PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Oropetium_20150105_15961A
Organism
Oropetium thomaeum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Cynodonteae; Tripogoninae; Oropetium
Family E2F/DP
Protein Properties Length: 426aa    MW: 47088.8 Da    PI: 7.6334
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Oropetium_20150105_15961AgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP71.41.1e-2258123171
                    E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                                rk+ksL+ll+++f++l+ +++ ++v l+++ak+L    v  +rRRiYDi+NVLe+++++ +++kn++ w g
  Oropetium_20150105_15961A  58 RKQKSLGLLCSNFVALYDREDVEAVGLDDAAKRL---GV--ERRRIYDIVNVLESVGILVRRAKNRYAWLG 123
                                79****************9999************...**..****************************87 PP
2E2F_TDP79.43.3e-25203283171
                    E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                                rkeksL+lltq+f+kl+ + e ++++l+e+a+ L+ e     ++++k+RR+YDi+NVL++lnliek     ++k+++rw g
  Oropetium_20150105_15961A 203 RKEKSLGLLTQNFVKLFLTMEVETISLDEAARLLLGEghaesNMRTKVRRLYDIANVLSSLNLIEKthqtdTRKPAFRWLG 283
                                79*******************************************************************999*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.6E-2554124IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467858.17E-1657122IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013724.2E-2758123IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.8E-2059123IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.108.3E-24200284IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.8E-33203283IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.6E-20204283IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.63E-12205283IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 426 aa     Download sequence    Send to blast
MDVAAAAVAA GPSSSSGAQA PAQSPPPPPP PPMAPQATAE AAAGFGLAKS CRHHAYSRKQ  60
KSLGLLCSNF VALYDREDVE AVGLDDAAKR LGVERRRIYD IVNVLESVGI LVRRAKNRYA  120
WLGFGGVPTA LKELKERALK EASGSAASLS LEESSTANVS DDEDDDKLGD ADEDDECEKL  180
SQSVDNLSDK PDAPPCRLRS DHRKEKSLGL LTQNFVKLFL TMEVETISLD EAARLLLGEG  240
HAESNMRTKV RRLYDIANVL SSLNLIEKTH QTDTRKPAFR WLGQAKRKQE NTTNVGLSLD  300
RKTMPYKRAF GTDLTNTDNK RGRMDTAIEN KGKLLQGSNI VKAFERQLGQ GSRSDFVYGP  360
FHPAGAKKQE VSDHMAREKE RKTIHDWENL AVSFRPQYQN QALNELFGHY VDAWKTWYND  420
FTREA*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A2e-39572753228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapOropetium_20150105_15961A
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002436789.10.0E2F transcription factor-like E2FE isoform X2
SwissprotQ8LSZ41e-108E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLC5Z7K60.0C5Z7K6_SORBI; Uncharacterized protein
STRINGSb10g008800.10.0(Sorghum bicolor)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP31853884
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-106DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]