PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MA_57676g0010

Organism

Picea abies

Taxonomic ID

3329

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Picea

Family

bHLH

Protein Properties

Length: 327aa MW: 35329 Da PI: 6.2629

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MA_57676g0010	genome	ConGenIE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	42.2	1.4e-13	153	195	7	54
HHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 7 erErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ErrRR+++N+++++Lr+++Pk K + a+iL AveY+k+L MA_57676g0010 153 MAERRRRKKLNDRLFTLRSVVPKV-----SKTDRASILGDAVEYLKEL 195 79*******************6.....4**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	1.31E-15	144	207	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	15.586	146	195	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	3.6E-11	152	195	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	5.7E-14	152	201	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	2.3E-14	153	205	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	3.35E-12	153	199	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 327 aa Download sequence Send to blast
MEMAWAGLLD ESFSSFRAIV DERGEYDFYP IMDPNGGTLE TLLDSSLMCS DGSVLSTVGG 60 SISTFHDLGC SITTTADTLE ALKGSDELGL LQRRAGIESG FHKNGGNEKP NGVVGERVAD 120 APHAANNNNN NGCANVASVG RGRKNGLPAK NLMAERRRRK KLNDRLFTLR SVVPKVSKTD 180 RASILGDAVE YLKELLQRIN GLHTEFMSGS SNSKPLAPTL LDFPRIMNQE YQASSLNPEV 240 ESARVEVNTR EGKALSIQMF SSKKPGLLLS TIRALDGLGL DVKQAVISCL NGFALDVFQA 300 EQHMARDVTA EEIKALLLHT AGYQAGL

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	154	161	ERRRRKKL

Functional Description ? help Back to Top
Source	Description
UniProt	Mediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA (PubMed:18641265). Functions as a dimer with SPCH during stomatal initiation (PubMed:18641265, PubMed:28507175). {ECO:0000269\|PubMed:18641265, ECO:0000269\|PubMed:28507175}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT122687	1e-180	BT122687.1 Picea sitchensis clone WS0454_C09 unknown mRNA.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_022741193.1	2e-72	transcription factor ICE1-like isoform X2
Swissprot	Q9LPW3	8e-69	SCRM2_ARATH; Transcription factor SCREAM2
TrEMBL	D5A934	1e-94	D5A934_PICSI; Uncharacterized protein
STRING	Bo5g016510.1	2e-71	(Brassica oleracea)
STRING	cassava4.1_005473m	6e-71	(Manihot esculenta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Representative plant	OGRP557	16	78

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G12860.1	4e-71	bHLH family protein

Publications ? help Back to Top
Tarasov VA,Khadeeva NV,Mel'nik VA,Ezhova TA,Shestakov SV The Atlg12860 gene of Arabidopsis thaliana determines cathelicidin-like antimicrobial activity. Dokl. Biol. Sci., 2009. [PMID:19760875] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Emmerstorfer A, et al. Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris. Biotechnol J, 2015. 10(4): p. 623-35 [PMID:25641738] Lee HG,Seo PJ The MYB96-HHP module integrates cold and abscisic acid signaling to activate the CBF-COR pathway in Arabidopsis. Plant J., 2015. 82(6): p. 962-77 [PMID:25912720] Raissig MT,Abrash E,Bettadapur A,Vogel JP,Bergmann DC Grasses use an alternatively wired bHLH transcription factor network to establish stomatal identity. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(29): p. 8326-31 [PMID:27382177] Fu ZW,Wang YL,Lu YT,Yuan TT Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis. Plant Sci., 2016. 252: p. 282-289 [PMID:27717464] de Marcos A, et al. A Mutation in the bHLH Domain of the SPCH Transcription Factor Uncovers a BR-Dependent Mechanism for Stomatal Development. Plant Physiol., 2017. 174(2): p. 823-842 [PMID:28507175]