PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ote100205630101
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Ocimeae; Ocimum
Family NAC
Protein Properties Length: 279aa    MW: 32543.3 Da    PI: 9.5566
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Ote100205630101genomeOteDB-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM1064.7e-334712252128
                           NAM  52 kaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128
                                   ++e++ewyfFs++d+ky+tg+r+nrat++g+Wkatg+dk+vls k++ +g++ktLvfykgrap+g+ktdW+mheyrl
  Ote100205630101|100205630101  47 YEEQNEWYFFSHKDRKYPTGTRTNRATTAGFWKATGRDKAVLS-KEKIIGMRKTLVFYKGRAPNGRKTDWIMHEYRL 122
                                   35678**************************************.9999***************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5100536.8271143IPR003441NAC domain
SuperFamilySSF1019415.89E-3847143IPR003441NAC domain
PfamPF023651.1E-1551122IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 279 aa     Download sequence    Send to blast
MRLRLHHWGV SKETKGSRTW KWSRAFLPAF DSIQQKKNSW DRCKLGYEEQ NEWYFFSHKD  60
RKYPTGTRTN RATTAGFWKA TGRDKAVLSK EKIIGMRKTL VFYKGRAPNG RKTDWIMHEY  120
RLQTSENGPP QEEGWVVCRA FKKPNPSHKQ GFEAWSYMRN MNYRPPSYPN TSNLLQIFDP  180
NHNQATNHQQ PPFPKLDSPT SFATNETSFC NDNEAHEDIK SSFGNNFSEW KSFEKLLGSS  240
HQLVGSSSYG YTSMPLVPQN DEMEDQSHLS HVLECFPDL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ut4_A4e-315014970171NO APICAL MERISTEM PROTEIN
1ut4_B4e-315014970171NO APICAL MERISTEM PROTEIN
1ut7_A4e-315014970171NO APICAL MERISTEM PROTEIN
1ut7_B4e-315014970171NO APICAL MERISTEM PROTEIN
3swm_A4e-315014973174NAC domain-containing protein 19
3swm_B4e-315014973174NAC domain-containing protein 19
3swm_C4e-315014973174NAC domain-containing protein 19
3swm_D4e-315014973174NAC domain-containing protein 19
3swp_A4e-315014973174NAC domain-containing protein 19
3swp_B4e-315014973174NAC domain-containing protein 19
3swp_C4e-315014973174NAC domain-containing protein 19
3swp_D4e-315014973174NAC domain-containing protein 19
4dul_A4e-315014970171NAC domain-containing protein 19
4dul_B4e-315014970171NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (e.g. genes involved in secondary wall biosynthesis, cell wall modification such as xylan accumulation, and programmed cell death) (PubMed:20935069, PubMed:20488898, PubMed:22037706, PubMed:21284754). Involved in xylem formation in roots and shoots, especially regulating protoxylem vessel differentiation by promoting immature xylem vessel-specific genes expression (PubMed:16103214, PubMed:18445131, PubMed:20488898, PubMed:21498679, PubMed:21284754). Can activate the expression of several genes including XCP1, MYB46, NAC010/SND3, MYB103, MYB58, MYB63, MYB83, KNAT7, ASL19 and ASL20 (PubMed:17890373, PubMed:19088331, PubMed:18952777, PubMed:19122102, PubMed:19808805, PubMed:20935069, PubMed:21284754). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:17890373, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:18952777, ECO:0000269|PubMed:19088331, ECO:0000269|PubMed:19122102, ECO:0000269|PubMed:19808805, ECO:0000269|PubMed:20488898, ECO:0000269|PubMed:20935069, ECO:0000269|PubMed:21284754, ECO:0000269|PubMed:21498679, ECO:0000269|PubMed:22037706}.; FUNCTION: Required for the soilborne fungal pathogen Verticillium longisporum-induced transdifferentiation of chloroplast-containing bundle sheath cells to functional xylem elements leading to stunted growth, vein clearing, and leaf chloroses, as well as xylem hyperplasia within the vasculature of leaves, hypocotyls, and roots due to reinitiation of cambial activity and transdifferentiation of xylem parenchyma cells. This developmental reprogramming mediates also an increased drought stress tolerance. {ECO:0000269|PubMed:23023171}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By brassinosteroids (e.g. brassinolide BL), auxin (e.g. 2,4-dichlorphenoxyacetic acid 2,4-D) and cytokinin (e.g. kinetin), with a synergistic effect (PubMed:16103214, PubMed:22345435). Up-regulated in a feed-back loop by ASL20 (PubMed:19088331). Levels are monitored by proteasome-mediated degradation (PubMed:18445131). Repressed by WEE1 upon replication stress to prevent premature tracheary element differentiation (PubMed:21498679). Accumulates during infection by the soilborne fungal pathogen Verticillium longisporum, especially in tissues undergoing de novo xylem formation (PubMed:23023171). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:19088331, ECO:0000269|PubMed:21498679, ECO:0000269|PubMed:22345435, ECO:0000269|PubMed:23023171}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011099157.11e-109NAC domain-containing protein 30
RefseqXP_020547703.11e-109NAC domain-containing protein 30
RefseqXP_020547704.11e-109NAC domain-containing protein 30
SwissprotQ9C8W92e-72NAC30_ARATH; NAC domain-containing protein 30
TrEMBLA0A2G9GB681e-104A0A2G9GB68_9LAMI; Uncharacterized protein
STRINGEOY172091e-93(Theobroma cacao)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA13424297
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Kakehi J, et al.
    Mutations in ribosomal proteins, RPL4 and RACK1, suppress the phenotype of a thermospermine-deficient mutant of Arabidopsis thaliana.
    PLoS ONE, 2015. 10(1): p. e0117309
    [PMID:25625317]
  3. Li Z, et al.
    A Transcriptional and Metabolic Framework for Secondary Wall Formation in Arabidopsis.
    Plant Physiol., 2016. 172(2): p. 1334-1351
    [PMID:27566165]
  4. de Lucas M, et al.
    Transcriptional Regulation of Arabidopsis Polycomb Repressive Complex 2 Coordinates Cell-Type Proliferation and Differentiation.
    Plant Cell, 2016. 28(10): p. 2616-2631
    [PMID:27650334]
  5. Tan TT, et al.
    Transcription Factors VND1-VND3 Contribute to Cotyledon Xylem Vessel Formation.
    Plant Physiol., 2018. 176(1): p. 773-789
    [PMID:29133368]
  6. Ohashi-Ito K,Iwamoto K,Fukuda H
    LOB DOMAIN-CONTAINING PROTEIN 15 Positively Regulates Expression of VND7, a Master Regulator of Tracheary Elements.
    Plant Cell Physiol., 2018. 59(5): p. 989-996
    [PMID:29444288]