PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009595315.1
Organism
Nicotiana tomentosiformis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family TALE
Protein Properties Length: 321aa    MW: 36147.2 Da    PI: 4.707
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009595315.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox26.31.2e-082673002255
                     SSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
        Homeobox  22 nrypsaeereeLAkklgLterqVkvWFqNrRake 55 
                      +yp++ ++  LA+++gL+ +q+ +WF N+R ++
  XP_009595315.1 267 WPYPTEGQKICLAESTGLDPKQINNWFINQRKRH 300
                     58*****************************885 PP
2ELK383.5e-13221242122
             ELK   1 ELKhqLlrKYsgyLgsLkqEFs 22 
                     E+K+ L+rKYsgy++sLkqEFs
  XP_009595315.1 221 EIKDKLRRKYSGYISSLKQEFS 242
                     89*******************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM012552.3E-1278123IPR005540KNOX1
PfamPF037904.8E-1680117IPR005540KNOX1
SMARTSM012563.6E-21128179IPR005541KNOX2
PfamPF037911.9E-22133178IPR005541KNOX2
PfamPF037893.7E-10221242IPR005539ELK domain
PROSITE profilePS5121310.964221241IPR005539ELK domain
SMARTSM011883.6E-7221242IPR005539ELK domain
PROSITE profilePS5007111.629240303IPR001356Homeobox domain
SMARTSM003893.0E-10242307IPR001356Homeobox domain
SuperFamilySSF466893.94E-19243314IPR009057Homeodomain-like
CDDcd000864.77E-12243304No hitNo description
Gene3DG3DSA:1.10.10.601.5E-27245305IPR009057Homeodomain-like
PfamPF059202.8E-16260299IPR008422Homeobox KN domain
PROSITE patternPS000270278301IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 321 aa     Download sequence    Send to blast
MEEMYEFGYS SSDVYSVEDN LQPPYFGSPP AFCDGLAPMG FGSGNMSWAC PETSAANLVV  60
DKIGTSSSNL QLEDHHETDI RAKISSHPLY PKLLRTYIDC HKVGAPSDEI VDMLDNINIV  120
HENDLFRRSN RLSDDSELDA FMGTYCDVLA KFKSDLERPF NEATTFLNDI ETQLTNLCAA  180
PATTISNISD EGAAGLEEEA AAADTSGGGG NTNDMCRSDN EIKDKLRRKY SGYISSLKQE  240
FSKNKKGKLP REARQILLNW WTTHYKWPYP TEGQKICLAE STGLDPKQIN NWFINQRKRH  300
WKPSENMQYA VMESIYGHFS E
Functional Description ? help Back to Top
Source Description
UniProtMay play a role in meristem function, and may be involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0257130.0AB025713.1 Nicotiana tabacum mRNA for homeobox 9, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009595315.10.0PREDICTED: homeobox protein knotted-1-like 2
SwissprotP466406e-86KNAT2_ARATH; Homeobox protein knotted-1-like 2
TrEMBLQ9SXV20.0Q9SXV2_TOBAC; Homeobox 9
STRINGXP_009595315.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA7532480
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G70510.13e-84KNOTTED-like from Arabidopsis thaliana 2
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Zhang XL,Yang ZP,Zhang J,Zhang LG
    Ectopic expression of BraYAB1-702, a member of YABBY gene family in Chinese cabbage, causes leaf curling, inhibition of development of shoot apical meristem and flowering stage delaying in Arabidopsis thaliana.
    Int J Mol Sci, 2013. 14(7): p. 14872-91
    [PMID:23863694]
  3. Kuijt SJ, et al.
    Interaction between the GROWTH-REGULATING FACTOR and KNOTTED1-LIKE HOMEOBOX families of transcription factors.
    Plant Physiol., 2014. 164(4): p. 1952-66
    [PMID:24532604]
  4. Scofield S,Dewitte W,Murray JA
    STM sustains stem cell function in the Arabidopsis shoot apical meristem and controls KNOX gene expression independently of the transcriptional repressor AS1.
    Plant Signal Behav, 2018.
    [PMID:24776954]
  5. Lee JE,Lampugnani ER,Bacic A,Golz JF
    SEUSS and SEUSS-LIKE 2 coordinate auxin distribution and KNOXI activity during embryogenesis.
    Plant J., 2014. 80(1): p. 122-35
    [PMID:25060324]
  6. Machida C,Nakagawa A,Kojima S,Takahashi H,Machida Y
    The complex of ASYMMETRIC LEAVES (AS) proteins plays a central role in antagonistic interactions of genes for leaf polarity specification in Arabidopsis.
    Wiley Interdiscip Rev Dev Biol, 2015 Nov-Dec. 4(6): p. 655-71
    [PMID:26108442]
  7. Li Z, et al.
    Transcription factors AS1 and AS2 interact with LHP1 to repress KNOX genes in Arabidopsis.
    J Integr Plant Biol, 2016. 58(12): p. 959-970
    [PMID:27273574]
  8. Lozano-Sotomayor P, et al.
    Altered expression of the bZIP transcription factor DRINK ME affects growth and reproductive development in Arabidopsis thaliana.
    Plant J., 2016. 88(3): p. 437-451
    [PMID:27402171]