PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID OPUNC04G10160.6
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza
Family E2F/DP
Protein Properties Length: 342aa    MW: 38652.3 Da    PI: 4.6092
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
OPUNC04G10160.6genomeOGEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP83.31.9e-262388171
          E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                     r+++sL+llt+kf++ll+++++g+++ln++ak L   dv  ++RRiYDi+NVLe+ +liekk kn+irw+g
  OPUNC04G10160.6 23 RYDNSLGLLTRKFINLLKQAQDGTLDLNDAAKIL---DV--RKRRIYDITNVLEGTGLIEKKLKNRIRWRG 88
                     689*******************************...**..9***************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.3E-272089IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.7E-332388IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.3E-172386IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023198.0E-242588IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146601.86E-3998204No hitNo description
SuperFamilySSF1440747.06E-3099204No hitNo description
PfamPF164214.0E-27103202IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 342 aa     Download sequence    Send to blast
MQCTHICISA GSPGNPSTPA SSRYDNSLGL LTRKFINLLK QAQDGTLDLN DAAKILDVRK  60
RRIYDITNVL EGTGLIEKKL KNRIRWRGSD DSGTIFDSDI SCLKTVVENL YIQEQALDRS  120
ISEIREKMEE LTEDESNHRW LFVTEDDIKG LPCFQNEALI AIKGPHGTTV EVPDPDEAGD  180
YLQRRYRILL RSTMGPIDLY LVSQCKKMEE LGETAKPPRH ASVAEPPSIA TEAGQSSKQN  240
MSQNVRQDIQ RTPELNASHA FGRMKKITPS DVDTDADYWL LTDDDISITD MWRTASEMQW  300
DPIDTNNFLA EEISDTPCAL NQPSAADRVR WFPWESASFP RE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A5e-231688273PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
15880RKRRIYDITNVLEGTGLIEKKLK
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK0675810.0AK067581.1 Oryza sativa Japonica Group cDNA clone:J013113N12, full insert sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015637107.10.0transcription factor E2FA isoform X2
SwissprotQ9FNY03e-96E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A0E0KQF50.0A0A0E0KQF5_ORYPU; Uncharacterized protein
STRINGOPUNC04G10160.10.0(Oryza punctata)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-100E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]