PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pbr021365.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus
Family LSD
Protein Properties Length: 190aa    MW: 19850.1 Da    PI: 8.1746
Description LSD family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pbr021365.1genomeCPETRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-LSD139.68.6e-13731125
      zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                 C+gCr +L YPrGA++V+CalC+ +
  Pbr021365.1  7 CSGCRSVLLYPRGATNVCCALCNII 31
                 **********************976 PP

2zf-LSD143.45.7e-144670125
      zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                 CggCrtlL+ +rGA+sVRC++C+tV
  Pbr021365.1 46 CGGCRTLLMHTRGATSVRCSCCHTV 70
                 ************************9 PP

3zf-LSD1482.1e-1584108125
      zf-LSD1   1 CggCrtlLsYPrGApsVRCalCdtV 25 
                  Cg+Crt+L+YP+GApsV+Ca+C+ V
  Pbr021365.1  84 CGNCRTTLMYPYGAPSVKCAVCQYV 108
                  **********************987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
TIGRFAMsTIGR010531.7E-11432IPR005735Zinc finger, LSD1-type
PfamPF069431.1E-10730IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010538.3E-164372IPR005735Zinc finger, LSD1-type
PfamPF069436.0E-124670IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010539.9E-1381109IPR005735Zinc finger, LSD1-type
PfamPF069433.8E-1484108IPR005735Zinc finger, LSD1-type
Sequence ? help Back to Top
Protein Sequence    Length: 190 aa     Download sequence    Send to blast
MQSQLVCSGC RSVLLYPRGA TNVCCALCNI ITPVPPPGTE MAQLICGGCR TLLMHTRGAT  60
SVRCSCCHTV NLAPASSQVA HINCGNCRTT LMYPYGAPSV KCAVCQYVTN ASMANMRVPI  120
PAHRPNGTTN SGMVPSTSAS QTVVVENPMS VDESGKLLAI PRSQQAALCH GGEECCPCIM  180
AWIRTSSAN*
Functional Description ? help Back to Top
Source Description
UniProtNegative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269|PubMed:10550898, ECO:0000269|PubMed:11595797, ECO:0000269|PubMed:11844114, ECO:0000269|PubMed:12732715, ECO:0000269|PubMed:15347794, ECO:0000269|PubMed:16957775, ECO:0000269|PubMed:18055613, ECO:0000269|PubMed:18790826, ECO:0000269|PubMed:20456049, ECO:0000269|PubMed:21097903}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPbr021365.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By methyl viologen. {ECO:0000269|PubMed:20456049}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009353888.11e-110PREDICTED: protein LSD1 isoform X2
SwissprotP940774e-66LSD1_ARATH; Protein LSD1
TrEMBLM5WHS31e-102M5WHS3_PRUPE; Uncharacterized protein
STRINGXP_009353887.11e-109(Pyrus x bretschneideri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF40273361
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G20380.72e-68LSD family protein
Publications ? help Back to Top
  1. Spedaletti V, et al.
    Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana.
    Biochemistry, 2008. 47(17): p. 4936-47
    [PMID:18393445]
  2. Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S
    PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties.
    Plant Cell Rep., 2016. 35(3): p. 527-39
    [PMID:26754794]
  3. Czarnocka W, et al.
    The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator.
    Plant Cell Environ., 2017. 40(11): p. 2644-2662
    [PMID:28555890]
  4. Bernacki MJ, et al.
    LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana.
    Physiol Plant, 2019. 165(2): p. 369-382
    [PMID:30461017]