PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_009613616.1

Organism

Nicotiana tomentosiformis

Taxonomic ID

4098

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

CAMTA

Protein Properties

Length: 1106aa MW: 124086 Da PI: 6.0556

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009613616.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	182.4	5.2e-57	20	136	2	118
CG-1 2 lkekkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenptfqr 96 l+ ++rwl++ ei++iL+n++k++++ e+++rp+sgsl+L++rk++ryfrkDG+sw+kkkdgktv+E+he+LK g+++vl+cyYah+een++fqr XP_009613616.1 20 LEAQHRWLRPAEICEILKNYQKFRIAPEPPNRPPSGSLFLFDRKVLRYFRKDGHSWRKKKDGKTVKEAHERLKAGSIDVLHCYYAHGEENENFQR 114 5679***************************************************************************************** PP CG-1 97 rcywlLeeelekivlvhylevk 118 r+yw+Leee+++ivlvhy+evk XP_009613616.1 115 RSYWMLEEEMSHIVLVHYREVK 136 *****************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	83.558	15	141	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	1.9E-79	18	136	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	3.8E-50	21	134	IPR005559	CG-1 DNA-binding domain
SuperFamily	SSF81296	6.72E-15	518	604	IPR014756	Immunoglobulin E-set
Pfam	PF01833	1.8E-4	518	596	IPR002909	IPT domain
PROSITE profile	PS50297	19.465	704	825	IPR020683	Ankyrin repeat-containing domain
CDD	cd00204	1.96E-14	704	813	No hit	No description
Gene3D	G3DSA:1.25.40.20	5.2E-19	705	817	IPR020683	Ankyrin repeat-containing domain
SuperFamily	SSF48403	1.41E-18	709	815	IPR020683	Ankyrin repeat-containing domain
Pfam	PF12796	1.1E-8	726	817	IPR020683	Ankyrin repeat-containing domain
PROSITE profile	PS50088	10.152	754	786	IPR002110	Ankyrin repeat
SMART	SM00248	0.0016	754	783	IPR002110	Ankyrin repeat
SMART	SM00248	22	793	822	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	3.72E-7	922	979	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	50	928	950	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	7.346	930	958	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.18	931	949	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	0.0042	951	973	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.285	952	976	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	5.0E-4	954	973	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 1106 aa Download sequence Send to blast
MADSRRYGLN AQLDIDQILL EAQHRWLRPA EICEILKNYQ KFRIAPEPPN RPPSGSLFLF 60 DRKVLRYFRK DGHSWRKKKD GKTVKEAHER LKAGSIDVLH CYYAHGEENE NFQRRSYWML 120 EEEMSHIVLV HYREVKGNRT NFSRTREPQE AAPRFQETDE DVHSSEVDSS ASTKFYPNDY 180 QVNSQVTDTT SLSSVQASEY EDAESAYNQH PTSGFHSFLD AQPSMTQKAG EGLAVPYHPI 240 PFSNDHQVQF AGSSDMDFFS IAPGNKSGNT ANTYIPSRNL DFPSWETTSV NNPAAYQSYH 300 FQPSSQSGAN NMTHEQGNTK TGQVFLNDFK RQERQNRIDG LGDWQTSEGD AAFISKWSMD 360 QKLHPDLASD HTIRSSAAFN VELHNSLEAS HILPSHQDKH PMQNELPSQL SDPNVGGSLN 420 ADLDHNLSIG VRTDHSSLKQ PLLDGVLREG LKKLDSFDRW MSKELEDVSE PHMQSNSSSY 480 WDNVGDDDGV DNSTIASQVQ LDTYMLSPSL SQDQFFSIID FSPSWAFAGS EIKVLITGKF 540 LKSQPEVEKC SWACMFGELE VPAEVIADGV LRCHTPIQKA GRVPFYITCC NRLACSEVRE 600 FEFRVTEGQD ADVANANSCS SSESLLHMRF GKLLSLESTV SLSSPPRSED DVSHVCSKIN 660 SLLKEDDNEW EEMLNLTYEN NFMAEKVKDQ LLQKLLKEKL RVWLLQKVAE GGKGPNVLDE 720 GGQGVLHFAA ALGYDWAIPP TIAAGVSVNF RDVNGWTALH WAASYGRERT VGFLISLGAA 780 PGALTDPTPK HPSGRTPADL ASSNGHKGIA GYLAESSLSF HLSSLELKEM KQGENVQPFG 840 EAVQTVSERS ATPAWDGDWP HGVSLKDSLA AVRNATQAAA RIHQVFRVQS FQRKQLKEHG 900 GSEFGLSDEH ALSLLALKTN KAGQHDEPVH TAAVRIQNKF RSWKGRRDYL LIRQRIIKIQ 960 AHVRGHQVRN KYKNIIWSVG ILEKVILRWR RKGSGLRGFK PEATLTEGSN TQDRPVQEDD 1020 YDFLKEGRKQ TEQRLQKALA RVKSMVQYPE ARDQYRRLLN VVSDMKDTTT TSDGAPSNSV 1080 EAADFGDDLI DLDDLLDDDT FMSTAP

Sequence ? help Back to Top

Protein Sequence Length: 1106 aa Download sequence Send to blast

MADSRRYGLN AQLDIDQILL EAQHRWLRPA EICEILKNYQ KFRIAPEPPN RPPSGSLFLF  60
DRKVLRYFRK DGHSWRKKKD GKTVKEAHER LKAGSIDVLH CYYAHGEENE NFQRRSYWML  120
EEEMSHIVLV HYREVKGNRT NFSRTREPQE AAPRFQETDE DVHSSEVDSS ASTKFYPNDY  180
QVNSQVTDTT SLSSVQASEY EDAESAYNQH PTSGFHSFLD AQPSMTQKAG EGLAVPYHPI  240
PFSNDHQVQF AGSSDMDFFS IAPGNKSGNT ANTYIPSRNL DFPSWETTSV NNPAAYQSYH  300
FQPSSQSGAN NMTHEQGNTK TGQVFLNDFK RQERQNRIDG LGDWQTSEGD AAFISKWSMD  360
QKLHPDLASD HTIRSSAAFN VELHNSLEAS HILPSHQDKH PMQNELPSQL SDPNVGGSLN  420
ADLDHNLSIG VRTDHSSLKQ PLLDGVLREG LKKLDSFDRW MSKELEDVSE PHMQSNSSSY  480
WDNVGDDDGV DNSTIASQVQ LDTYMLSPSL SQDQFFSIID FSPSWAFAGS EIKVLITGKF  540
LKSQPEVEKC SWACMFGELE VPAEVIADGV LRCHTPIQKA GRVPFYITCC NRLACSEVRE  600
FEFRVTEGQD ADVANANSCS SSESLLHMRF GKLLSLESTV SLSSPPRSED DVSHVCSKIN  660
SLLKEDDNEW EEMLNLTYEN NFMAEKVKDQ LLQKLLKEKL RVWLLQKVAE GGKGPNVLDE  720
GGQGVLHFAA ALGYDWAIPP TIAAGVSVNF RDVNGWTALH WAASYGRERT VGFLISLGAA  780
PGALTDPTPK HPSGRTPADL ASSNGHKGIA GYLAESSLSF HLSSLELKEM KQGENVQPFG  840
EAVQTVSERS ATPAWDGDWP HGVSLKDSLA AVRNATQAAA RIHQVFRVQS FQRKQLKEHG  900
GSEFGLSDEH ALSLLALKTN KAGQHDEPVH TAAVRIQNKF RSWKGRRDYL LIRQRIIKIQ  960
AHVRGHQVRN KYKNIIWSVG ILEKVILRWR RKGSGLRGFK PEATLTEGSN TQDRPVQEDD  1020
YDFLKEGRKQ TEQRLQKALA RVKSMVQYPE ARDQYRRLLN VVSDMKDTTT TSDGAPSNSV  1080
EAADFGDDLI DLDDLLDDDT FMSTAP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4hb5_A	5e-12	705	813	20	122	Engineered Protein
4hb5_B	5e-12	705	813	20	122	Engineered Protein
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	GU170838	0.0	GU170838.1 Solanum lycopersicum cultivar Rutgers calmodulin-binding protein mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009613616.1	0.0	PREDICTED: calmodulin-binding transcription activator 3 isoform X2
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A1S3YKL0	0.0	A0A1S3YKL0_TOBAC; Calmodulin-binding transcription activator 4
STRING	XP_009613615.1	0.0	(Nicotiana tomentosiformis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G64220.2	0.0	Calmodulin-binding transcription activator protein with CG-1 and Ankyrin domains

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]