PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Ote100275380041 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Ocimeae; Ocimum
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Family | E2F/DP | ||||||||
Protein Properties | Length: 464aa MW: 51695.4 Da PI: 6.001 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 83.1 | 2.3e-26 | 156 | 221 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL llt+kf++l++++e+g+++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg Ote100275380041|100275380041 156 RYDSSLSLLTKKFIALIKHAEDGELDLNKAADTL---QV--QKRRIYDITNVLEGIGLIEKKLKNRIHWKG 221 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 4.3E-28 | 153 | 223 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 8.5E-17 | 156 | 219 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.0E-33 | 156 | 221 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 2.9E-24 | 158 | 221 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF144074 | 2.07E-18 | 236 | 323 | No hit | No description |
CDD | cd14660 | 4.94E-26 | 237 | 323 | No hit | No description |
Pfam | PF16421 | 1.3E-13 | 237 | 321 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 464 aa Download sequence Send to blast |
MAARGTPSRD AAATPSAAAS NGQILHQQQT PPPAIRRHLP FASMKPPFVS PGDYHRFSTX 60 XXXXXXXXXH LSEAIVIKSP PFKRKNGYQN NEVESSEWTA SPVYSDIANS PFRTPVSAKG 120 RATSRSKATK NNRSVPSTPI SNVDAPSPLT PASSCRYDSS LSLLTKKFIA LIKHAEDGEL 180 DLNKAADTLQ VQKRRIYDIT NVLEGIGLIE KKLKNRIHWK GLDPSRPGEV DKDGTLLHAE 240 IENLSMEERS LDERIRQMQE KLRNLSEDEN NQRWLFVTED DIKNLPCFQL SKHPMGPPSK 300 FQILMRIILR STMGPIDVYL VSQFEEKFEE MNGVDNSTNF PVASSSGSHE NLAVDRSPLA 360 HEPPQFETHT REIHGLDSGY GSSQEYPGGM TRIIPSNIDN DADYWLLSDA DISITDMWKT 420 DTGVEWNDVN MLHDELEMAG ISTPRAHIPA SGVADVHPVD NVQP |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 5e-24 | 151 | 224 | 2 | 76 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_011094221.1 | 0.0 | transcription factor E2FA | ||||
Swissprot | Q9FNY0 | 1e-119 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | A0A4D9AXF6 | 0.0 | A0A4D9AXF6_SALSN; Uncharacterized protein | ||||
STRING | Migut.J00719.1.p | 0.0 | (Erythranthe guttata) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Asterids | OGEA1077 | 24 | 84 |
Publications ? help Back to Top | |||
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