PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID BGIOSGA006304-PA
Common NameOsI_07553
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa
Family E2F/DP
Protein Properties Length: 490aa    MW: 52490.5 Da    PI: 4.6794
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
BGIOSGA006304-PAgenomeRISView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.96.4e-27165230171
           E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                       r+++sL+llt+kf++ll+++++gi++ln++a++L   +v  ++RRiYDi+NVLe+++liek+ kn+irwkg
  BGIOSGA006304-PA 165 RYDSSLGLLTKKFINLLKQAPDGILDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIRWKG 230
                       6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.109.8E-29163232IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.0E-35165230IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467854.08E-18165228IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023192.6E-24167230IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146601.39E-49240346No hitNo description
SuperFamilySSF1440741.39E-34243346No hitNo description
PfamPF164212.5E-33245344IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 490 aa     Download sequence    Send to blast
MAGSGRPPAA QKKILQSLRP PLPFAASSRS PFAAPNDYHR FPSGGAAAAA ASGSGGIGAG  60
GAGGGGGDIE EGLVIRTPLT SDTGYTTVAT PQQKRKAPEE SDVAESSDCM ITSPGFTVSP  120
MLTPVSGKAV KTSKSKTKNN KAGPQTPTSN VGSPLNPPTP VGTCRYDSSL GLLTKKFINL  180
LKQAPDGILD LNNAAETLEV QKRRIYDITN VLEGIGLIEK TLKNRIRWKG LDDSGVELDN  240
GLSALQAEVE NLSLKEQALD ERISDMREKL RGLTEDENNQ RWLYVTEDDI KGLPCFQNET  300
LIAIKAPHGT TLEVPDPDEA GDYLQRRYRI VLRSTMGPID VYLVSQFDEK FEDLGGGATP  360
SGHANVPKHQ PTEVFNTTNA GVGQCSNSVA VDNNIQHSQT IPQDPSASHD FGGMTRIIPS  420
DIDTDADYWL ISEGDVSITD MWKTAPDVQW DEGLDTDVFL SEDVRTPSSH NQQPSAVGGP  480
QMQVSDMHKP
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A2e-23157231274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Os.4230.0callus| flower| leaf| panicle| stem
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO329787060.0
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}.
UniprotTISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0417250.0AB041725.1 Oryza sativa OsE2F1 mRNA for E2F homolog, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015623378.10.0transcription factor E2FB
SwissprotQ9FNY01e-130E2FA_ARATH; Transcription factor E2FA
TrEMBLB8AJ350.0B8AJ35_ORYSI; Uncharacterized protein
STRINGORGLA02G0166600.10.0(Oryza glaberrima)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP62537148
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-122E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]