PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID ORGLA06G0087600.1
Organism
Oryza glaberrima
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza
Family E2F/DP
Protein Properties Length: 425aa    MW: 46807.4 Da    PI: 8.4244
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
ORGLA06G0087600.1genomeAGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP72.25.8e-2357122171
            E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                        rk+ksL+ll+++f++l+ +++ + v l+++a++L    v  +rRRiYDi+NVLe+++++ +++kn+++w+g
  ORGLA06G0087600.1  57 RKQKSLGLLCTNFVALYDREDVESVGLDDAARRL---GV--ERRRIYDIVNVLESIGMLVRRAKNRYTWIG 122
                        79****************9999************...**..****************************98 PP
2E2F_TDP80.91.1e-25203283171
            E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                        rkeksL+lltq+f+kl+ + e ++++l+e+ak+L+ e     ++++k+RR+YDi+NVL++lnliek     ++k+++rw g
  ORGLA06G0087600.1 203 RKEKSLGLLTQNFVKLFLTMEIETISLDEAAKRLLGEghaanNMRTKVRRLYDIANVLSSLNLIEKtqqadSRKPAFRWLG 283
                        79****************************************************************9999999******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.5E-2553123IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.26E-1656121IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.9E-2857122IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.1E-2058122IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.106.6E-24200284IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.9E-33203283IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023194.7E-21204283IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467855.85E-13205283IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 425 aa     Download sequence    Send to blast
MAAAADAPPP PPEVAPPAPA PAPAPAPYQP PRLAVADGAG GGGGGGGKPC RHHAYSRKQK  60
SLGLLCTNFV ALYDREDVES VGLDDAARRL GVERRRIYDI VNVLESIGML VRRAKNRYTW  120
IGFGGVPAAL AELKEMSLRA VSSVASPSLD ETSAANVSDD EDDDKLDDAE GDAESEKLSL  180
SQSIDNPSDK PDAPPCKLRS EHRKEKSLGL LTQNFVKLFL TMEIETISLD EAAKRLLGEG  240
HAANNMRTKV RRLYDIANVL SSLNLIEKTQ QADSRKPAFR WLGQAKRNEG VTVALPPTKT  300
LPNKRAFGTD LTNIDNKRGK LDSTMENRGK PTQDGGNLFN NLQRQLGQEN RSDFVYGPFH  360
PAGARKQEHG NRTVQEKERK SIQDWENLAS SFRPQYQNPG LNDLFGHYME AWRSWYSDLR  420
RDRAS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A7e-38562753228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapORGLA06G0087600.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK1200320.0AK120032.1 Oryza sativa Japonica Group cDNA clone:002-186-D11, full insert sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015643420.10.0E2F transcription factor-like E2FE
SwissprotQ8LSZ41e-101E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLI1Q1630.0I1Q163_ORYGL; Uncharacterized protein
STRINGORGLA06G0087600.10.0(Oryza glaberrima)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP31853884
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-104DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]