PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Pbr022498.1

Organism

Pyrus bretschneideri

Taxonomic ID

225117

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus

Family

TCP

Protein Properties

Length: 352aa MW: 38301.5 Da PI: 6.4584

Description

TCP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pbr022498.1	genome	CPETR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	TCP	111.8	9.6e-35	22	140	2	119
TCP 2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgt.....................ssssasec.eaes 77 +g+kdrhski+T++g+RdRRvRlsa++a++f+d+qd+LG+d++sk+++WL+++ak +i++l+++ s+++++++ Pbr022498.1 22 TGRKDRHSKIYTAKGPRDRRVRLSAHTAIQFYDVQDRLGYDRPSKAVDWLIKKAKSSIDKLVELppwhpittsnhaaeaddpfrsSNPNPNDMaI--- 116 79**************************************************************7777666555555544444432222222221... PP TCP 78 ssssasnsssgkaaksaakskksqksaasalnlakesrakar 119 ++q++++s n++ e r + + Pbr022498.1 117 ------------------AAAEQQSESSSSYNFNFELRRQRQ 140 ..................222222222222333333332222 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF03634	5.3E-31	22	138	IPR005333	Transcription factor, TCP
PROSITE profile	PS51369	32.599	24	82	IPR017887	Transcription factor TCP subgroup

Sequence ? help Back to Top
Protein Sequence Length: 352 aa Download sequence Send to blast
MGMEGCGGEI VEVQGGHIVR STGRKDRHSK IYTAKGPRDR RVRLSAHTAI QFYDVQDRLG 60 YDRPSKAVDW LIKKAKSSID KLVELPPWHP ITTSNHAAEA DDPFRSSNPN PNDMAIAAAE 120 QQSESSSSYN FNFELRRQRQ SDNDSNFNIP PSLDSDNIAD TMKSFFPTNT SSNAAAASSV 180 DDFRSYPTDP HLISATTQDL GLSLLSFQDQ GLNIHHNHTH SHTQQPSQAL FAAAAATGFD 240 SSSYQRMVAW SNENRGLDGG FVFNSHSHSY AQPQPHNHGG DGNHGSTLQS SFTPSVSTSA 300 WQQQHSSIFG TRFGTSDGTS PAFCIQGDEA ENGVISDRPS STSSLNSTRQ L*

Sequence ? help Back to Top

Protein Sequence Length: 352 aa Download sequence Send to blast

MGMEGCGGEI VEVQGGHIVR STGRKDRHSK IYTAKGPRDR RVRLSAHTAI QFYDVQDRLG  60
YDRPSKAVDW LIKKAKSSID KLVELPPWHP ITTSNHAAEA DDPFRSSNPN PNDMAIAAAE  120
QQSESSSSYN FNFELRRQRQ SDNDSNFNIP PSLDSDNIAD TMKSFFPTNT SSNAAAASSV  180
DDFRSYPTDP HLISATTQDL GLSLLSFQDQ GLNIHHNHTH SHTQQPSQAL FAAAAATGFD  240
SSSYQRMVAW SNENRGLDGG FVFNSHSHSY AQPQPHNHGG DGNHGSTLQS SFTPSVSTSA  300
WQQQHSSIFG TRFGTSDGTS PAFCIQGDEA ENGVISDRPS STSSLNSTRQ L*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5zkt_A	2e-22	29	82	1	54	Putative transcription factor PCF6
5zkt_B	2e-22	29	82	1	54	Putative transcription factor PCF6
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor playing a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164) (PubMed:12931144, PubMed:17307931). Required during early steps of embryogenesis (PubMed:15634699). Participates in ovule develpment (PubMed:25378179). Activates LOX2 expression by binding to the 5'-GGACCA-3' motif found in its promoter (PubMed:18816164). {ECO:0000269\|PubMed:12931144, ECO:0000269\|PubMed:15634699, ECO:0000269\|PubMed:17307931, ECO:0000269\|PubMed:18816164, ECO:0000269\|PubMed:25378179}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Pbr022498.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by the miRNA miR-JAW/miR319 (PubMed:12931144, PubMed:18816164). {ECO:0000269\|PubMed:12931144, ECO:0000269\|PubMed:18816164}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KM501064	0.0	KM501064.1 Malus domestica TCP domain-containing protein 4 mRNA, partial cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009354282.1	0.0	PREDICTED: transcription factor TCP4-like
Swissprot	Q8LPR5	2e-62	TCP4_ARATH; Transcription factor TCP4
TrEMBL	A0A498HHB9	0.0	A0A498HHB9_MALDO; Uncharacterized protein
STRING	XP_009354282.1	0.0	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1163	34	105

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G15030.3	7e-61	TCP family protein

Publications ? help Back to Top
Schommer C, et al. Control of jasmonate biosynthesis and senescence by miR319 targets. PLoS Biol., 2008. 6(9): p. e230 [PMID:18816164] Ju Y, et al. Arabidopsis JINGUBANG Is a Negative Regulator of Pollen Germination That Prevents Pollination in Moist Environments. Plant Cell, 2016. 28(9): p. 2131-2146 [PMID:27468890] Challa KR,Aggarwal P,Nath U Activation of YUCCA5 by the Transcription Factor TCP4 Integrates Developmental and Environmental Signals to Promote Hypocotyl Elongation in Arabidopsis. Plant Cell, 2016. 28(9): p. 2117-2130 [PMID:27597774] Alvarez JP,Furumizu C,Efroni I,Eshed Y,Bowman JL Active suppression of a leaf meristem orchestrates determinate leaf growth. Elife, 2017. [PMID:27710768] Li J, et al. RABBIT EARS regulates the transcription of TCP4 during petal development in Arabidopsis. J. Exp. Bot., 2016. 67(22): p. 6473-6480 [PMID:27838638] Sun X, et al. Activation of secondary cell wall biosynthesis by miR319-targeted TCP4 transcription factor. Plant Biotechnol. J., 2017. 15(10): p. 1284-1294 [PMID:28233945] Kubota A, et al. TCP4-dependent induction of CONSTANS transcription requires GIGANTEA in photoperiodic flowering in Arabidopsis. PLoS Genet., 2017. 13(6): p. e1006856 [PMID:28628608] Koyama T,Sato F,Ohme-Takagi M Roles of miR319 and TCP Transcription Factors in Leaf Development. Plant Physiol., 2017. 175(2): p. 874-885 [PMID:28842549] Bresso EG,Chorostecki U,Rodriguez RE,Palatnik JF,Schommer C Spatial Control of Gene Expression by miR319-Regulated TCP Transcription Factors in Leaf Development. Plant Physiol., 2018. 176(2): p. 1694-1708 [PMID:29133375] Vadde BVL,Challa KR,Nath U The TCP4 transcription factor regulates trichome cell differentiation by directly activating GLABROUS INFLORESCENCE STEMS in Arabidopsis thaliana. Plant J., 2018. 93(2): p. 259-269 [PMID:29165850] Challa KR,Rath M,Nath U The CIN-TCP transcription factors promote commitment to differentiation in Arabidopsis leaf pavement cells via both auxin-dependent and independent pathways. PLoS Genet., 2019. 15(2): p. e1007988 [PMID:30742619]