PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID LOC_Os01g66120.3
Common NameB1065E10.51, LOC4325006, NAC48, NAC6, Os01g0884300
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa
Family NAC
Protein Properties Length: 248aa    MW: 26472.2 Da    PI: 9.6984
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
LOC_Os01g66120.3genomeMSUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM96.93.1e-3057754128
               NAM  54 eekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128
                       +ekewyfFs+rd+ky++g+r+nra+ sgyWkatg dk+v s   + v +kk Lvfy g+apkgekt+W+mheyrl
  LOC_Os01g66120.3   5 GEKEWYFFSPRDRKYPNGSRPNRAAGSGYWKATGADKPVGS--PKPVAIKKALVFYAGKAPKGEKTNWIMHEYRL 77 
                       579************************************99..789***************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5100540.6081103IPR003441NAC domain
SuperFamilySSF1019412.62E-363103IPR003441NAC domain
PfamPF023652.1E-14977IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009611Biological Processresponse to wounding
GO:0009788Biological Processnegative regulation of abscisic acid-activated signaling pathway
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0020039anatomyleaf lamina
Sequence ? help Back to Top
Protein Sequence    Length: 248 aa     Download sequence    Send to blast
MALYGEKEWY FFSPRDRKYP NGSRPNRAAG SGYWKATGAD KPVGSPKPVA IKKALVFYAG  60
KAPKGEKTNW IMHEYRLADV DRSARKKNSL RLDDWVLCRI YNKKGGLEKP PAAAVAAAGM  120
VSSGGGVQRK PMVGVNAAVS SPPEQKPVVA GPAFPDLAAY YDRPSDSMPR LHADSSCSEQ  180
VLSPEFACEV QSQPKISEWE RTFATVGPIN PAASILDPAG SGGLGGLGGG GSDPLLQDIL  240
MYWGKPF*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ut4_A1e-48210966171NO APICAL MERISTEM PROTEIN
1ut4_B1e-48210966171NO APICAL MERISTEM PROTEIN
1ut7_A1e-48210966171NO APICAL MERISTEM PROTEIN
1ut7_B1e-48210966171NO APICAL MERISTEM PROTEIN
3swm_A2e-48210969174NAC domain-containing protein 19
3swm_B2e-48210969174NAC domain-containing protein 19
3swm_C2e-48210969174NAC domain-containing protein 19
3swm_D2e-48210969174NAC domain-containing protein 19
3swp_A2e-48210969174NAC domain-containing protein 19
3swp_B2e-48210969174NAC domain-containing protein 19
3swp_C2e-48210969174NAC domain-containing protein 19
3swp_D2e-48210969174NAC domain-containing protein 19
4dul_A1e-48210966171NAC domain-containing protein 19
4dul_B1e-48210966171NAC domain-containing protein 19
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Os.519264e-79callus| flower| leaf| panicle| root| stem
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1154845144e-79
Expression AtlasQ7F2L3-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:10660065}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds to the promoter of the stress response gene LEA19. Involved in tolerance to abiotic stresses (PubMed:20632034). Transcription activator involved in response to abiotic and biotic stresses. Involved in drought and salt stress responses, and defense response to the rice blast fungus (PubMed:17587305). Transcription activator involved tolerance to cold and salt stresses (PubMed:18273684). Transcription activator involved in tolerance to drought stress. Targets directly and activates genes involved in membrane modification, nicotianamine (NA) biosynthesis, glutathione relocation, accumulation of phosphoadenosine phosphosulfate and glycosylation in roots (PubMed:27892643). Controls root growth at early vegetative stage through chromatin modification and histone lysine deacytaltion by HDAC1 (PubMed:19453457). {ECO:0000269|PubMed:17587305, ECO:0000269|PubMed:18273684, ECO:0000269|PubMed:19453457, ECO:0000269|PubMed:20632034, ECO:0000269|PubMed:27892643}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00121DAPTransfer from AT1G01720Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapLOC_Os01g66120.3
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by drought stress, salt stress, cold stress and abscisic acid (ABA) (PubMed:20632034, PubMed:27892643). Induced by methyl jasmonate (PubMed:20632034, PubMed:11332734). Induced by infection with the rice blast fungus Magnaporthe oryzae (PubMed:11332734). {ECO:0000269|PubMed:11332734, ECO:0000269|PubMed:20632034, ECO:0000269|PubMed:27892643}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Phenotype -- Mutation ? help Back to Top
Source ID
RiceGEOs01g66120
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0281850.0AB028185.1 Oryza sativa mRNA for OsNAC6 protein, complete cds.
GenBankAK0683920.0AK068392.1 Oryza sativa Japonica Group cDNA clone:J013149P14, full insert sequence.
GenBankEU8469930.0EU846993.1 Oryza sativa Japonica Group clone KCS089G05 NAC6 protein mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015620920.11e-179NAC domain-containing protein 48
SwissprotQ7F2L31e-180NAC48_ORYSJ; NAC domain-containing protein 48
TrEMBLA0A0E0N5X51e-178A0A0E0N5X5_ORYRU; Uncharacterized protein
STRINGORUFI01G42940.11e-178(Oryza rufipogon)
STRINGOS01T0884300-011e-178(Oryza sativa)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01720.12e-84NAC family protein
Publications ? help Back to Top
  1. Kikuchi K, et al.
    Molecular analysis of the NAC gene family in rice.
    Mol. Gen. Genet., 2000. 262(6): p. 1047-51
    [PMID:10660065]
  2. Xiong L,Lee MW,Qi M,Yang Y
    Identification of defense-related rice genes by suppression subtractive hybridization and differential screening.
    Mol. Plant Microbe Interact., 2001. 14(5): p. 685-92
    [PMID:11332734]
  3. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  4. Ooka H, et al.
    Comprehensive analysis of NAC family genes in Oryza sativa and Arabidopsis thaliana.
    DNA Res., 2003. 10(6): p. 239-47
    [PMID:15029955]
  5. Ohnishi T, et al.
    OsNAC6, a member of the NAC gene family, is induced by various stresses in rice.
    Genes Genet. Syst., 2005. 80(2): p. 135-9
    [PMID:16172526]
  6. Hu H, et al.
    Characterization of transcription factor gene SNAC2 conferring cold and salt tolerance in rice.
    Plant Mol. Biol., 2008. 67(1-2): p. 169-81
    [PMID:18273684]
  7. Kim MJ, et al.
    Quadruple 9-mer-based protein binding microarray with DsRed fusion protein.
    BMC Mol. Biol., 2009. 10: p. 91
    [PMID:19761621]
  8. Chung PJ,Kim JK
    Epigenetic interaction of OsHDAC1 with the OsNAC6 gene promoter regulates rice root growth.
    Plant Signal Behav, 2009. 4(7): p. 675-7
    [PMID:19820307]
  9. Peng HF, et al.
    Fine mapping of a gene for non-pollen type thermosensitive genic male sterility in rice (Oryza sativa L.).
    Theor. Appl. Genet., 2010. 120(5): p. 1013-20
    [PMID:20012261]
  10. Takasaki H, et al.
    The abiotic stress-responsive NAC-type transcription factor OsNAC5 regulates stress-inducible genes and stress tolerance in rice.
    Mol. Genet. Genomics, 2010. 284(3): p. 173-83
    [PMID:20632034]
  11. Kim MJ, et al.
    Convenient determination of protein-binding DNA sequences using quadruple 9-mer-based microarray and DsRed-monomer fusion protein.
    Methods Mol. Biol., 2012. 786: p. 65-77
    [PMID:21938620]
  12. Gupta SK, et al.
    The single functional blast resistance gene Pi54 activates a complex defence mechanism in rice.
    J. Exp. Bot., 2012. 63(2): p. 757-72
    [PMID:22058403]
  13. Nakashima K, et al.
    Comparative functional analysis of six drought-responsive promoters in transgenic rice.
    Planta, 2014. 239(1): p. 47-60
    [PMID:24062085]
  14. Todaka D,Nakashima K,Shinozaki K,Yamaguchi-Shinozaki K
    Toward understanding transcriptional regulatory networks in abiotic stress responses and tolerance in rice.
    Rice (N Y), 2012. 5(1): p. 6
    [PMID:24764506]
  15. Qian B, et al.
    Enhanced drought tolerance in transgenic rice over-expressing of maize C4 phosphoenolpyruvate carboxylase gene via NO and Ca(2+).
    J. Plant Physiol., 2015. 175: p. 9-20
    [PMID:25460871]
  16. Shiriga K, et al.
    Genome-wide identification and expression pattern of drought-responsive members of the NAC family in maize.
    Meta Gene, 2014. 2: p. 407-17
    [PMID:25606426]
  17. Farooq MA,Detterbeck A,Clemens S,Dietz KJ
    Silicon-induced reversibility of cadmium toxicity in rice.
    J. Exp. Bot., 2016. 67(11): p. 3573-85
    [PMID:27122572]
  18. Lee DK, et al.
    The rice OsNAC6 transcription factor orchestrates multiple molecular mechanisms involving root structural adaptions and nicotianamine biosynthesis for drought tolerance.
    Plant Biotechnol. J., 2017. 15(6): p. 754-764
    [PMID:27892643]