PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID ORUFI02G20490.1
Organism
Oryza rufipogon
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza
Family E2F/DP
Protein Properties Length: 481aa    MW: 51686.7 Da    PI: 4.6824
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
ORUFI02G20490.1genomeOGEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.96.2e-27150215171
          E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                      r+++sL+llt+kf++ll+++++gi++ln++a++L   +v  ++RRiYDi+NVLe+++liek+ kn+irwkg
  ORUFI02G20490.1 150 RYDSSLGLLTKKFINLLKQAPDGILDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIRWKG 215
                      6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.109.6E-29148217IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467853.56E-18150213IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.0E-35150215IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.5E-24152215IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146602.00E-49225331No hitNo description
SuperFamilySSF1440741.33E-34228331No hitNo description
PfamPF164212.5E-33230329IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 481 aa     Download sequence    Send to blast
MAGSGRPPAA QKKILQSLRP PLPFAASSRS PFAAPNDYHR FPAGGAAAAA ASGSGGIGAG  60
GAGGGGDIEE GLVIRTPQKR KAPEESDVAE SSDCMITSPG FTVSPMLTPV SGKAVKTSKS  120
KTKNNKAGPQ TPTSNVGSPL NPPTPVGTCR YDSSLGLLTK KFINLLKQAP DGILDLNNAA  180
ETLEVQKRRI YDITNVLEGI GLIEKTLKNR IRWKGLDDSG VELDNGLSAL QAEVENLSLK  240
EQALDERISD MREKLRGLTE DENNQRWLYV TEDDIKGLPC FQNETLIAIK APHGTTLEVP  300
DPDEAGDYLQ RRYRIVLRST MGPIDVYLVS QFDEKFEDLG GGATPSGHAN VPKHQPTEVF  360
NTTNAGVGQC SNSVAVDNNI QHSQTIPQDP SASHDFGGMT RIIPSDIDTD ADYWLISEGD  420
VSITDMWKTA LLNMETADVQ WDESLDTDVF LSEDVRTPSS HNQQPSAVGG PQMQVSDMHK  480
P
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A1e-23142216274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK0686890.0AK068689.1 Oryza sativa Japonica Group cDNA clone:J013161I16, full insert sequence.
GenBankHQ8588300.0HQ858830.1 Oryza sativa Japonica Group isolate UT1329 E2F-DP transcription factor mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015623378.10.0transcription factor E2FB
SwissprotQ9FNY01e-129E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A0E0NG170.0A0A0E0NG17_ORYRU; Uncharacterized protein
STRINGORUFI02G20490.10.0(Oryza rufipogon)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP62537148
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-120E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]