PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ote100152750061
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Ocimeae; Ocimum
Family bHLH
Protein Properties Length: 555aa    MW: 62301.9 Da    PI: 7.2635
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Ote100152750061genomeOteDB-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH39.78.9e-13387433455
                                   HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
                           HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                                   +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI +Lq
  Ote100152750061|100152750061 387 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYITELQ 433
                                   799***********************66......*****************99 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142154.0E-2446179IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.85383432IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.87E-13386437No hitNo description
SuperFamilySSF474592.62E-18386445IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.104.4E-18387444IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000103.1E-10387433IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.3E-16389438IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 555 aa     Download sequence    Send to blast
MGVVGWSNDD KAMAAAVLGT KAFDYLMSSS VSAECSLMAM GNDENLQNKL ADLVERPNSS  60
NFCWNYAIFW QLSREAREDE ESEVTRILKM RLEDESQQTM RKRVLQRLHT LFGGGDEDNY  120
AFGLDKVTDT EMFFLASMYF SFPRGEGGPG KCFGSSKHVW ISDALKSSAD YCVRLSQMHP  180
GKHGTIEGGW IFIFVXXXXX XXXXXXXRSK QTAAVATVTD KKDTNGPIPN LAIGSRPEAI  240
PKIFGQDLNS SHVQYRENVP VRKAEVHDNR NWDARNRLPF TNNRNGFHAA TWTQYSPQTP  300
AKTRAELADR NREEFVLNNF QHQKPAQMQI DFTGATSRPL NSHQQSLESE LSDVEASCKE  360
EVAGLSEDKR PRKRGRKPAN GRDEPLNHVE AERQRREKLN QRFYALRAVV PNISKMDKAS  420
LLGDAIAYIT ELQKKLKDME SERERPGSIS REASGSEAIS TRDMHDLPSS INIESGQEEI  480
TVRVSCALDA HPASKVIQAI NDAQATIIDA KMATGSERVF HTFVVKSHGS ERLTKEKLME  540
ALSHKPNSPH QLTLG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A6e-29381443264Transcription factor MYC2
5gnj_B6e-29381443264Transcription factor MYC2
5gnj_E6e-29381443264Transcription factor MYC2
5gnj_F6e-29381443264Transcription factor MYC2
5gnj_G6e-29381443264Transcription factor MYC2
5gnj_I6e-29381443264Transcription factor MYC2
5gnj_M6e-29381443264Transcription factor MYC2
5gnj_N6e-29381443264Transcription factor MYC2
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011093944.10.0transcription factor bHLH13-like
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A4D8ZLA80.0A0A4D8ZLA8_SALSN; Transcription factor MYC2
STRINGXP_009781532.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA35852348
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]