PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ote100026010011
Organism
Ocimum tenuiflorum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Ocimeae; Ocimum
Family ARF
Protein Properties Length: 775aa    MW: 86503.2 Da    PI: 6.0429
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Ote100026010011genomeOteDB-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B372.55.2e-23130231199
                                   EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT- CS
                            B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangL 74 
                                   f+k+lt sd++++g +++p++ ae+        +   +  ++l+ +d +  +W++++i+r++++r++lt+GW+ Fv+a++L
  Ote100026010011|100026010011 130 FCKTLTASDTSTHGGFSVPRRAAEKVfppldfsQT--PPAQELIARDIHDVEWKFRHIFRGQPKRHLLTTGWSVFVSAKRL 208
                                   99*****************************7444..44459*************************************** PP

                                   -TT-EEEEEE-SSSEE..EEEEE-S CS
                            B3  75 kegDfvvFkldgrsefelvvkvfrk 99 
                                    +gD+v+F   ++++ +l+++++r+
  Ote100026010011|100026010011 209 VAGDSVIFI--WNDKNQLLLGIRRA 231
                                   *********..78888899999986 PP
2Auxin_resp109.43.8e-36256340183
                    Auxin_resp   1 aahaastksvFevvYnP.rastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkW 79 
                                   aahaa t+s F+v+YnP +as+seFv++++k+++a++ ++vsvGmRf+m fete+ss rr++Gt++g+ dldpvrWpnS+W
  Ote100026010011|100026010011 256 AAHAAGTNSCFTVFYNPmWASSSEFVIPLSKYVQAVYhTRVSVGMRFRMLFETEESSIRRYMGTITGIGDLDPVRWPNSHW 336
                                   79***************7799***************9789***************************************** PP

                    Auxin_resp  80 rsLk 83 
                                   rs+k
  Ote100026010011|100026010011 337 RSIK 340
                                   *985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019361.2E-47116259IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.106.3E-40124245IPR015300DNA-binding pseudobarrel domain
CDDcd100171.58E-21129230No hitNo description
PfamPF023625.6E-21130231IPR003340B3 DNA binding domain
SMARTSM010191.0E-23130232IPR003340B3 DNA binding domain
PROSITE profilePS5086311.97130232IPR003340B3 DNA binding domain
PfamPF065071.6E-31256340IPR010525Auxin response factor
PfamPF023091.1E-9635748IPR033389AUX/IAA domain
SuperFamilySSF542774.19E-7658734No hitNo description
PROSITE profilePS5174522.854660744IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009733Biological Processresponse to auxin
GO:0009908Biological Processflower development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 775 aa     Download sequence    Send to blast
MSMKLSTSGM GQHGHEVKEE KSLNSELWHA CAGPLVSLPT AGTRVVYFPQ GHSEQVVATT  60
NKEVDAHLPN YPSLPPQLIC QLHSVTMHAD VETDEVYAQL TLQPLTLQEQ KDACLPMELG  120
IPNRQPTNYF CKTLTASDTS THGGFSVPRR AAEKVFPPLD FSQTPPAQEL IARDIHDVEW  180
KFRHIFRGQP KRHLLTTGWS VFVSAKRLVA GDSVIFIWND KNQLLLGIRR AIRPQTLMPS  240
SVLSSDSMHI GLLAAAAHAA GTNSCFTVFY NPMWASSSEF VIPLSKYVQA VYHTRVSVGM  300
RFRMLFETEE SSIRRYMGTI TGIGDLDPVR WPNSHWRSIK VGWDESTAGD RQPRVSLWEI  360
EPLTTFPMYP SLFPLRLKRP CYPGPSSSQD GSNEVINSMA WLRGEAGSQG FNPMNFQSVG  420
MIPWMQQRLN PTAMRTDLTQ QYQAMLAGGL QNFGTGELLT NQLMQFQQPL HSLQNTGSYS  480
PISQRLQGPH SSVSPHILPT QTQMLSGNMQ RPLDQHSQAE KREEEHSYQE PHFVQHDQLQ  540
QRSTFDNLSS SISNNKFSSS MHHSISPEGS GNLLSFSRIG DPILTDQSPF SGKDASIELE  600
NQSPFSDNID SSALLMPTTA SVVDTVHAAS GFQSNPVYSG CVQDSSNYLQ TRQERPTDTC  660
TFVKVYKTGC VGRSVDIAQF SSYEELRQEV GQMFGIEGLL EDPHRSGWQL VFVDRENDVL  720
LLGDDPWEAF VNNVWYIKIL SPEDVVKLGK EEGESLSTTR DDGTSKVEGV WTSIS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1482336151388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00033PBMTransfer from AT5G37020Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011097995.10.0auxin response factor 8 isoform X4
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLA0A2G9H4W80.0A0A2G9H4W8_9LAMI; Auxin response factor
STRINGSolyc02g037530.2.10.0(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA38572339
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]