PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID LOC_Os06g13670.1
Common NameLOC4340638, OJ1136_C11.2, Os06g0245900, OSNPB_060245900
Organism
Oryza sativa subsp. japonica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa
Family E2F/DP
Protein Properties Length: 426aa    MW: 46848.6 Da    PI: 8.9707
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
LOC_Os06g13670.1genomeMSUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP72.25.9e-2357122171
           E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                       rk+ksL+ll+++f++l+ +++ + v l+++a++L    v  +rRRiYDi+NVLe+++++ +++kn+++w+g
  LOC_Os06g13670.1  57 RKQKSLGLLCTNFVALYDREDVESVGLDDAARRL---GV--ERRRIYDIVNVLESIGMLVRRAKNRYTWIG 122
                       79****************9999************...**..****************************98 PP
2E2F_TDP80.91.1e-25203283171
           E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                       rkeksL+lltq+f+kl+ + e ++++l+e+ak+L+ e     ++++k+RR+YDi+NVL++lnliek     ++k+++rw g
  LOC_Os06g13670.1 203 RKEKSLGLLTQNFVKLFLTMEIETISLDEAAKRLLGEghaanNMRTKVRRLYDIANVLSSLNLIEKtqqadSRKPAFRWLG 283
                       79****************************************************************9999999******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.5E-2553123IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.26E-1656121IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.9E-2857122IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.1E-2058122IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.106.6E-24200284IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.9E-33203283IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023194.7E-21204283IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467855.85E-13205283IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0020048anatomymicrospore
PO:0001009developmental stageD pollen mother cell meiosis stage
PO:0007130developmental stagesporophyte reproductive stage
Sequence ? help Back to Top
Protein Sequence    Length: 426 aa     Download sequence    Send to blast
MAAAADAPPP PPEVAPPAPA PAPAPAPYQP PRLAVADGAG GGGGGGGKPC RHHAYSRKQK  60
SLGLLCTNFV ALYDREDVES VGLDDAARRL GVERRRIYDI VNVLESIGML VRRAKNRYTW  120
IGFGGVPAAL AKLKEMSLRA VSSVASPSLD ETSAANVSDD EDDDKLDDAE GDAESEKLSL  180
SQSIDNPSDK PDAPPCKLRS EHRKEKSLGL LTQNFVKLFL TMEIETISLD EAAKRLLGEG  240
HAANNMRTKV RRLYDIANVL SSLNLIEKTQ QADSRKPAFR WLGQAKRNEG VTVALPPTKT  300
LPNKRAFGTD LTNIDNKRGK LDSTMENRGK PTQDGGNLFN NLQRQLGQEN RSDFVYGPFH  360
PAVARKQEHG NRTVQEKERK SIQDWENLAS SFRPQYQNPG LNDLFGHYME AWRSWYSDLR  420
RDRAS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A6e-38562753228Transcription factor E2F8
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Os.501970.0root
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO379896550.0
Expression AtlasQ654W1-
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Not detected during early S phase. Expressed at both the G1/S and S/G2 transitions, with a peak during G2. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:18787127}.
UniprotTISSUE SPECIFICITY: Expressed exclusively in mitotically dividing cells. Highly expressed in young leaves and mature flowers. Lower expression in young stalk and in young and mature flowers. {ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366}.
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLOC_Os06g13670.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
RiceGEOs06g13670
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK1200320.0AK120032.1 Oryza sativa Japonica Group cDNA clone:002-186-D11, full insert sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015643420.10.0E2F transcription factor-like E2FE
SwissprotQ8LSZ41e-101E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A0E0PVQ80.0A0A0E0PVQ8_ORYRU; Uncharacterized protein
TrEMBLQ654W10.0Q654W1_ORYSJ; Os06g0245900 protein
STRINGORUFI06G09470.10.0(Oryza rufipogon)
STRINGOS06T0245900-010.0(Oryza sativa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP31853884
Representative plantOGRP24741634
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-104DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]