PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Ote100265120171

Organism

Ocimum tenuiflorum

Taxonomic ID

204149

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Ocimeae; Ocimum

Family

HD-ZIP

Protein Properties

Length: 677aa MW: 74444.6 Da PI: 6.2673

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Ote100265120171	genome	OteDB	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	46.5	6.5e-15	1	39	18	56
HHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 18 lFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 +F+++++p++++r +L+++l+L rq+k+WFqNrR+++k Ote100265120171\|100265120171 1 MFKECPHPDEKARNQLSRELNLHPRQIKFWFQNRRTQMK 39 69**********************************998 PP
2	START	174.3	7.8e-55	183	408	2	206
HHHHHHHHHHHHHHHC-TT-EEEE.......EXCCTTEEEEEEESSS.....SCEEEEEEEECCSCHHHHHHHHHCCCGGC CS START 2 laeeaaqelvkkalaeepgWvkss.......esengdevlqkfeeskv....dsgealrasgvvdmvlallveellddkeq 71 +a a++el+++++ +ep+W k en++ v q++ + ++ea+r+sgvv+m++ lv ++d k + Ote100265120171\|100265120171 183 IAANAMDELIRLMQGNEPLWIKGGdgrgetlNLENYERVFQSPYSH-MknpsIRIEASRDSGVVIMNCLALVDMFMDAK-K 261 67889***************998888777778888888888553.368999***********************. PP T-TT-S....EEEEEEEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TT CS START 72 Wdetla....kaetlevissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesss 141 W e ++ +a+t++vissg g+lqlm+ elq+ls lvp R +f+R+++q ++g w+ivdvS d++ + ++ ss Ote100265120171\|100265120171 262 WVELFPtivsRAKTIDVISSGmmgsqsGTLQLMYEELQVLSALVPtRQLYFLRFCQQIEQGLWAIVDVSYDVPHQDSQFSS 342 ***99999*************************************************************999999 PP SEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS START 142 vvRaellpSgiliepksnghskvtwvehvdlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206 + +a++lpSg+ +++++ng+skvtwveh++++++ p h l+r l++sgla+ga +w++tlqr ce+ Ote100265120171\|100265120171 343 SCKAQRLPSGCFVQEMPNGYSKVTWVEHWEVEDKAPiHRLYRDLIHSGLAFGAERWLSTLQRVCER 408 9*************************************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00389	3.2E-4	1	45	IPR001356	Homeobox domain
SuperFamily	SSF46689	1.63E-12	1	44	IPR009057	Homeodomain-like
PROSITE profile	PS50071	14.592	1	41	IPR001356	Homeobox domain
Pfam	PF00046	2.3E-12	1	39	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	1.5E-14	1	45	IPR009057	Homeodomain-like
CDD	cd00086	5.69E-13	2	42	No hit	No description
PROSITE pattern	PS00027	0	16	39	IPR017970	Homeobox, conserved site
PROSITE profile	PS50848	48.372	173	411	IPR002913	START domain
SuperFamily	SSF55961	1.28E-34	174	409	No hit	No description
CDD	cd08875	1.52E-116	177	407	No hit	No description
SMART	SM00234	1.1E-43	182	408	IPR002913	START domain
Pfam	PF01852	1.7E-46	183	408	IPR002913	START domain
SuperFamily	SSF55961	2.47E-22	429	667	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009828	Biological Process	plant-type cell wall loosening
GO:0010091	Biological Process	trichome branching
GO:0005634	Cellular Component	nucleus
GO:0000976	Molecular Function	transcription regulatory region sequence-specific DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0008289	Molecular Function	lipid binding

Sequence ? help Back to Top
Protein Sequence Length: 677 aa Download sequence Send to blast
MFKECPHPDE KARNQLSREL NLHPRQIKFW FQNRRTQMKA QHERADNCSL RAENDKIRCE 60 NIAIREALKN VICPSCGSSP ASEDSYFDEQ KLRIENSHLK EELDRVSSIA AKYIGRPISQ 120 LPPVQPIHLS SLDLSMASFG GHGIQGPSLD LDLLHGSSSS VIPNLPFPQL SISDMDKSLM 180 ADIAANAMDE LIRLMQGNEP LWIKGGDGRG ETLNLENYER VFQSPYSHMK NPSIRIEASR 240 DSGVVIMNCL ALVDMFMDAK KWVELFPTIV SRAKTIDVIS SGMMGSQSGT LQLMYEELQV 300 LSALVPTRQL YFLRFCQQIE QGLWAIVDVS YDVPHQDSQF SSSCKAQRLP SGCFVQEMPN 360 GYSKVTWVEH WEVEDKAPIH RLYRDLIHSG LAFGAERWLS TLQRVCERFA CLMVSGHSTR 420 DLGGVIPSPE GKRSMMKLAQ RMVNNFCSSI NPANGQQWTT LSGLNEFEVR ATLHKSTDPG 480 QPSGVVLSAA ATIWMPVPPA SVFNFFRDER TRPQWDVLSN QNPVQEVAHI ANGSHPGNCI 540 SVLRAFNTSQ NNMLILQESC VDSSGSLVVY CPVDLPAINM AMSGEDPSYF PLLPSGFTIS 600 PDGGYGGGVD GASTSSSTGG GGSAATSSGS LITVVFQILV SNLPSARLSP ESVTTVNNLI 660 GNTIHQIKAA LNCTTTC

Sequence ? help Back to Top

Protein Sequence Length: 677 aa Download sequence Send to blast

MFKECPHPDE KARNQLSREL NLHPRQIKFW FQNRRTQMKA QHERADNCSL RAENDKIRCE  60
NIAIREALKN VICPSCGSSP ASEDSYFDEQ KLRIENSHLK EELDRVSSIA AKYIGRPISQ  120
LPPVQPIHLS SLDLSMASFG GHGIQGPSLD LDLLHGSSSS VIPNLPFPQL SISDMDKSLM  180
ADIAANAMDE LIRLMQGNEP LWIKGGDGRG ETLNLENYER VFQSPYSHMK NPSIRIEASR  240
DSGVVIMNCL ALVDMFMDAK KWVELFPTIV SRAKTIDVIS SGMMGSQSGT LQLMYEELQV  300
LSALVPTRQL YFLRFCQQIE QGLWAIVDVS YDVPHQDSQF SSSCKAQRLP SGCFVQEMPN  360
GYSKVTWVEH WEVEDKAPIH RLYRDLIHSG LAFGAERWLS TLQRVCERFA CLMVSGHSTR  420
DLGGVIPSPE GKRSMMKLAQ RMVNNFCSSI NPANGQQWTT LSGLNEFEVR ATLHKSTDPG  480
QPSGVVLSAA ATIWMPVPPA SVFNFFRDER TRPQWDVLSN QNPVQEVAHI ANGSHPGNCI  540
SVLRAFNTSQ NNMLILQESC VDSSGSLVVY CPVDLPAINM AMSGEDPSYF PLLPSGFTIS  600
PDGGYGGGVD GASTSSSTGG GGSAATSSGS LITVVFQILV SNLPSARLSP ESVTTVNNLI  660
GNTIHQIKAA LNCTTTC

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269\|PubMed:16778018, ECO:0000269\|PubMed:18451323, ECO:0000269\|PubMed:23095885, ECO:0000269\|PubMed:24821957, ECO:0000269\|PubMed:24824485, ECO:0000269\|PubMed:25564655, ECO:0000269\|PubMed:25752924}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00232	DAP	Transfer from AT1G73360	Download

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011086973.1	0.0	homeobox-leucine zipper protein HDG11
Swissprot	Q9FX31	0.0	HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBL	A0A4D9AMS8	0.0	A0A4D9AMS8_SALSN; Homeobox-leucine zipper protein
STRING	Migut.O00242.1.p	0.0	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2490	23	51

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Khosla A, et al. HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23. Plant Cell, 2014. 26(5): p. 2184-2200 [PMID:24824485] Horstman A, et al. AIL and HDG proteins act antagonistically to control cell proliferation. Development, 2015. 142(3): p. 454-64 [PMID:25564655] Cai XT,Xu P,Wang Y,Xiang CB Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis. J Integr Plant Biol, 2015. 57(12): p. 1017-30 [PMID:25752924] Yu LH, et al. Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field. Plant Biotechnol. J., 2016. 14(1): p. 72-84 [PMID:25879154] Zhu Z, et al. Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance. Front Plant Sci, 2016. 7: p. 1285 [PMID:27625663] Liu Y, et al. Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza. Protoplasma, 2017. 254(4): p. 1617-1625 [PMID:27915455] Ueda M, et al. Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote. Genes Dev., 2017. 31(6): p. 617-627 [PMID:28404632] Lung SC, et al. Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors. New Phytol., 2018. 218(1): p. 183-200 [PMID:29288621] Zheng G, et al. Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.). Front Plant Sci, 2017. 8: p. 2125 [PMID:29326737]