PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MA_20585g0010

Organism

Picea abies

Taxonomic ID

3329

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Picea

Family

bHLH

Protein Properties

Length: 351aa MW: 37814.7 Da PI: 5.1402

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MA_20585g0010	genome	ConGenIE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	40.7	4.1e-13	154	196	7	54
HHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 7 erErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ErrRR+++N++++ Lr+++Pk K++ a+iL AveY+k+L MA_20585g0010 154 MAERRRRKKLNDRLFMLRSVVPKV-----SKMDRASILGDAVEYLKEL 196 79*******************6.....5**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	5.23E-16	145	210	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	15.377	147	196	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	4.1E-14	153	202	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	9.7E-11	153	196	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	5.45E-13	154	200	No hit	No description
Gene3D	G3DSA:4.10.280.10	2.1E-15	154	207	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd04873	5.13E-6	265	317	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 351 aa Download sequence Send to blast
MEMAWTGLLD ESFSSIRAML DGGGGDYDFY STMDANGGTL EALLGPSLMC PDASVLSNVG 60 GSIDTFHDLG CSITTSADTL EGPEGSDDMG LLQRRAGIEP GFHKNGSDEK PNGVVGEREA 120 DAANAANNNN NNGCAKAASV GRGRKNGLPA KNLMAERRRR KKLNDRLFML RSVVPKVSKM 180 DRASILGDAV EYLKELLQRI NDLHAELISS SYNSNSLAPI LPDFTCRMNQ EYQASPLNPE 240 VEPARVEVRT REGKALNIHM FCSKKPGLLL STVRALDGLG LDVKQAVISC LNGFALDVFE 300 AEKSMGKDVT GEEIKALLLH TADQNPWDSH GGICFSKGLL IYKEQAFPSS G

Sequence ? help Back to Top

Protein Sequence Length: 351 aa Download sequence Send to blast

MEMAWTGLLD ESFSSIRAML DGGGGDYDFY STMDANGGTL EALLGPSLMC PDASVLSNVG  60
GSIDTFHDLG CSITTSADTL EGPEGSDDMG LLQRRAGIEP GFHKNGSDEK PNGVVGEREA  120
DAANAANNNN NNGCAKAASV GRGRKNGLPA KNLMAERRRR KKLNDRLFML RSVVPKVSKM  180
DRASILGDAV EYLKELLQRI NDLHAELISS SYNSNSLAPI LPDFTCRMNQ EYQASPLNPE  240
VEPARVEVRT REGKALNIHM FCSKKPGLLL STVRALDGLG LDVKQAVISC LNGFALDVFE  300
AEKSMGKDVT GEEIKALLLH TADQNPWDSH GGICFSKGLL IYKEQAFPSS G

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	155	162	ERRRRKKL

Functional Description ? help Back to Top
Source	Description
UniProt	Mediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA (PubMed:18641265). Functions as a dimer with SPCH during stomatal initiation (PubMed:18641265, PubMed:28507175). {ECO:0000269\|PubMed:18641265, ECO:0000269\|PubMed:28507175}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT122687	1e-169	BT122687.1 Picea sitchensis clone WS0454_C09 unknown mRNA.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021673395.1	5e-77	transcription factor ICE1-like isoform X1
Swissprot	Q9LPW3	2e-72	SCRM2_ARATH; Transcription factor SCREAM2
STRING	ERN06217	3e-76	(Amborella trichopoda)
STRING	GSMUA_Achr6P08070_001	2e-77	(Musa acuminata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Representative plant	OGRP557	16	78

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G12860.1	1e-74	bHLH family protein

Publications ? help Back to Top
Tarasov VA,Khadeeva NV,Mel'nik VA,Ezhova TA,Shestakov SV The Atlg12860 gene of Arabidopsis thaliana determines cathelicidin-like antimicrobial activity. Dokl. Biol. Sci., 2009. [PMID:19760875] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Emmerstorfer A, et al. Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris. Biotechnol J, 2015. 10(4): p. 623-35 [PMID:25641738] Lee HG,Seo PJ The MYB96-HHP module integrates cold and abscisic acid signaling to activate the CBF-COR pathway in Arabidopsis. Plant J., 2015. 82(6): p. 962-77 [PMID:25912720] Raissig MT,Abrash E,Bettadapur A,Vogel JP,Bergmann DC Grasses use an alternatively wired bHLH transcription factor network to establish stomatal identity. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(29): p. 8326-31 [PMID:27382177] Fu ZW,Wang YL,Lu YT,Yuan TT Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis. Plant Sci., 2016. 252: p. 282-289 [PMID:27717464] de Marcos A, et al. A Mutation in the bHLH Domain of the SPCH Transcription Factor Uncovers a BR-Dependent Mechanism for Stomatal Development. Plant Physiol., 2017. 174(2): p. 823-842 [PMID:28507175]