PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Ote100057840101

Organism

Ocimum tenuiflorum

Taxonomic ID

204149

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Ocimeae; Ocimum

Family

C2H2

Protein Properties

Length: 178aa MW: 20309.7 Da PI: 5.0599

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Ote100057840101	genome	OteDB	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	14.6	9.8e-05	34	59	1	23
EEET..TTTEEESSHHHHHHHHHH.T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt.H 23 y Cp C k + + + L+ H+r+ H Ote100057840101\|100057840101 34 YACPyeGCEKAYIHEYKLNLHLRReH 59 89**********************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	9.3E-10	28	57	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	4.2E-6	29	57	No hit	No description
SMART	SM00355	0.0097	34	59	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.762	34	64	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	36	59	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 178 aa Download sequence Send to blast
MEPTATAKYV APPEKPVKTP KSTTTGGPSS ERPYACPYEG CEKAYIHEYK LNLHLRREHP 60 GHFPDENAKA NNENDGDEGS DQDAYVGKRG GSNGRVHKQS RPKPNLKLPP SKVAHRKTST 120 VXXXXXXXXX KKHRPLKEEI YQEEDSEETE EERDNIGDGW RRYGETNDDD DEETEYED

Functional Description ? help Back to Top
Source	Description
UniProt	Dual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269\|PubMed:22508367, ECO:0000269\|PubMed:24451981, ECO:0000269\|PubMed:26961720}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269\|PubMed:26961720}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011092328.1	8e-56	uncharacterized zinc finger protein At4g06634
Swissprot	Q2V3L3	3e-35	YY1_ARATH; Zinc finger transcription factor YY1
TrEMBL	A0A4D9AVJ8	4e-59	A0A4D9AVJ8_SALSN; Transcription factor YY
STRING	XP_009768399.1	1e-45	(Nicotiana sylvestris)
STRING	Migut.B00804.1.p	1e-45	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA7343	23	32

Publications ? help Back to Top
Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4. DNA Res., 2001. 8(6): p. 285-90 [PMID:11853315] Li T,Wu XY,Li H,Song JH,Liu JY A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network. Mol Plant, 2016. 9(5): p. 650-661 [PMID:26961720] Wu XY,Li T A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response. Front Plant Sci, 2017. 8: p. 323 [PMID:28348572]