Pbr041158.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by type III effector proteins (TTEs) secreted by the pathogenic bacteria P.syringae pv. tomato DC3000 during basal defense. {ECO:0000269\|PubMed:16553893}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	-	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009346645.1	0.0	PREDICTED: filaggrin-2-like isoform X1
Swissprot	Q9SQY0	1e-94	NAC52_ARATH; NAC domain containing protein 52
TrEMBL	A0A498KHB8	0.0	A0A498KHB8_MALDO; Uncharacterized protein
STRING	XP_009346645.1	0.0	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8189	32	41

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G10490.1	2e-93	NAC domain containing protein 52

Publications ? help Back to Top
Higgins JD,Ferdous M,Osman K,Franklin FC The RecQ helicase AtRECQ4A is required to remove inter-chromosomal telomeric connections that arise during meiotic recombination in Arabidopsis. Plant J., 2011. 65(3): p. 492-502 [PMID:21265901] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zhang S, et al. C-terminal domains of a histone demethylase interact with a pair of transcription factors and mediate specific chromatin association. Cell Discov, 2019. [PMID:26617990] Butel N,Le Masson I,Bouteiller N,Vaucheret H,Elmayan T sgs1: a neomorphic nac52 allele impairing post-transcriptional gene silencing through SGS3 downregulation. Plant J., 2017. 90(3): p. 505-519 [PMID:28207953] Elmayan T, et al. Arabidopsis mutants impaired in cosuppression. Plant Cell, 1998. 10(10): p. 1747-58 [PMID:9761800]