PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MA_10428446g0010
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Picea
Family TALE
Protein Properties Length: 440aa    MW: 48674.8 Da    PI: 6.0315
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MA_10428446g0010genomeConGenIEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox291.8e-093694012355
                       SS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
          Homeobox  23 rypsaeereeLAkklgLterqVkvWFqNrRake 55 
                       +yps++++  LA+++gL+++q+ +WF N+R ++
  MA_10428446g0010 369 PYPSESQKIALAESTGLDQKQINNWFINQRKRH 401
                       8*****************************885 PP

2ELK40.46e-14321342122
               ELK   1 ELKhqLlrKYsgyLgsLkqEFs 22 
                       ELK+qLlrKYsgyL+sLkqEF+
  MA_10428446g0010 321 ELKDQLLRKYSGYLSSLKQEFL 342
                       9********************8 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM012552.1E-18177221IPR005540KNOX1
PfamPF037901.7E-21178220IPR005540KNOX1
SMARTSM012563.4E-24226277IPR005541KNOX2
PfamPF037914.4E-23229276IPR005541KNOX2
PROSITE profilePS5121311.592321341IPR005539ELK domain
PfamPF037897.2E-11321342IPR005539ELK domain
SMARTSM011887.1E-8321342IPR005539ELK domain
PROSITE profilePS5007112.6341404IPR001356Homeobox domain
SMARTSM003894.4E-13343408IPR001356Homeobox domain
SuperFamilySSF466896.84E-19343417IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.605.4E-27346406IPR009057Homeodomain-like
CDDcd000862.55E-12353405No hitNo description
PfamPF059201.7E-16361400IPR008422Homeobox KN domain
PROSITE patternPS000270379402IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0001708Biological Processcell fate specification
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010051Biological Processxylem and phloem pattern formation
GO:0010089Biological Processxylem development
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 440 aa     Download sequence    Send to blast
MMALMTEHQP ESESIMTSIP IPSSYSSYSH GHGHGHGHGH GHGQSECLLS AAAMFQSSRP  60
CQGANKFEPA NAHIGGGGAG HFVMEQFIPE QAVISDSSIS SVKTEVCSGS GGTGVPGQFE  120
LIRRKEEGRC ARAYAEPSFV VTPLVTSLPP QQQEARMVTS LAVDMDSSCS CKPIEADAMK  180
AKIIAHVHYP RLVAAYIDCQ KVGAPPDVVS ELDELSQKCH AQQCVATISI GADPELDQFM  240
EAYCEMFIKY QEELTKPFKE AMAFLKKIEN QLGALTKGTI RTSSLDQGDE RGDGAASSEE  300
EDGSGGEVEF HEVDPHAEDR ELKDQLLRKY SGYLSSLKQE FLKKKKKGKL PKEARQKLLD  360
WWTRNYKWPY PSESQKIALA ESTGLDQKQI NNWFINQRKR HWKPSEEMQF VVMDSPNPHN  420
AAFFLEGHLR TDGTAFSMDC
Functional Description ? help Back to Top
Source Description
UniProtMay play a role in meristem function, and may be involved in maintaining cells in an undifferentiated, meristematic state, and its expression disappears at the same time the shoot apex undergoes the transition from vegetative to reproductive development (PubMed:11934861). Positive regulator of LATERAL ORGAN BOUNDARIES (LOB) (PubMed:11934861). Probably binds to the DNA sequence 5'-TGAC-3' (PubMed:11934861). Able to traffic from the L1 to the L2/L3 layers of the meristem, presumably through plasmodesmata (PubMed:12900451). {ECO:0000269|PubMed:11934861, ECO:0000269|PubMed:12900451, ECO:0000269|PubMed:7866029}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00675ChIP-seqTransfer from GRMZM2G017087Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Negatively regulated by ASYMMETRIC LEAVES1 (AS1) and ASYMMETRIC LEAVES2 (AS2).
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF4832770.0AF483277.1 Picea abies KNOTTED1-like homeodomain protein 2 (HBK2) mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_022870905.11e-108homeotic protein knotted-1 isoform X1
SwissprotP466391e-108KNAT1_ARATH; Homeobox protein knotted-1-like 1
TrEMBLQ8GZN00.0Q8GZN0_PICAB; KNOTTED1-like homeodomain protein 2 (Fragment)
STRINGCagra.7524s0001.1.p1e-107(Capsella grandiflora)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP16717148
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G08150.11e-98KNOTTED-like from Arabidopsis thaliana
Publications ? help Back to Top
  1. dela Paz JS, et al.
    Chromosome fragile sites in Arabidopsis harbor matrix attachment regions that may be associated with ancestral chromosome rearrangement events.
    PLoS Genet., 2012. 8(12): p. e1003136
    [PMID:23284301]
  2. Liu C, et al.
    Phosphatidylserine synthase 1 is required for inflorescence meristem and organ development in Arabidopsis.
    J Integr Plant Biol, 2013. 55(8): p. 682-95
    [PMID:23931744]
  3. Liu B, et al.
    NEVERSHED and INFLORESCENCE DEFICIENT IN ABSCISSION are differentially required for cell expansion and cell separation during floral organ abscission in Arabidopsis thaliana.
    J. Exp. Bot., 2013. 64(17): p. 5345-57
    [PMID:23963677]
  4. Simonini S,Kater MM
    Class I BASIC PENTACYSTEINE factors regulate HOMEOBOX genes involved in meristem size maintenance.
    J. Exp. Bot., 2014. 65(6): p. 1455-65
    [PMID:24482368]
  5. Scofield S,Dewitte W,Murray JA
    STM sustains stem cell function in the Arabidopsis shoot apical meristem and controls KNOX gene expression independently of the transcriptional repressor AS1.
    Plant Signal Behav, 2018.
    [PMID:24776954]
  6. Lee JE,Lampugnani ER,Bacic A,Golz JF
    SEUSS and SEUSS-LIKE 2 coordinate auxin distribution and KNOXI activity during embryogenesis.
    Plant J., 2014. 80(1): p. 122-35
    [PMID:25060324]
  7. Rast-Somssich MI, et al.
    Alternate wiring of a KNOXI genetic network underlies differences in leaf development of A. thaliana and C. hirsuta.
    Genes Dev., 2015. 29(22): p. 2391-404
    [PMID:26588991]
  8. Duplat-Bermúdez L,Ruiz-Medrano R,Landsman D,Mariño-Ramírez L,Xoconostle-Cázares B
    Transcriptomic analysis of Arabidopsis overexpressing flowering locus T driven by a meristem-specific promoter that induces early flowering.
    Gene, 2016. 587(2): p. 120-31
    [PMID:27154816]
  9. Li Z, et al.
    Transcription factors AS1 and AS2 interact with LHP1 to repress KNOX genes in Arabidopsis.
    J Integr Plant Biol, 2016. 58(12): p. 959-970
    [PMID:27273574]
  10. Lozano-Sotomayor P, et al.
    Altered expression of the bZIP transcription factor DRINK ME affects growth and reproductive development in Arabidopsis thaliana.
    Plant J., 2016. 88(3): p. 437-451
    [PMID:27402171]
  11. Frangedakis E,Saint-Marcoux D,Moody LA,Rabbinowitsch E,Langdale JA
    Nonreciprocal complementation of KNOX gene function in land plants.
    New Phytol., 2017. 216(2): p. 591-604
    [PMID:27886385]
  12. Woerlen N, et al.
    Repression of BLADE-ON-PETIOLE genes by KNOX homeodomain protein BREVIPEDICELLUS is essential for differentiation of secondary xylem in Arabidopsis root.
    Planta, 2017. 245(6): p. 1079-1090
    [PMID:28204875]
  13. Douglas SJ,Li B,Kliebenstein DJ,Nambara E,Riggs CD
    A novel Filamentous Flower mutant suppresses brevipedicellus developmental defects and modulates glucosinolate and auxin levels.
    PLoS ONE, 2017. 12(5): p. e0177045
    [PMID:28493925]
  14. Wang X, et al.
    Overexpressed BRH1, a RING finger gene, alters rosette leaf shape in Arabidopsis thaliana.
    Sci China Life Sci, 2018. 61(1): p. 79-87
    [PMID:28887625]
  15. Simonini S,Stephenson P,Østergaard L
    A molecular framework controlling style morphology in Brassicaceae.
    Development, 2018.
    [PMID:29440299]
  16. Felipo-Benavent A, et al.
    Regulation of xylem fiber differentiation by gibberellins through DELLA-KNAT1 interaction.
    Development, 2019.
    [PMID:30389856]