PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Ote100259270021

Organism

Ocimum tenuiflorum

Taxonomic ID

204149

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Ocimeae; Ocimum

Family

C3H

Protein Properties

Length: 336aa MW: 37518.1 Da PI: 9.3459

Description

C3H family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Ote100259270021	genome	OteDB	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-CCCH	29.9	9.8e-10	267	288	6	27
-SGGGGTS--TTTTT-SS-SSS CS zf-CCCH 6 CrffartGtCkyGdrCkFaHgp 27 C +f rtG+C+yG++Ck+ H++ Ote100259270021\|100259270021 267 CTRFVRTGWCQYGESCKYYHPK 288 ********************96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00220	5.3E-19	1	161	IPR000719	Protein kinase domain
PROSITE profile	PS50011	29.559	1	161	IPR000719	Protein kinase domain
SuperFamily	SSF56112	1.9E-52	14	167	IPR011009	Protein kinase-like domain
Gene3D	G3DSA:1.10.510.10	7.1E-47	15	200	No hit	No description
Pfam	PF00069	1.3E-40	16	161	IPR000719	Protein kinase domain
PROSITE pattern	PS00108	0	30	42	IPR008271	Serine/threonine-protein kinase, active site
SuperFamily	SSF57667	6.78E-5	218	252	No hit	No description
SMART	SM00356	0.0092	263	288	IPR000571	Zinc finger, CCCH-type
SuperFamily	SSF90229	1.96E-6	265	290	IPR000571	Zinc finger, CCCH-type
Gene3D	G3DSA:4.10.1000.10	4.5E-5	266	288	IPR000571	Zinc finger, CCCH-type
Pfam	PF00642	2.1E-7	266	288	IPR000571	Zinc finger, CCCH-type
PROSITE profile	PS50103	13.15	266	289	IPR000571	Zinc finger, CCCH-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006468	Biological Process	protein phosphorylation
GO:0004672	Molecular Function	protein kinase activity
GO:0005524	Molecular Function	ATP binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 336 aa Download sequence Send to blast
MAERVVGHGS FGVVFRIFRA LSYIHCGIGV CHRDIKSQNL LVNPHTHQVK LCDFGSAKVL 60 VKGEPNISYI CSRYYRAPEL IFGATEYNTS IDIWSAGCVL AELLLGQPLF PGESGVDQLV 120 EIIKIFHKRM PPEAVDLVSR LLQYSPYLRC SALDAMAHPF FDELRDPNTR LPNGRFLPPL 180 FNFKPQGAPF RNLNKVDSRS RKKTVSRPRA MIPPGNLFAD TPSARRTHLN GVSHQRAKAL 240 WYDAFLRSSQ FGLDEVEGLQ SIGNGVCTRF VRTGWCQYGE SCKYYHPKTN LSNTNAKNME 300 AVVFRNQMGA SPGNLPPSLL PPPEGGYPPL PSIDWG

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1r0e_A	6e-80	14	186	133	336	Glycogen synthase kinase-3 beta
1r0e_B	6e-80	14	186	133	336	Glycogen synthase kinase-3 beta
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Functional Description ? help Back to Top
Source	Description
UniProt	May mediate extracellular signals to regulate transcription in differentiating cells. Probably involved first at the cortical polarity site, to restrict MAPK signaling and promote asymmetric cell division (ACD), and second in the nucleus of stomatal lineage ground cells (SLGCs) or meristemoids, to limit cell division and to promote differentiation into pavement or stomatal guard cells, respectively (PubMed:30429609). Phosphorylate YDA and SPCH in vitro (PubMed:30429609). {ECO:0000269\|PubMed:30429609}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_022865017.1	1e-111	shaggy-related protein kinase NtK-1-like isoform X3
Refseq	XP_022865025.1	1e-111	shaggy-related protein kinase NtK-1-like isoform X3
Swissprot	P43289	1e-106	KSG3_ARATH; Shaggy-related protein kinase gamma
TrEMBL	A0A4D9ABT1	1e-151	A0A4D9ABT1_SALSN; Uncharacterized protein
STRING	LPERR01G09130.1	1e-126	(Leersia perrieri)

Publications ? help Back to Top
Dornelas MC,Wittich P,von Recklinghausen I,van Lammeren A,Kreis M Characterization of three novel members of the Arabidopsis SHAGGY-related protein kinase (ASK) multigene family. Plant Mol. Biol., 1999. 39(1): p. 137-47 [PMID:10080716] Dornelas MC,Van Lammeren AA,Kreis M Arabidopsis thaliana SHAGGY-related protein kinases (AtSK11 and 12) function in perianth and gynoecium development. Plant J., 2000. 21(5): p. 419-29 [PMID:10758494] Jonak C,Hirt H Glycogen synthase kinase 3/SHAGGY-like kinases in plants: an emerging family with novel functions. Trends Plant Sci., 2002. 7(10): p. 457-61 [PMID:12399181] Takahashi N, et al. Expression and interaction analysis of Arabidopsis Skp1-related genes. Plant Cell Physiol., 2004. 45(1): p. 83-91 [PMID:14749489] Richard O,Paquet N,Haudecoeur E,Charrier B Organization and expression of the GSK3/shaggy kinase gene family in the moss Physcomitrella patens suggest early gene multiplication in land plants and an ancestral response to osmotic stress. J. Mol. Evol., 2005. 61(1): p. 99-113 [PMID:16007489] Youn JH, et al. Structural and functional characterization of Arabidopsis GSK3-like kinase AtSK12. Mol. Cells, 2013. 36(6): p. 564-70 [PMID:24292946] Zhu JY, et al. The F-box Protein KIB1 Mediates Brassinosteroid-Induced Inactivation and Degradation of GSK3-like Kinases in Arabidopsis. Mol. Cell, 2017. 66(5): p. 648-657.e4 [PMID:28575660] Mittal S, et al. Comparative Analysis of CDPK Family in Maize, Arabidopsis, Rice, and Sorghum Revealed Potential Targets for Drought Tolerance Improvement. Front Chem, 2017. 5: p. 115 [PMID:29312925] Houbaert A, et al. POLAR-guided signalling complex assembly and localization drive asymmetric cell division. Nature, 2018. 563(7732): p. 574-578 [PMID:30429609] Bianchi MW,Guivarc'h D,Thomas M,Woodgett JR,Kreis M Arabidopsis homologs of the shaggy and GSK-3 protein kinases: molecular cloning and functional expression in Escherichia coli. Mol. Gen. Genet., 1994. 242(3): p. 337-45 [PMID:7509023] Dornelas MC,Lejeune B,Dron M,Kreis M The Arabidopsis SHAGGY-related protein kinase (ASK) gene family: structure, organization and evolution. Gene, 1998. 212(2): p. 249-57 [PMID:9611268]