PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pbr040796.1
Organism
Pyrus bretschneideri
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus
Family NAC
Protein Properties Length: 648aa    MW: 70028.5 Da    PI: 5.5451
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pbr040796.1genomeCPETRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM167.15.9e-52351621128
          NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskk 96 
                  l+pGfrFhPtdeelv +yLk+kv +k++++ ++i+evdiyk+ePwdL  k ++k++++e+yfFs  d+ky +g r nrat++gyWkatg+d++v++ +
  Pbr040796.1  35 LAPGFRFHPTDEELVIYYLKRKVCRKPFKF-NAISEVDIYKSEPWDLAdKsSLKSRDQEYYFFSALDRKYGNGARMNRATNQGYWKATGNDRAVKH-N 130
                  579**************************9.89**************75347888999**************************************.9 PP

          NAM  97 gelvglkktLvfykgrapkgektdWvmheyrl 128
                  + +vg+kktLvf++grap+g++t+Wvmheyrl
  Pbr040796.1 131 DIVVGMKKTLVFHSGRAPDGKRTNWVMHEYRL 162
                  99****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019414.32E-5933187IPR003441NAC domain
PROSITE profilePS5100556.03835187IPR003441NAC domain
PfamPF023652.3E-2637162IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009555Biological Processpollen development
GO:0010228Biological Processvegetative to reproductive phase transition of meristem
GO:0005730Cellular Componentnucleolus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 648 aa     Download sequence    Send to blast
MGREADLQII ASAAADVAVA APLVPPTLPP APTALAPGFR FHPTDEELVI YYLKRKVCRK  60
PFKFNAISEV DIYKSEPWDL ADKSSLKSRD QEYYFFSALD RKYGNGARMN RATNQGYWKA  120
TGNDRAVKHN DIVVGMKKTL VFHSGRAPDG KRTNWVMHEY RLVDEVFEKA GLGAIQDAFV  180
LCRVFHKSNI GPPNGHRYAP FVEEEWDDDD KLTLVPGQET RTVAVVSRDA FVVGNGHAAC  240
SEQNDYADGS EQKVHAARSE QNGLAAYIRG NGHAAYTGGN GHAAHIGGNG HAVCIGGNGQ  300
AAYNGENGHG TSVEGNGHGT SMEGIAHGTS VEGTGHGTSV KGSGRSTSVE GGGRGTYVER  360
NGHGTSVEEN DHGISVEENG HGISVEGNIV EGIGHGAIIV VDDNGTTNEG DCHETCTAGN  420
GHSVPSAEKE NNIEQDTQAI SKAIVVVPEL PAENQTVLPP CKTEKTDDYP MTCVVNREER  480
LDDFPSPGPD DAQPLLTLFN RQPGQLRQYK RRRHNDSNSN HSNASEISSG MTHDPCSSTT  540
TTASTEASMT TTRNFLSALV EYQLLESLEP KDTTPAPPPE LNAALMESSV PTSCLKYIET  600
LQTEIHKISI ERETLKFEMM SAQAMINILQ ARIDLLNKEN EDLKKKV*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3swm_A3e-46241899170NAC domain-containing protein 19
3swm_B3e-46241899170NAC domain-containing protein 19
3swm_C3e-46241899170NAC domain-containing protein 19
3swm_D3e-46241899170NAC domain-containing protein 19
3swp_A3e-46241899170NAC domain-containing protein 19
3swp_B3e-46241899170NAC domain-containing protein 19
3swp_C3e-46241899170NAC domain-containing protein 19
3swp_D3e-46241899170NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional repressor that binds to the motif 5'-(C/T)A(C/A)G-3' in the promoter of target genes (PubMed:25578968). Binds also to the 5'-CTTGNNNNNCAAG-3' consensus sequence in chromatin (PubMed:26617990). Can bind to the mitochondrial dysfunction motif (MDM) present in the upstream regions of mitochondrial dysfunction stimulon (MDS) genes involved in mitochondrial retrograde regulation (MRR) (PubMed:24045019). Together with NAC050 and JMJ14, regulates gene expression and flowering time by associating with the histone demethylase JMJ14, probably by the promotion of RNA-mediated gene silencing (PubMed:25578968, PubMed:26617990). Regulates siRNA-dependent post-transcriptional gene silencing (PTGS) through SGS3 expression modulation (PubMed:28207953). Required during pollen development (PubMed:19237690). {ECO:0000269|PubMed:19237690, ECO:0000269|PubMed:24045019, ECO:0000269|PubMed:25578968, ECO:0000269|PubMed:26617990, ECO:0000269|PubMed:28207953}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00612ChIP-seqTransfer from AT3G10490Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapPbr040796.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by type III effector proteins (TTEs) secreted by the pathogenic bacteria P.syringae pv. tomato DC3000 during basal defense. {ECO:0000269|PubMed:16553893}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMap-Retrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009361440.10.0PREDICTED: uncharacterized protein LOC103951718
SwissprotQ9SQY05e-95NAC52_ARATH; NAC domain containing protein 52
TrEMBLA0A498JCB00.0A0A498JCB0_MALDO; Uncharacterized protein
STRINGXP_009361440.10.0(Pyrus x bretschneideri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF81893241
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G10490.13e-94NAC domain containing protein 52
Publications ? help Back to Top
  1. Higgins JD,Ferdous M,Osman K,Franklin FC
    The RecQ helicase AtRECQ4A is required to remove inter-chromosomal telomeric connections that arise during meiotic recombination in Arabidopsis.
    Plant J., 2011. 65(3): p. 492-502
    [PMID:21265901]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Zhang S, et al.
    C-terminal domains of a histone demethylase interact with a pair of transcription factors and mediate specific chromatin association.
    Cell Discov, 2019.
    [PMID:26617990]
  4. Butel N,Le Masson I,Bouteiller N,Vaucheret H,Elmayan T
    sgs1: a neomorphic nac52 allele impairing post-transcriptional gene silencing through SGS3 downregulation.
    Plant J., 2017. 90(3): p. 505-519
    [PMID:28207953]
  5. Elmayan T, et al.
    Arabidopsis mutants impaired in cosuppression.
    Plant Cell, 1998. 10(10): p. 1747-58
    [PMID:9761800]