PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Pbr031206.1

Organism

Pyrus bretschneideri

Taxonomic ID

225117

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus

Family

TCP

Protein Properties

Length: 346aa MW: 37828.2 Da PI: 6.9105

Description

TCP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pbr031206.1	genome	CPETR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	TCP	108.7	8.8e-34	22	133	2	112
TCP 2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgt.....................ssssaseceaess 78 +g+kdrhsk++T++g+RdRRvRlsa++a++f+d+qd+LG+d++sk+++WL+++ak +i++l+++ s+++++e Pbr031206.1 22 TGRKDRHSKVYTAKGPRDRRVRLSAHTAIQFYDVQDRLGYDRPSKAVDWLIRKAKSSIDKLAELppwhpittsnhtaeaddpfrsSNPNPNE------ 113 79**************************************************************7777665544444444433331111111...... PP TCP 79 sssasnsssg..............kaaksaakskksqksaasalnlak 112 n++ Pbr031206.1 114 ---------MviaaaepqsessagY-------------------NFNF 133 .........1211111111112221...................2221 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF03634	2.7E-30	22	138	IPR005333	Transcription factor, TCP
PROSITE profile	PS51369	32.808	24	82	IPR017887	Transcription factor TCP subgroup

Sequence ? help Back to Top
Protein Sequence Length: 346 aa Download sequence Send to blast
MGMKGCGGEI VQVQGGHIVR STGRKDRHSK VYTAKGPRDR RVRLSAHTAI QFYDVQDRLG 60 YDRPSKAVDW LIRKAKSSID KLAELPPWHP ITTSNHTAEA DDPFRSSNPN PNEMVIAAAE 120 PQSESSAGYN FNFELHRQRQ SDNDSNFNIP PSLDSDNIAD TMKSFFPTNT SSNAAAASSV 180 VDFQSYAPDP HLISTTTQDL GLSLHSFQDQ SLNIHHNHTH TQQSSQTLFA AAMGIGLDSS 240 SYQRMVAWSN ENRGLDGGFV FNSHSHSYAQ PQPHHHGGTL QSSFTPSVSA RTWQQQQQHS 300 SIFGTRFGAS DGSSPVFCIQ GEEAENGVVS DRTASTSSPN STRQL*

Sequence ? help Back to Top

Protein Sequence Length: 346 aa Download sequence Send to blast

MGMKGCGGEI VQVQGGHIVR STGRKDRHSK VYTAKGPRDR RVRLSAHTAI QFYDVQDRLG  60
YDRPSKAVDW LIRKAKSSID KLAELPPWHP ITTSNHTAEA DDPFRSSNPN PNEMVIAAAE  120
PQSESSAGYN FNFELHRQRQ SDNDSNFNIP PSLDSDNIAD TMKSFFPTNT SSNAAAASSV  180
VDFQSYAPDP HLISTTTQDL GLSLHSFQDQ SLNIHHNHTH TQQSSQTLFA AAMGIGLDSS  240
SYQRMVAWSN ENRGLDGGFV FNSHSHSYAQ PQPHHHGGTL QSSFTPSVSA RTWQQQQQHS  300
SIFGTRFGAS DGSSPVFCIQ GEEAENGVVS DRTASTSSPN STRQL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5zkt_A	2e-22	29	82	1	54	Putative transcription factor PCF6
5zkt_B	2e-22	29	82	1	54	Putative transcription factor PCF6
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor playing a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164) (PubMed:12931144, PubMed:17307931). Required during early steps of embryogenesis (PubMed:15634699). Participates in ovule develpment (PubMed:25378179). Activates LOX2 expression by binding to the 5'-GGACCA-3' motif found in its promoter (PubMed:18816164). {ECO:0000269\|PubMed:12931144, ECO:0000269\|PubMed:15634699, ECO:0000269\|PubMed:17307931, ECO:0000269\|PubMed:18816164, ECO:0000269\|PubMed:25378179}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Pbr031206.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by the miRNA miR-JAW/miR319 (PubMed:12931144, PubMed:18816164). {ECO:0000269\|PubMed:12931144, ECO:0000269\|PubMed:18816164}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KM501064	0.0	KM501064.1 Malus domestica TCP domain-containing protein 4 mRNA, partial cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009357156.1	0.0	PREDICTED: transcription factor TCP4-like
Swissprot	Q8LPR5	2e-64	TCP4_ARATH; Transcription factor TCP4
TrEMBL	A0A498JAJ5	0.0	A0A498JAJ5_MALDO; Uncharacterized protein
STRING	XP_009357156.1	0.0	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1163	34	105

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G15030.3	6e-63	TCP family protein

Publications ? help Back to Top
Schommer C, et al. Control of jasmonate biosynthesis and senescence by miR319 targets. PLoS Biol., 2008. 6(9): p. e230 [PMID:18816164] Ju Y, et al. Arabidopsis JINGUBANG Is a Negative Regulator of Pollen Germination That Prevents Pollination in Moist Environments. Plant Cell, 2016. 28(9): p. 2131-2146 [PMID:27468890] Challa KR,Aggarwal P,Nath U Activation of YUCCA5 by the Transcription Factor TCP4 Integrates Developmental and Environmental Signals to Promote Hypocotyl Elongation in Arabidopsis. Plant Cell, 2016. 28(9): p. 2117-2130 [PMID:27597774] Alvarez JP,Furumizu C,Efroni I,Eshed Y,Bowman JL Active suppression of a leaf meristem orchestrates determinate leaf growth. Elife, 2017. [PMID:27710768] Li J, et al. RABBIT EARS regulates the transcription of TCP4 during petal development in Arabidopsis. J. Exp. Bot., 2016. 67(22): p. 6473-6480 [PMID:27838638] Sun X, et al. Activation of secondary cell wall biosynthesis by miR319-targeted TCP4 transcription factor. Plant Biotechnol. J., 2017. 15(10): p. 1284-1294 [PMID:28233945] Kubota A, et al. TCP4-dependent induction of CONSTANS transcription requires GIGANTEA in photoperiodic flowering in Arabidopsis. PLoS Genet., 2017. 13(6): p. e1006856 [PMID:28628608] Koyama T,Sato F,Ohme-Takagi M Roles of miR319 and TCP Transcription Factors in Leaf Development. Plant Physiol., 2017. 175(2): p. 874-885 [PMID:28842549] Bresso EG,Chorostecki U,Rodriguez RE,Palatnik JF,Schommer C Spatial Control of Gene Expression by miR319-Regulated TCP Transcription Factors in Leaf Development. Plant Physiol., 2018. 176(2): p. 1694-1708 [PMID:29133375] Vadde BVL,Challa KR,Nath U The TCP4 transcription factor regulates trichome cell differentiation by directly activating GLABROUS INFLORESCENCE STEMS in Arabidopsis thaliana. Plant J., 2018. 93(2): p. 259-269 [PMID:29165850] Challa KR,Rath M,Nath U The CIN-TCP transcription factors promote commitment to differentiation in Arabidopsis leaf pavement cells via both auxin-dependent and independent pathways. PLoS Genet., 2019. 15(2): p. e1007988 [PMID:30742619]