PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
|
Home TFext BLAST Prediction Download Help About Links PlantRegMap |
Transcription Factor Information
Basic Information? help Back to Top | |||||||||
---|---|---|---|---|---|---|---|---|---|
TF ID | LOC_Os12g06200.2 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa
|
||||||||
Family | E2F/DP | ||||||||
Protein Properties | Length: 429aa MW: 46719.9 Da PI: 4.7213 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
|
Signature Domain? help Back to Top | |||||||
---|---|---|---|---|---|---|---|
No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 83.4 | 1.9e-26 | 130 | 195 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kfl+ll+ ++ giv+ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg LOC_Os12g06200.2 130 RYDSSLGLLTKKFLNLLKGAPGGIVDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNNIRWKG 195 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 8.0E-28 | 128 | 196 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.63E-16 | 130 | 193 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 8.6E-35 | 130 | 195 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 1.6E-23 | 132 | 195 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 1.92E-49 | 206 | 312 | No hit | No description |
SuperFamily | SSF144074 | 3.66E-33 | 207 | 312 | No hit | No description |
Pfam | PF16421 | 1.3E-33 | 211 | 310 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
---|---|---|---|---|---|---|
GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
---|
Protein Sequence Length: 429 aa Download sequence Send to blast |
MAAAGAGSSE VAARVLLQRY QPFAPPPGEY HQFGSGGAAA AGDMTEAVLI RTPLKRKHDR 60 EENEAAESND WMMSPGYTNP AGSPVPTPLS GKGSKAFAKS KAAKGQKSCP QTPLCASSPG 120 NPVTPVGGCR YDSSLGLLTK KFLNLLKGAP GGIVDLNNAA ETLEVQKRRI YDITNVLEGI 180 GLIEKKLKNN IRWKGIDDSR PGEVSDDMSI LQADIEALSL QEHSVDQQIS EMRDKLRGLT 240 EDENNQKWLY VTEDDIKSLP CFQNQTLIAI KAPHGTTLEV PDPDEVNDYP QRRYRIVLRS 300 TMGPIDVYLV SQFEEMSGME TPPRTVQPVS MDSLENPRTP LAAEPNKAAE SQPNIQDGLL 360 MPSDAPSSSQ DIGGMMKIVP SELDTDADYW LLSDAGVSIT DMWKTARILF QTVYHSCILP 420 FWLSSIIM* |
3D Structure ? help Back to Top | ||||||
---|---|---|---|---|---|---|
PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 1e-22 | 119 | 196 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Expression -- UniGene ? help Back to Top | ||||||
---|---|---|---|---|---|---|
UniGene ID | E-value | Expressed in | ||||
Os.424 | 0.0 | leaf| panicle| root| stem |
Expression -- Microarray ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Source | ID | E-value | ||||
GEO | 32969251 | 0.0 | ||||
Expression Atlas | Q2QXF7 | - |
Expression -- Description ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}. | |||||
Uniprot | TISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}. |
Functional Description ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Cis-element ? help Back to Top | |
---|---|
Source | Link |
PlantRegMap | LOC_Os12g06200.2 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Phenotype -- Mutation ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Source | ID | |||||
RiceGE | Os12g06200 |
Annotation -- Nucleotide ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Source | Hit ID | E-value | Description | |||
GenBank | AK059233 | 0.0 | AK059233.1 Oryza sativa Japonica Group cDNA clone:001-024-E10, full insert sequence. |
Annotation -- Protein ? help Back to Top | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-value | Description | ||||
Refseq | XP_015620749.1 | 0.0 | transcription factor E2FA | ||||
Swissprot | Q9FNY0 | 1e-123 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | Q2QXF7 | 0.0 | Q2QXF7_ORYSJ; Transcription factor E2F/dimerisation partner family protein, expressed | ||||
STRING | ORUFI12G04170.1 | 0.0 | (Oryza rufipogon) | ||||
STRING | OS12T0158800-01 | 0.0 | (Oryza sativa) | ||||
STRING | ONIVA12G03230.1 | 0.0 | (Oryza nivara) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Hit ID | E-value | Description | ||||
AT2G36010.1 | 1e-108 | E2F transcription factor 3 |
Link Out ? help Back to Top | |
---|---|
Phytozome | LOC_Os12g06200.2 |
Publications ? help Back to Top | |||
---|---|---|---|
|