PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pbr025320.2
Organism
Pyrus bretschneideri
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus
Family bHLH
Protein Properties Length: 375aa    MW: 41243.7 Da    PI: 7.0016
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pbr025320.2genomeCPETRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH33.38.5e-11327373455
                  HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
          HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                  +h e+Er+RR++ N+++  Lr ++P+ +      K +Ka+ L  A+ YI+ +q
  Pbr025320.2 327 NHVEAERQRREKPNQSYYALRAVVPNiS------KIDKASLLGDAITYISRMQ 373
                  799***********************66......****************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142152.7E-2349180IPR025610Transcription factor MYC/MYB N-terminal
SuperFamilySSF474591.57E-12322373IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088814.532323372IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.107.0E-11326373IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.32E-11326373No hitNo description
PfamPF000103.1E-8327373IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003533.4E-6329374IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 375 aa     Download sequence    Send to blast
MGEKFWVNEE DKVVMESVLG TEACQFLISL ASENVLSELI RPPGKLGVQQ GLCQLVKGSN  60
WNYFIFWQAV SKKSGGSALI WGDGHCRDTK GGGAGDVNSS RDGSLEAMQK KEEVKKWVLE  120
KLHACFGGLN GDIYARRLDG VSDVEMFHLT SMCYAFQLDS ISHCGPGESS KSGKSIWVSD  180
AGVVGLGSVK STSEKQSYVD MVRSAFGESS PIQAKTFPMI FGRELSLGGP KSQSVNISFT  240
PKIEEDFAFP PEPFELQSAG TSNGCRREDS EVKLFPQMNQ MMVDGFNVQT RVSSSELLKD  300
ESSAQIDERK PRKRGRKPAN GREEALNHVE AERQRREKPN QSYYALRAVV PNISKIDKAS  360
LLGDAITYIS RMQL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A3e-22321373254Transcription factor MYC2
5gnj_B3e-22321373254Transcription factor MYC2
5gnj_E3e-22321373254Transcription factor MYC2
5gnj_F3e-22321373254Transcription factor MYC2
5gnj_G3e-22321373254Transcription factor MYC2
5gnj_I3e-22321373254Transcription factor MYC2
5gnj_M3e-22321373254Transcription factor MYC2
5gnj_N3e-22321373254Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1308316RKPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPbr025320.2
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009354912.10.0PREDICTED: transcription factor bHLH3-like
RefseqXP_009354914.10.0PREDICTED: transcription factor bHLH3-like
SwissprotA0A3Q7H2161e-115MTB3_SOLLC; Transcription factor MTB3
TrEMBLA0A498JXX30.0A0A498JXX3_MALDO; Uncharacterized protein
STRINGXP_009354912.10.0(Pyrus x bretschneideri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF82633445
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16430.14e-97bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]