PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ote100004800061
Organism
Ocimum tenuiflorum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Ocimeae; Ocimum
Family MYB
Protein Properties Length: 269aa    MW: 30536.5 Da    PI: 7.2173
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Ote100004800061genomeOteDB-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding41.14e-131257146
                                  TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
               Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46
                                  +g+W  eEde l++ v ++G+++W++I ++  ++Rt+k+c++rw +
  Ote100004800061|100004800061 12 KGPWKVEEDEVLLNHVSKYGPRDWSSIRSKGLLRRTGKSCRLRWVN 57
                                  79*************************888779***********87 PP
2Myb_DNA-binding461.2e-1468107344
                                   SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHH CS
               Myb_DNA-binding   3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrw 44 
                                   ++++eE+   +d+ +q+G++ W++Ia +++ gRt++++k++w
  Ote100004800061|100004800061  68 KFSAEEERTVIDLQAQFGNK-WAKIATYLP-GRTDNDVKNFW 107
                                   79******************.*********.*********** PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129421.538763IPR017930Myb domain
SuperFamilySSF466892.13E-289107IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.603.4E-20960IPR009057Homeodomain-like
SMARTSM007171.8E-111161IPR001005SANT/Myb domain
CDDcd001672.31E-111459No hitNo description
PfamPF139211.6E-111565No hitNo description
Gene3DG3DSA:1.10.10.601.4E-1861113IPR009057Homeodomain-like
PROSITE profilePS5129417.41964115IPR017930Myb domain
SMARTSM007172.5E-1265113IPR001005SANT/Myb domain
PfamPF002499.0E-1368107IPR001005SANT/Myb domain
CDDcd001677.06E-1168107No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0048235Biological Processpollen sperm cell differentiation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 269 aa     Download sequence    Send to blast
MRRNNEMGDI KKGPWKVEED EVLLNHVSKY GPRDWSSIRS KGLLRRTGKS CRLRWVNKLR  60
PDLKTGVKFS AEEERTVIDL QAQFGNKWAK IATYLPGRTD NDVKNFWSSR QKRLARILQT  120
SASSSSSTKS SKTPKQIPPP AFPSLKVEED HKEVASFVFP SPVMYHHSAL PLNYMPPEQD  180
HHISFPQIHS DCPLMLEGQD FIGRLGVPSF LEDGFEESSR SALGTAQVPV LPSFQSSRDT  240
EEISSLIDDF PPIDLFDQIE QLPSPSEWS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h8a_C7e-28911324126MYB TRANSFORMING PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that acts as a positive regulator of male germline development by promoting both gametic cell specification and cell cycle progression (PubMed:15694308, PubMed:15618418, PubMed:19300502, PubMed:21285328). Binds to canonical MYB sites 5'-AACCGTC-3', 5'-AAACCGC-3' and 5'-AACCGT-3' in promoters to trigger the expression of male germline-specific or enriched genes (e.g. MGH3, GEX2 and GCS1), including those required for fertilization (PubMed:21285328, PubMed:19300502). Required for sperm cell specification leading to pollen maturation by activating a germline-specific regulon (PubMed:21285328, PubMed:15694308, PubMed:15618418, PubMed:19300502). Involved in pollen mitosis entry at G2-M transition via the regulation of CYCB1-1, DAZ1 and DAZ2 expression (PubMed:15618418, PubMed:19300502, PubMed:24876252). {ECO:0000269|PubMed:15618418, ECO:0000269|PubMed:15694308, ECO:0000269|PubMed:19300502, ECO:0000269|PubMed:21285328, ECO:0000269|PubMed:24876252}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by the microRNA 159 (miR159); the production of miR159 is stimulated by the anaphase promoting complex/cyclosome (APC/C) (PubMed:21441434). Activated by ARID1 in male germline cells via specific histone acetylation regulation (e.g. H3K9Ac) (PubMed:25057814). {ECO:0000269|PubMed:21441434, ECO:0000269|PubMed:25057814}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011093325.11e-102transcription factor MYB63-like
SwissprotA0A178VEK74e-67DUO1_ARATH; Transcription factor DUO1
TrEMBLA0A4D9BH861e-121A0A4D9BH86_SALSN; Uncharacterized protein
STRINGXP_009587874.13e-83(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA42072342
Publications ? help Back to Top
  1. Zheng B,He H,Zheng Y,Wu W,McCormick S
    An ARID domain-containing protein within nuclear bodies is required for sperm cell formation in Arabidopsis thaliana.
    PLoS Genet., 2014. 10(7): p. e1004421
    [PMID:25057814]
  2. Peters B, et al.
    A Conserved cis-Regulatory Module Determines Germline Fate through Activation of the Transcription Factor DUO1 Promoter.
    Plant Physiol., 2017. 173(1): p. 280-293
    [PMID:27624837]
  3. Zheng Z, et al.
    Target RNA Secondary Structure Is a Major Determinant of miR159 Efficacy.
    Plant Physiol., 2017. 174(3): p. 1764-1778
    [PMID:28515145]