PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Ote100021710041

Organism

Ocimum tenuiflorum

Taxonomic ID

204149

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Ocimeae; Ocimum

Family

AP2

Protein Properties

Length: 354aa MW: 40135.4 Da PI: 4.5158

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Ote100021710041	genome	OteDB	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	38.7	2.4e-12	39	95	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.pseng.krkrfslgkfgtaeeAakaaiaarkkleg 55 s y+GV++++++gr++A+++d ++n ++kr + ++ +e+Aa+ ++ a++k++g Ote100021710041\|100021710041 39 SVYRGVTRHRWTGRFEAHLWDkTTWNSiQNKRGRQSAYDNEEDAARTYDLAALKYWG 95 78*****************66669999999999******************98 PP
2	AP2	26.7	1.4e-08	138	170	1	36
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkf 36 s+y+GV +++ +grW+A+I ++ +k+ +lg++ Ote100021710041\|100021710041 138 SKYRGVARHHHNGRWEARIGRVCG---NKYLYLGTY 170 89**99*******99644...4*****9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	7.78E-16	39	102	No hit	No description
SuperFamily	SSF54171	2.48E-13	39	104	IPR016177	DNA-binding domain
Pfam	PF00847	3.0E-9	39	95	IPR001471	AP2/ERF domain
SMART	SM00380	8.0E-15	40	109	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	17.425	40	103	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	9.6E-11	40	103	IPR001471	AP2/ERF domain
Pfam	PF00847	1.9E-4	138	170	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	1.37E-5	138	179	IPR016177	DNA-binding domain
SMART	SM00380	5.8E-6	139	185	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	8.61	139	171	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.7E-4	139	171	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 354 aa Download sequence Send to blast
MAPSPSPSPS PNAXXXXXXX XXXXNQSDNS ATSPKSRSSV YRGVTRHRWT GRFEAHLWDK 60 TTWNSIQNKR GRQSAYDNEE DAARTYDLAA LKYWGPSTIL NFSVEAYTKD LEEMQKLTKE 120 EYLASLRRRS SGFSRGVSKY RGVARHHHNG RWEARIGRVC GNKYLYLGTY SPNAVTNFDI 180 SNYADKLRKF LPEVQDRQEE EVIVKEETNL VPLEEVQTDE AHDNQEDPKK VVETSNPMPE 240 SKDSNESEAI NIMDMTEAHE HPWDLCLDTV FNILPIPEFS MGKASEVFDY QGFDDDIDYI 300 FDEPLDENEI LQDAMPSSCQ VDADALVAQD LKVRDATTSP SSSLSSTTSA CSDI

Sequence ? help Back to Top

Protein Sequence Length: 354 aa Download sequence Send to blast

MAPSPSPSPS PNAXXXXXXX XXXXNQSDNS ATSPKSRSSV YRGVTRHRWT GRFEAHLWDK  60
TTWNSIQNKR GRQSAYDNEE DAARTYDLAA LKYWGPSTIL NFSVEAYTKD LEEMQKLTKE  120
EYLASLRRRS SGFSRGVSKY RGVARHHHNG RWEARIGRVC GNKYLYLGTY SPNAVTNFDI  180
SNYADKLRKF LPEVQDRQEE EVIVKEETNL VPLEEVQTDE AHDNQEDPKK VVETSNPMPE  240
SKDSNESEAI NIMDMTEAHE HPWDLCLDTV FNILPIPEFS MGKASEVFDY QGFDDDIDYI  300
FDEPLDENEI LQDAMPSSCQ VDADALVAQD LKVRDATTSP SSSLSSTTSA CSDI

Functional Description ? help Back to Top
Source	Description
UniProt	May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Transcriptional activator involved in the activation of a subset of sugar-responsive genes and the control of carbon flow from sucrose import to oil accumulation in developing seeds. Binds to the GCC-box pathogenesis-related promoter element. Promotes sugar uptake and seed oil accumulation by glycolysis. Required for embryo development, seed germination and, indirectly, for seedling establishment. Negative regulator of the ABA-mediated germination inhibition. {ECO:0000250, ECO:0000269\|PubMed:12084821, ECO:0000269\|PubMed:15500472, ECO:0000269\|PubMed:15753106, ECO:0000269\|PubMed:16553903, ECO:0000269\|PubMed:16632590, ECO:0000269\|PubMed:9733529}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Transiantly in leaves by sucrose, but not by abscisic acid (ABA). {ECO:0000269\|PubMed:15753106}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011078716.1	1e-151	ethylene-responsive transcription factor WRI1
Swissprot	Q6X5Y6	6e-93	WRI1_ARATH; Ethylene-responsive transcription factor WRI1
TrEMBL	A0A4D9BTP1	1e-173	A0A4D9BTP1_SALSN; AP2-like factor, ANT lineage
STRING	Migut.B01163.1.p	1e-138	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA9134	22	27

Publications ? help Back to Top
Kim HU, et al. Ectopic overexpression of castor bean LEAFY COTYLEDON2 (LEC2) in Arabidopsis triggers the expression of genes that encode regulators of seed maturation and oil body proteins in vegetative tissues. FEBS Open Bio, 2013. 4: p. 25-32 [PMID:24363987] Wu XL,Liu ZH,Hu ZH,Huang RZ BnWRI1 coordinates fatty acid biosynthesis and photosynthesis pathways during oil accumulation in rapeseed. J Integr Plant Biol, 2014. 56(6): p. 582-93 [PMID:24393360] Shigematsu H, et al. Structural characterization of the mechanosensitive channel candidate MCA2 from Arabidopsis thaliana. PLoS ONE, 2014. 9(1): p. e87724 [PMID:24475319] Kim HU, et al. Senescence-inducible LEC2 enhances triacylglycerol accumulation in leaves without negatively affecting plant growth. Plant Biotechnol. J., 2015. 13(9): p. 1346-59 [PMID:25790072] Grimberg Å,Carlsson AS,Marttila S,Bhalerao R,Hofvander P Transcriptional transitions in Nicotiana benthamiana leaves upon induction of oil synthesis by WRINKLED1 homologs from diverse species and tissues. BMC Plant Biol., 2015. 15: p. 192 [PMID:26253704] Kanai M,Mano S,Kondo M,Hayashi M,Nishimura M Extension of oil biosynthesis during the mid-phase of seed development enhances oil content in Arabidopsis seeds. Plant Biotechnol. J., 2016. 14(5): p. 1241-50 [PMID:26503031] Li Q, et al. Wrinkled1 Accelerates Flowering and Regulates Lipid Homeostasis between Oil Accumulation and Membrane Lipid Anabolism in Brassica napus. Front Plant Sci, 2015. 6: p. 1015 [PMID:26635841] Hofvander P, et al. Potato tuber expression of Arabidopsis WRINKLED1 increase triacylglycerol and membrane lipids while affecting central carbohydrate metabolism. Plant Biotechnol. J., 2016. 14(9): p. 1883-98 [PMID:26914183] Shen SL, et al. CitAP2.10 activation of the terpene synthase CsTPS1 is associated with the synthesis of (+)-valencene in 'Newhall' orange. J. Exp. Bot., 2016. 67(14): p. 4105-15 [PMID:27194737] Adhikari ND,Bates PD,Browse J WRINKLED1 Rescues Feedback Inhibition of Fatty Acid Synthesis in Hydroxylase-Expressing Seeds. Plant Physiol., 2016. 171(1): p. 179-91 [PMID:27208047] Kim MJ,Jang IC,Chua NH The Mediator Complex MED15 Subunit Mediates Activation of Downstream Lipid-Related Genes by the WRINKLED1 Transcription Factor. Plant Physiol., 2016. 171(3): p. 1951-64 [PMID:27246098] Bhattacharya S,Das N,Maiti MK Cumulative effect of heterologous AtWRI1 gene expression and endogenous BjAGPase gene silencing increases seed lipid content in Indian mustard Brassica juncea. Plant Physiol. Biochem., 2016. 107: p. 204-213 [PMID:27314514] Ma W, et al. 14-3-3 protein mediates plant seed oil biosynthesis through interaction with AtWRI1. Plant J., 2016. 88(2): p. 228-235 [PMID:27322486] Li D, et al. MYB89 Transcription Factor Represses Seed Oil Accumulation. Plant Physiol., 2017. 173(2): p. 1211-1225 [PMID:27932421] Ivarson E, et al. Effects of Overexpression of WRI1 and Hemoglobin Genes on the Seed Oil Content of Lepidium campestre. Front Plant Sci, 2016. 7: p. 2032 [PMID:28119714] An D, et al. Expression of Camelina WRINKLED1 Isoforms Rescue the Seed Phenotype of the Arabidopsis wri1 Mutant and Increase the Triacylglycerol Content in Tobacco Leaves. Front Plant Sci, 2017. 8: p. 34 [PMID:28174580] Zhai Z,Liu H,Shanklin J Phosphorylation of WRINKLED1 by KIN10 Results in Its Proteasomal Degradation, Providing a Link between Energy Homeostasis and Lipid Biosynthesis. Plant Cell, 2017. 29(4): p. 871-889 [PMID:28314829] Jin J, et al. Transcriptome and functional analysis reveals hybrid vigor for oil biosynthesis in oil palm. Sci Rep, 2017. 7(1): p. 439 [PMID:28348403] Kong Q, et al. The Arabidopsis WRINKLED1 transcription factor affects auxin homeostasis in roots. J. Exp. Bot., 2017. 68(16): p. 4627-4634 [PMID:28981783] Kang NK, et al. Increased lipid production by heterologous expression of AtWRI1 transcription factor in Nannochloropsis salina. Biotechnol Biofuels, 2017. 10: p. 231 [PMID:29046718] Pellaud S, et al. WRINKLED1 and ACYL-COA:DIACYLGLYCEROL ACYLTRANSFERASE1 regulate tocochromanol metabolism in Arabidopsis. New Phytol., 2018. 217(1): p. 245-260 [PMID:29105089] Hanano A,Almousally I,Shaban M,Murphy DJ Arabidopsis plants exposed to dioxin result in a WRINKLED seed phenotype due to 20S proteasomal degradation of WRI1. J. Exp. Bot., 2018. 69(7): p. 1781-1794 [PMID:29394403]