PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Pbr021365.1

Organism

Pyrus bretschneideri

Taxonomic ID

225117

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus

Family

LSD

Protein Properties

Length: 190aa MW: 19850.1 Da PI: 8.1746

Description

LSD family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pbr021365.1	genome	CPETR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-LSD1	39.6	8.6e-13	7	31	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 C+gCr +L YPrGA++V+CalC+ + Pbr021365.1 7 CSGCRSVLLYPRGATNVCCALCNII 31 **********************976 PP
2	zf-LSD1	43.4	5.7e-14	46	70	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 CggCrtlL+ +rGA+sVRC++C+tV Pbr021365.1 46 CGGCRTLLMHTRGATSVRCSCCHTV 70 ************************9 PP
3	zf-LSD1	48	2.1e-15	84	108	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 Cg+Crt+L+YP+GApsV+Ca+C+ V Pbr021365.1 84 CGNCRTTLMYPYGAPSVKCAVCQYV 108 **********************987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
TIGRFAMs	TIGR01053	1.7E-11	4	32	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	1.1E-10	7	30	IPR005735	Zinc finger, LSD1-type
TIGRFAMs	TIGR01053	8.3E-16	43	72	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	6.0E-12	46	70	IPR005735	Zinc finger, LSD1-type
TIGRFAMs	TIGR01053	9.9E-13	81	109	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	3.8E-14	84	108	IPR005735	Zinc finger, LSD1-type

Sequence ? help Back to Top
Protein Sequence Length: 190 aa Download sequence Send to blast
MQSQLVCSGC RSVLLYPRGA TNVCCALCNI ITPVPPPGTE MAQLICGGCR TLLMHTRGAT 60 SVRCSCCHTV NLAPASSQVA HINCGNCRTT LMYPYGAPSV KCAVCQYVTN ASMANMRVPI 120 PAHRPNGTTN SGMVPSTSAS QTVVVENPMS VDESGKLLAI PRSQQAALCH GGEECCPCIM 180 AWIRTSSAN*

Functional Description ? help Back to Top
Source	Description
UniProt	Negative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269\|PubMed:10550898, ECO:0000269\|PubMed:11595797, ECO:0000269\|PubMed:11844114, ECO:0000269\|PubMed:12732715, ECO:0000269\|PubMed:15347794, ECO:0000269\|PubMed:16957775, ECO:0000269\|PubMed:18055613, ECO:0000269\|PubMed:18790826, ECO:0000269\|PubMed:20456049, ECO:0000269\|PubMed:21097903}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Pbr021365.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By methyl viologen. {ECO:0000269\|PubMed:20456049}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009353888.1	1e-110	PREDICTED: protein LSD1 isoform X2
Swissprot	P94077	4e-66	LSD1_ARATH; Protein LSD1
TrEMBL	M5WHS3	1e-102	M5WHS3_PRUPE; Uncharacterized protein
STRING	XP_009353887.1	1e-109	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4027	33	61

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G20380.7	2e-68	LSD family protein

Publications ? help Back to Top
Spedaletti V, et al. Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana. Biochemistry, 2008. 47(17): p. 4936-47 [PMID:18393445] Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties. Plant Cell Rep., 2016. 35(3): p. 527-39 [PMID:26754794] Czarnocka W, et al. The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator. Plant Cell Environ., 2017. 40(11): p. 2644-2662 [PMID:28555890] Bernacki MJ, et al. LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana. Physiol Plant, 2019. 165(2): p. 369-382 [PMID:30461017]