PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Pbr030944.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus
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Family | bHLH | ||||||||
Protein Properties | Length: 454aa MW: 50766.8 Da PI: 4.8999 | ||||||||
Description | bHLH family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | HLH | 37.9 | 3.3e-12 | 234 | 285 | 1 | 55 |
CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +r++h ++Er+RR+++N+ + Lr+l+P + + ++ + a+i A+e++++L+ Pbr030944.1 234 QRMTHIAVERNRRKQMNEHLRVLRSLMPGS---YVQRGDQASIIGGAIEFVRELE 285 79****************************...9*****************9995 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
CDD | cd00083 | 4.26E-13 | 232 | 289 | No hit | No description |
Gene3D | G3DSA:4.10.280.10 | 1.7E-13 | 232 | 288 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
SuperFamily | SSF47459 | 1.7E-16 | 233 | 301 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
PROSITE profile | PS50888 | 15.428 | 233 | 284 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Pfam | PF00010 | 1.5E-9 | 234 | 285 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
SMART | SM00353 | 3.4E-9 | 239 | 290 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
CDD | cd04873 | 0.00834 | 378 | 442 | No hit | No description |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0010377 | Biological Process | guard cell fate commitment | ||||
GO:0045597 | Biological Process | positive regulation of cell differentiation | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0051782 | Biological Process | negative regulation of cell division | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0046983 | Molecular Function | protein dimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 454 aa Download sequence Send to blast |
MLFFCSDDFE TLQAFMPPSN FNSLDYTLDH HQEDQQMLKS RVDETNSSDN NNGMVNYLMY 60 NHHQLQQQQQ QQQQQQISTQ LAPAGFCGST STSFDKLSFA DVMQFADFGQ KLALNQTKIS 120 EEEPAIDPVY FLKFPVLNDK LDNNQDQSIS LMVPQAEERF TGLGEEDKTK SMEEEQDEEG 180 RVSGSNNSVQ KLHFLGEDHQ NNPRGGGVQP EPAAAKNKRK RPRTTKTTQE VESQRMTHIA 240 VERNRRKQMN EHLRVLRSLM PGSYVQRGDQ ASIIGGAIEF VRELEQLLQC LESQKRRRLL 300 GEAPPRQVGD SATAAAMAVQ AAEGGGGPLI FPAANLSINN PNDPIKFVDY ETGLREETAE 360 NKSCFADVEV KVLGFDAMIK ILSQRRPGQL IKAIAALEDL QLNILHTNIT TIEQTVLYSF 420 NVKVGSESRF TAEDIASSVQ QIFSFIHANT ASM* |
Nucleic Localization Signal ? help Back to Top | |||
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No. | Start | End | Sequence |
1 | 234 | 245 | RMTHIAVERNRR |
2 | 294 | 298 | KRRRL |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator (PubMed:17088607, PubMed:17183265, PubMed:17183267). Together with MYB88 and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Together with SPCH and MUTE, regulates the stomata formation. Required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. Mediates the formation of stomata (PubMed:17088607, PubMed:17183265, PubMed:17183267). Prevents histone H3K27me3 marks and derepresses stem cell gene expression (PubMed:24654956). {ECO:0000269|PubMed:17088607, ECO:0000269|PubMed:17183265, ECO:0000269|PubMed:17183267, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24654956}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | Pbr030944.1 |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Inhibited by low relative humidity (LRH) via epigenetic CG methylation, thus leading to a reduced stomatal index. {ECO:0000269|PubMed:22442411}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_018506984.1 | 0.0 | PREDICTED: transcription factor FAMA isoform X1 | ||||
Swissprot | Q56YJ8 | 1e-144 | FAMA_ARATH; Transcription factor FAMA | ||||
TrEMBL | A0A498K498 | 0.0 | A0A498K498_MALDO; Uncharacterized protein | ||||
STRING | XP_009374601.1 | 0.0 | (Pyrus x bretschneideri) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF10489 | 33 | 40 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G24140.1 | 1e-123 | bHLH family protein |