PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_009616443.1

Organism

Nicotiana tomentosiformis

Taxonomic ID

4098

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

WRKY

Protein Properties

Length: 537aa MW: 59463.3 Da PI: 6.2104

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009616443.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	95.3	4.4e-30	247	306	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt a +Cpv+k+v+r+ ed +++++tYeg+Hnh+ XP_009616443.1 247 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVApSCPVRKQVQRCIEDMSILITTYEGTHNHP 306 58*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	7.0E-31	232	306	IPR003657	WRKY domain
SuperFamily	SSF118290	4.84E-27	239	307	IPR003657	WRKY domain
PROSITE profile	PS50811	27.278	242	308	IPR003657	WRKY domain
SMART	SM00774	3.3E-36	247	307	IPR003657	WRKY domain
Pfam	PF03106	1.2E-26	248	306	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0006952	Biological Process	defense response
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 537 aa Download sequence Send to blast
MEVAFRKSIN GGLVKEEKRN KLADQSSSDE EGFVEDSNVL KVGKEREVHE DDNSKYPQQE 60 DIDSDKEDDQ LQSVKADMKE VMKENQRLKM HLDRIMKDYR NLQLQFHDIV QRNAEKSNSI 120 IDTDRHNECN EAEFVSLSLG RSSSDTKKEE YLSKILSKDK AEEENKGGLT LGLDCKFDLC 180 VKTTPTEFST ANLSEENRSE EVKDENGETL PPHKILKTMR NGEDDTQPNP SKRAKVSVRV 240 RCDVPTMNDG CQWRKYGQKI AKGNPCPRAY YRCTVAPSCP VRKQVQRCIE DMSILITTYE 300 GTHNHPLSLS ATSMAFTTSA AASMLLSGSS SSSESGPNPP ATDATNINGL NFYLSDSSKP 360 KPFYLQNSSI SSSSSPPTIT LDLTSSSFTS LFPHHNRMSS NYLPRYNSST NILNFSSLES 420 NPLLPMSWSN GAYNKNQEIS SLNFARRPQD ILFQSYLQNN ISAKPTQSLL PQDTIAAATK 480 AITSDPNFQS ALAVALASII GSGSGNHAGG IEEKSGLNLK VTEPFPVLCS FPSTSKK

Sequence ? help Back to Top

Protein Sequence Length: 537 aa Download sequence Send to blast

MEVAFRKSIN GGLVKEEKRN KLADQSSSDE EGFVEDSNVL KVGKEREVHE DDNSKYPQQE  60
DIDSDKEDDQ LQSVKADMKE VMKENQRLKM HLDRIMKDYR NLQLQFHDIV QRNAEKSNSI  120
IDTDRHNECN EAEFVSLSLG RSSSDTKKEE YLSKILSKDK AEEENKGGLT LGLDCKFDLC  180
VKTTPTEFST ANLSEENRSE EVKDENGETL PPHKILKTMR NGEDDTQPNP SKRAKVSVRV  240
RCDVPTMNDG CQWRKYGQKI AKGNPCPRAY YRCTVAPSCP VRKQVQRCIE DMSILITTYE  300
GTHNHPLSLS ATSMAFTTSA AASMLLSGSS SSSESGPNPP ATDATNINGL NFYLSDSSKP  360
KPFYLQNSSI SSSSSPPTIT LDLTSSSFTS LFPHHNRMSS NYLPRYNSST NILNFSSLES  420
NPLLPMSWSN GAYNKNQEIS SLNFARRPQD ILFQSYLQNN ISAKPTQSLL PQDTIAAATK  480
AITSDPNFQS ALAVALASII GSGSGNHAGG IEEKSGLNLK VTEPFPVLCS FPSTSKK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	2e-19	238	307	8	76	Probable WRKY transcription factor 4
2lex_A	2e-19	238	307	8	76	Probable WRKY transcription factor 4
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009616443.1	0.0	PREDICTED: probable WRKY transcription factor 61
Swissprot	A0A3Q7GFB5	0.0	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A1S4B0U8	0.0	A0A1S4B0U8_TOBAC; probable WRKY transcription factor 61
STRING	XP_009616443.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1945	24	64

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	9e-63	WRKY DNA-binding protein 72

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]